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Protein

Bis(5'-nucleosyl)-tetraphosphatase, symmetrical

Gene

apaH

Organism
Actinobacillus pleuropneumoniae serotype 7 (strain AP76)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.UniRule annotation

Catalytic activityi

P1,P4-bis(5'-adenosyl) tetraphosphate + H2O = 2 ADP.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Bis(5'-nucleosyl)-tetraphosphatase, symmetricalUniRule annotation (EC:3.6.1.41UniRule annotation)
Alternative name(s):
Ap4A hydrolaseUniRule annotation
Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolaseUniRule annotation
Diadenosine tetraphosphataseUniRule annotation
Gene namesi
Name:apaHUniRule annotation
Ordered Locus Names:APP7_0804
OrganismiActinobacillus pleuropneumoniae serotype 7 (strain AP76)
Taxonomic identifieri537457 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeActinobacillus
Proteomesi
  • UP000001226 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000993131 – 270Bis(5'-nucleosyl)-tetraphosphatase, symmetricalAdd BLAST270

Structurei

3D structure databases

ProteinModelPortaliB3GXJ7
SMRiB3GXJ7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Ap4A hydrolase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000251871
KOiK01525
OMAiMPWFDVP
OrthoDBiPOG091H0691

Family and domain databases

CDDicd07422 MPP_ApaH, 1 hit
Gene3Di3.60.21.10, 1 hit
HAMAPiMF_00199 ApaH, 1 hit
InterProiView protein in InterPro
IPR004617 ApaH
IPR004843 Calcineurin-like_PHP_ApaH
IPR029052 Metallo-depent_PP-like
PfamiView protein in Pfam
PF00149 Metallophos, 1 hit
PIRSFiPIRSF000903 B5n-ttraPtase_sm, 1 hit
TIGRFAMsiTIGR00668 apaH, 1 hit

Sequencei

Sequence statusi: Complete.

B3GXJ7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATYIVGDLH GCFDELQLLL KQVNYNPAQD ELWLTGDLVA RGAKSLECLR
60 70 80 90 100
FVKDPKNNAK TILGNHDLHL LATLLGVKKV KPNDQVDAIF AAEDRADLQN
110 120 130 140 150
WLRNQPLLIQ HPKYGFLLTH AGISPEWNLT ETIACAREAE AVLQSGHYAD
160 170 180 190 200
YIAQMYENTP DHWSAEWQGI ERWRYIINVF TRMRFCYADK RLDFACKLPV
210 220 230 240 250
EDAPNELKPW FKLDNPLFHQ QDIIFGHWAS LMGKADKPNI YALDTGCAWG
260 270
NHLTMIRWED KQIFTQERLK
Length:270
Mass (Da):31,224
Last modified:July 22, 2008 - v1
Checksum:i9D0715E800D9020D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001091 Genomic DNA Translation: ACE61456.1
RefSeqiWP_011848461.1, NC_010939.1

Genome annotation databases

EnsemblBacteriaiACE61456; ACE61456; APP7_0804
GeneIDi4849814
KEGGiapa:APP7_0804
PATRICifig|416269.6.peg.795

Similar proteinsi

Entry informationi

Entry nameiAPAH_ACTP7
AccessioniPrimary (citable) accession number: B3GXJ7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: July 22, 2008
Last modified: March 28, 2018
This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
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Main funding by: National Institutes of Health