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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Actinobacillus pleuropneumoniae serotype 7 (strain AP76)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei144GTPUniRule annotation1
Binding sitei148GTPUniRule annotation1
Binding sitei192GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi21 – 25GTPUniRule annotation5
Nucleotide bindingi113 – 115GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Cell cycle, Cell division, SeptationUniRule annotation

Keywords - Ligandi

GTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotationImported
Ordered Locus Names:APP7_0023Imported
OrganismiActinobacillus pleuropneumoniae serotype 7 (strain AP76)Imported
Taxonomic identifieri537457 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeActinobacillus
Proteomesi
  • UP000001226 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini13 – 210TubulinInterPro annotationAdd BLAST198
Domaini212 – 330Tubulin_CInterPro annotationAdd BLAST119

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000049094.
KOiK03531.
OMAiNNAREEL.
OrthoDBiPOG091H02KK.

Family and domain databases

CDDicd02201. FtsZ_type1. 1 hit.
Gene3Di3.30.1330.20. 1 hit.
3.40.50.1440. 1 hit.
HAMAPiMF_00909. FtsZ. 1 hit.
InterProiIPR000158. Cell_div_FtsZ.
IPR020805. Cell_div_FtsZ_CS.
IPR024757. FtsZ_C.
IPR008280. Tub_FtsZ_C.
IPR018316. Tubulin/FtsZ_2-layer-sand-dom.
IPR003008. Tubulin_FtsZ_GTPase.
[Graphical view]
PfamiPF12327. FtsZ_C. 1 hit.
PF00091. Tubulin. 1 hit.
[Graphical view]
PRINTSiPR00423. CELLDVISFTSZ.
SMARTiSM00864. Tubulin. 1 hit.
SM00865. Tubulin_C. 1 hit.
[Graphical view]
SUPFAMiSSF52490. SSF52490. 1 hit.
SSF55307. SSF55307. 1 hit.
TIGRFAMsiTIGR00065. ftsZ. 1 hit.
PROSITEiPS01134. FTSZ_1. 1 hit.
PS01135. FTSZ_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B3GZL3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFEPIYETTQ DAVIKVVGVG GGGGNALNHM VDGNLNNEGV GGVEFFSVNT
60 70 80 90 100
DAQVLRTSSV RQTIQIGANI TKGLGAGANP NVGRQAAEED REALSNMLAG
110 120 130 140 150
ADMVFISAGM GGGTGTGAAP VIADIAKSQG SLTVAIVTKP FRFEGNKRMN
160 170 180 190 200
YAEQGIQELS KHVDSLIIIP NDKLLKVLPK NTKMMDAFKA ANDILRNAVL
210 220 230 240 250
GITDMITSPG LINVDFADVK TVMSEMGRAM MGTGIAEGED RAEHAAHDAV
260 270 280 290 300
ASPLLEDVDL SGAKGILVSI SSGLDIELNE VDVIMDYIHS FAAPDATIVF
310 320 330 340 350
GTSVYPEMEG KLRVTLVATG IGQAEELTLP RATVVPQQMQ QPMQQQSYQQ
360 370 380 390 400
QAQQPQQPAF AQQGYAQPAQ FAQPQQAAPK PQQVDSSQVW SPNSIPGFMR

NGQ
Length:403
Mass (Da):42,667
Last modified:July 22, 2008 - v1
Checksum:iB86DC311A9149DC1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001091 Genomic DNA. Translation: ACE60675.1.
RefSeqiWP_005603042.1. NC_010939.1.

Genome annotation databases

EnsemblBacteriaiACE60675; ACE60675; APP7_0023.
KEGGiapa:APP7_0023.
PATRICi20753591. VBIActPle116979_0023.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001091 Genomic DNA. Translation: ACE60675.1.
RefSeqiWP_005603042.1. NC_010939.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACE60675; ACE60675; APP7_0023.
KEGGiapa:APP7_0023.
PATRICi20753591. VBIActPle116979_0023.

Phylogenomic databases

HOGENOMiHOG000049094.
KOiK03531.
OMAiNNAREEL.
OrthoDBiPOG091H02KK.

Family and domain databases

CDDicd02201. FtsZ_type1. 1 hit.
Gene3Di3.30.1330.20. 1 hit.
3.40.50.1440. 1 hit.
HAMAPiMF_00909. FtsZ. 1 hit.
InterProiIPR000158. Cell_div_FtsZ.
IPR020805. Cell_div_FtsZ_CS.
IPR024757. FtsZ_C.
IPR008280. Tub_FtsZ_C.
IPR018316. Tubulin/FtsZ_2-layer-sand-dom.
IPR003008. Tubulin_FtsZ_GTPase.
[Graphical view]
PfamiPF12327. FtsZ_C. 1 hit.
PF00091. Tubulin. 1 hit.
[Graphical view]
PRINTSiPR00423. CELLDVISFTSZ.
SMARTiSM00864. Tubulin. 1 hit.
SM00865. Tubulin_C. 1 hit.
[Graphical view]
SUPFAMiSSF52490. SSF52490. 1 hit.
SSF55307. SSF55307. 1 hit.
TIGRFAMsiTIGR00065. ftsZ. 1 hit.
PROSITEiPS01134. FTSZ_1. 1 hit.
PS01135. FTSZ_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiB3GZL3_ACTP7
AccessioniPrimary (citable) accession number: B3GZL3
Entry historyi
Integrated into UniProtKB/TrEMBL: July 22, 2008
Last sequence update: July 22, 2008
Last modified: November 30, 2016
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.