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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Actinobacillus pleuropneumoniae serotype 7 (strain AP76)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei144GTPUniRule annotation1
Binding sitei148GTPUniRule annotation1
Binding sitei192GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi21 – 25GTPUniRule annotation5
Nucleotide bindingi113 – 115GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, SeptationUniRule annotation
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotationImported
Ordered Locus Names:APP7_0023Imported
OrganismiActinobacillus pleuropneumoniae serotype 7 (strain AP76)Imported
Taxonomic identifieri537457 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeActinobacillus
Proteomesi
  • UP000001226 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini13 – 210TubulinInterPro annotationAdd BLAST198
Domaini212 – 330Tubulin_CInterPro annotationAdd BLAST119

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000049094
KOiK03531
OMAiMRAVKGI
OrthoDBiPOG091H02KK

Family and domain databases

CDDicd02201 FtsZ_type1, 1 hit
Gene3Di3.40.50.1440, 1 hit
HAMAPiMF_00909 FtsZ, 1 hit
InterProiView protein in InterPro
IPR000158 Cell_div_FtsZ
IPR020805 Cell_div_FtsZ_CS
IPR024757 FtsZ_C
IPR008280 Tub_FtsZ_C
IPR018316 Tubulin/FtsZ_2-layer-sand-dom
IPR036525 Tubulin/FtsZ_GTPase_sf
IPR003008 Tubulin_FtsZ_GTPase
PfamiView protein in Pfam
PF12327 FtsZ_C, 1 hit
PF00091 Tubulin, 1 hit
PRINTSiPR00423 CELLDVISFTSZ
SMARTiView protein in SMART
SM00864 Tubulin, 1 hit
SM00865 Tubulin_C, 1 hit
SUPFAMiSSF52490 SSF52490, 1 hit
SSF55307 SSF55307, 1 hit
TIGRFAMsiTIGR00065 ftsZ, 1 hit
PROSITEiView protein in PROSITE
PS01134 FTSZ_1, 1 hit
PS01135 FTSZ_2, 1 hit

Sequencei

Sequence statusi: Complete.

B3GZL3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFEPIYETTQ DAVIKVVGVG GGGGNALNHM VDGNLNNEGV GGVEFFSVNT
60 70 80 90 100
DAQVLRTSSV RQTIQIGANI TKGLGAGANP NVGRQAAEED REALSNMLAG
110 120 130 140 150
ADMVFISAGM GGGTGTGAAP VIADIAKSQG SLTVAIVTKP FRFEGNKRMN
160 170 180 190 200
YAEQGIQELS KHVDSLIIIP NDKLLKVLPK NTKMMDAFKA ANDILRNAVL
210 220 230 240 250
GITDMITSPG LINVDFADVK TVMSEMGRAM MGTGIAEGED RAEHAAHDAV
260 270 280 290 300
ASPLLEDVDL SGAKGILVSI SSGLDIELNE VDVIMDYIHS FAAPDATIVF
310 320 330 340 350
GTSVYPEMEG KLRVTLVATG IGQAEELTLP RATVVPQQMQ QPMQQQSYQQ
360 370 380 390 400
QAQQPQQPAF AQQGYAQPAQ FAQPQQAAPK PQQVDSSQVW SPNSIPGFMR

NGQ
Length:403
Mass (Da):42,667
Last modified:July 22, 2008 - v1
Checksum:iB86DC311A9149DC1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001091 Genomic DNA Translation: ACE60675.1
RefSeqiWP_005603042.1, NC_010939.1

Genome annotation databases

EnsemblBacteriaiACE60675; ACE60675; APP7_0023
KEGGiapa:APP7_0023

Similar proteinsi

Entry informationi

Entry nameiB3GZL3_ACTP7
AccessioniPrimary (citable) accession number: B3GZL3
Entry historyiIntegrated into UniProtKB/TrEMBL: July 22, 2008
Last sequence update: July 22, 2008
Last modified: March 28, 2018
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
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Main funding by: National Institutes of Health