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B3H084 (ARGB_ACTP7) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 26. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Acetylglutamate kinase

EC=2.7.2.8
Alternative name(s):
N-acetyl-L-glutamate 5-phosphotransferase
NAG kinase
Short name=AGK
Gene names
Name:argB
Ordered Locus Names:APP7_0244
OrganismActinobacillus pleuropneumoniae serotype 7 (strain AP76) [Complete proteome] [HAMAP]
Taxonomic identifier537457 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeActinobacillus

Protein attributes

Sequence length284 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamate 5-phosphate. HAMAP MF_00082_B

Pathway

Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 2/4. HAMAP MF_00082_B

Subcellular location

Cytoplasm By similarity HAMAP MF_00082_B.

Sequence similarities

Belongs to the acetylglutamate kinase family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 284284Acetylglutamate kinase HAMAP MF_00082_B
PRO_1000092844

Regions

Region66 – 672Substrate binding By similarity

Sites

Binding site881Substrate By similarity
Binding site1791Substrate By similarity
Site311Transition state stabilizer By similarity
Site2421Transition state stabilizer By similarity

Sequences

Sequence LengthMass (Da)Tools
B3H084 [UniParc].

Last modified July 22, 2008. Version 1.
Checksum: 7A1756715E71C3B4

FASTA28430,275
        10         20         30         40         50         60 
MLQNEVENFA NLLEQATVYL APYQEKIIVV KYGGNAMINE DLKKLVMQDI LLLNQLGVKV 

        70         80         90        100        110        120 
VLVHGGGPEI SQGVKLLGKE PQFINGLRVT DQDTINVVLQ MLAGKVNKSL VALLKGKGVG 

       130        140        150        160        170        180 
LCGIDANMLQ CEKLQAEVDY GFVGEIVKVN TQLLELALSA NLIPVISTVG VDDQGVAYNI 

       190        200        210        220        230        240 
NADTVASEIA MALGAAKLVS MTDIAGLLRD RFDESTLIPE VEVSEVQGLI DQGIIAGGMI 

       250        260        270        280 
PKIACCTDFI NAGGIEANII DGRVPHAILV SLFGGKNGTL FYKK 

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References

[1]"Genome and proteome analysis of A. pleuropneumoniae serotype 7."
Linke B., Buettner F., Martinez-Arias R., Goesmann A., Baltes N., Tegetmeyer H., Singh M., Gerlach G.F.
Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: AP76.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001091 Genomic DNA. Translation: ACE60896.1.
RefSeqYP_001968038.1. NC_010939.1.

3D structure databases

ProteinModelPortalB3H084.
ModBaseSearch...

Protein-protein interaction databases

STRINGB3H084.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6397148.
GenomeReviewsGene locus APP7_0244 in contig CP001091_GR.
KEGGapa:APP7_0244.
PATRIC20754055. VBIActPle116979_0248.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG497643.
OMAGGNAMID.
ProtClustDBPRK00942.

Family and domain databases

HAMAPMF_00082_B. ArgB_B.
[Tree]
InterProIPR004662. AcgluKinase.
IPR001048. Asp/Glu/Uridylate_kinase.
IPR001057. Glu/AcGlu_kinase.
[Graphical view]
Gene3DG3DSA:3.40.1160.10. Aa_kinase. 1 hit.
KOK00930.
PfamPF00696. AA_kinase. 1 hit.
[Graphical view]
PIRSFPIRSF000728. NAGK. 1 hit.
PRINTSPR00474. GLU5KINASE.
SUPFAMSSF53633. Aa_kinase. 1 hit.
TIGRFAMsTIGR00761. ArgB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameARGB_ACTP7
AccessionPrimary (citable) accession number: B3H084
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: July 22, 2008
Last modified: January 25, 2012
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families