B3GY07 (GCP_ACTP7) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp

Alternative name(s):
t(6)A37 threonylcarbamoyladenosine biosynthesis protein

Gene names

Name:	gcp
Ordered Locus Names:	APP7_1178

Organism

Actinobacillus pleuropneumoniae serotype 7 (strain AP76) [Complete proteome] [HAMAP]

Taxonomic identifier

537457 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Actinobacillus

Protein attributes

Sequence length	347 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine By similarity. HAMAP MF_01445
Subcellular location	Cytoplasm Potential HAMAP MF_01445.
Sequence similarities	Belongs to the KAE1 / YgjD family.

Ontologies

Keywords
Biological process	tRNA processing
Cellular component	Cytoplasm
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro tRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 347	347	Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp HAMAP MF_01445		PRO_1000145943

Sequences

	Sequence		Length	Mass (Da)
	B3GY07 [UniParc]. Last modified July 22, 2008. Version 1. Checksum: E18B7948F4819501	FASTA	347	37,518
	10 20 30 40 50 60 MRILGIETSC DETGVAIYDE EKGLVANQLY SQIEMHADYG GVVPELASRD HIRKTLPLIQ 70 80 90 100 110 120 EALKEANLTA ADIDGVVYTA GPGLVGALLV GSTIARSLAY AWNVPALGVH HMEGHLMAPM 130 140 150 160 170 180 LEDNPPAFPF VALLISGGHT QLVKVEGVGQ YEILGESIDD AAGEAFDKTG KLLGLDYPAG 190 200 210 220 230 240 VAVSQLAEKG TPNRFVFPRP MTDRPGLDFS FSGLKTFAAN TINANLDENG RLDEQTRCDI 250 260 270 280 290 300 AHAFQQAVVD TIIIKCKRAL QQTGYKRLVM AGGVSANKQL RTDLAEMMKN LKGEVYYPRP 310 320 330 340 QFCTDNGAMI AYTGFLRLKN GETSDLSISV KPRWNMTELP DISTTGG

References

[1]	"Genome and proteome analysis of A. pleuropneumoniae serotype 7." Linke B., Buettner F., Martinez-Arias R., Goesmann A., Baltes N., Tegetmeyer H., Singh M., Gerlach G.F. Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AP76.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001091 Genomic DNA. Translation: ACE61830.1.
RefSeq	YP_001968972.1. NC_010939.1.
3D structure databases
ProteinModelPortal	B3GY07.
ModBase	Search...
Protein-protein interaction databases
STRING	B3GY07.
Protein family/group databases
MEROPS	M22.001.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6397768.
GenomeReviews	Gene locus APP7_1178 in contig CP001091_GR.
KEGG	apa:APP7_1178.
PATRIC	20756003. VBIActPle116979_1203.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG304663.
OMA	PAVGVHH.
ProtClustDB	PRK09604.
Family and domain databases
HAMAP	MF_01445. gcp. [Tree]
InterPro	IPR022450. Pept_M22_O-sialoglycopept. IPR000905. Peptidase_M22. IPR017860. Peptidase_M22_CS. IPR017861. Peptidase_M22_subgr. [Graphical view]
KO	K01409.
Pfam	PF00814. Peptidase_M22. 1 hit. [Graphical view]
PRINTS	PR00789. OSIALOPTASE.
TIGRFAMs	TIGR03723. Bact_gcp. 1 hit. TIGR00329. Gcp_kae1. 1 hit.
PROSITE	PS01016. GLYCOPROTEASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GCP_ACTP7

Accession

Primary (citable) accession number: B3GY07

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	July 22, 2008
Last modified:	January 25, 2012
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program