Skip Header

Contribute Send feedback
Read comments (?) or add your own

B3GY24 (G6PI_ACTP7) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 21. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase
Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:APP7_1195
OrganismActinobacillus pleuropneumoniae serotype 7 (strain AP76) [Complete proteome] [HAMAP]
Taxonomic identifier537457 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Actinobacillus

Protein attributes

Sequence length546 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP MF_00473

Pathway

Carbohydrate biosynthesis; gluconeogenesis. HAMAP MF_00473

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP MF_00473

Subcellular location

Cytoplasm By similarity HAMAP MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-KW

glycolysis

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 546546Glucose-6-phosphate isomerase HAMAP MF_00473
PRO_1000125686

Sites

Active site3841 By similarity
Active site5121 By similarity

Sequences

Sequence LengthMass (Da)Tools
B3GY24 [UniParc].

Last modified July 22, 2008. Version 1.
Checksum: 6787F092BEE82DEE

FASTA54660,415
        10         20         30         40         50         60 
MQNINPTQTA AWSALEQHKA DNLNIPQLFA EDANRFDKYH LNFEQQILVD FSKNAINQKT 

        70         80         90        100        110        120 
LELLRQLANE CGLASATEAM FSGQKINRTE NRAVLHTALR NRSNTPVLVD GKDVMPEVNA 

       130        140        150        160        170        180 
VLAKMKDFCE RIISGSWKGY TGKAITDVIN IGIGGSDLGP YMVTEALRPY KNHLNMHFVS 

       190        200        210        220        230        240 
NVDGTHIAEV LKKVNPETTL VLVASKTFTT QETMTNALTA REWLLAAVKD ESAVAKHFAA 

       250        260        270        280        290        300 
LSTNAKEVAK FGIDTANMFE FWDWVGGRYS LWSAIGLSIA LSLGFENFEA LLSGAHAMDN 

       310        320        330        340        350        360 
HFRTAPIEKN IPTTLALIGI WNSNFLGAET EALLPYDQYL HRFAAYFQQG NMESNGKFVG 

       370        380        390        400        410        420 
RDGSPVTHQT GPIVWGEPGT NGQHAFYQLI HQGTKLIPCD FIAPAQTHNP VGDHHAKLLS 

       430        440        450        460        470        480 
NFFAQTEALA FGKSKETVEA EFVAAGKNLA DVAEIVPFKV FTGNKPTNSI LVQKITPFTL 

       490        500        510        520        530        540 
GALIAMYEHK IFVQGVIFNI YSFDQWGVEL GKQLANRILP ELQNAEKISS HDSSTNGLIN 


QFKAWR

« Hide

References

[1]"Genome and proteome analysis of A. pleuropneumoniae serotype 7."
Linke B., Buettner F., Martinez-Arias R., Goesmann A., Baltes N., Tegetmeyer H., Singh M., Gerlach G.F.
Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: AP76.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001091 Genomic DNA. Translation: ACE61847.1.
RefSeqYP_001968989.1. NC_010939.1.

3D structure databases

ProteinModelPortalB3GY24.
SMRB3GY24. Positions 17-546.
ModBaseSearch...

Protein-protein interaction databases

STRINGB3GY24.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6397810.
GenomeReviewsGene locus APP7_1195 in contig CP001091_GR.
KEGGapa:APP7_1195.
PATRIC20756037. VBIActPle116979_1220.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG352954.
OMAGPKIVSQ.
ProtClustDBPRK00179.

Family and domain databases

HAMAPMF_00473. G6P_isomerase.
[Tree]
InterProIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
Gene3DG3DSA:1.10.1390.10. G6P_Isomerase_C. 1 hit.
KOK01810.
PANTHERPTHR11469. G6P_Isomerase. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_ACTP7
AccessionPrimary (citable) accession number: B3GY24
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: July 22, 2008
Last modified: January 25, 2012
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents