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B3GXI4 (AROC_ACTP7) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 23. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Chorismate synthase
EC=4.2.3.5
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate phospholyase
Gene names
Name:aroC
Ordered Locus Names:APP7_0791
OrganismActinobacillus pleuropneumoniae serotype 7 (strain AP76) [Complete proteome] [HAMAP]
Taxonomic identifier537457 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Actinobacillus

Protein attributes

Sequence length360 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate. HAMAP MF_00300

Cofactor

Reduced flavin By similarity. HAMAP MF_00300

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7. HAMAP MF_00300

Subunit structure

Homotetramer By similarity. HAMAP MF_00300

Sequence similarities

Belongs to the chorismate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionchorismate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 360360Chorismate synthase HAMAP MF_00300
PRO_1000115322

Sequences

Sequence LengthMass (Da)Tools
B3GXI4 [UniParc].

Last modified July 22, 2008. Version 1.
Checksum: 669FE8A217E9AED6

FASTA36038,951
        10         20         30         40         50         60 
MAGNSIGQLF KVTTFGESHG IALGCIVDGV PPNMALSEAD IQPDLDRRKP GTSRYTTPRR 

        70         80         90        100        110        120 
EDDEVQILSG VFEGKTTGTS IGLIIKNADQ RSKDYGDIAD KFRPGHADYT YQQKYGIRDY 

       130        140        150        160        170        180 
RGGGRSSARE TAMRVAAGAI AKKYLREQFG IEVRGYLSQI GNVKINPETV ADISKIDWQQ 

       190        200        210        220        230        240 
VASNPFFCPD PVAVEGFDEL IRELKKDGDS IGAKLTVVAE NVPVGLGEPV FDRLDADLAH 

       250        260        270        280        290        300 
ALMSINAVKA VEIGDGFDVV EQRGSEHRDE MTPQGFVSNH AGGILGGISS GQPIIAHIAL 

       310        320        330        340        350        360 
KPTSSIMVPG RSVNLNNEQV ELITKGRHDP CVGIRAVPIA EAMTAIILLD HLLRFKAQCR

« Hide

References

[1]"Genome and proteome analysis of A. pleuropneumoniae serotype 7."
Linke B., Buettner F., Martinez-Arias R., Goesmann A., Baltes N., Tegetmeyer H., Singh M., Gerlach G.F.
Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: AP76.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001091 Genomic DNA. Translation: ACE61443.1.
RefSeqYP_001968585.1. NC_010939.1.

3D structure databases

ProteinModelPortalB3GXI4.
ModBaseSearch...

Protein-protein interaction databases

STRINGB3GXI4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6396093.
GenomeReviewsGene locus APP7_0791 in contig CP001091_GR.
KEGGapa:APP7_0791.
PATRIC20755205. VBIActPle116979_0812.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG292336.
OMASRFTTQR.
ProtClustDBPRK05382.

Family and domain databases

HAMAPMF_00300. Chorismate_synth.
[Tree]
InterProIPR000453. Chorismate_synth.
IPR020541. Chorismate_synthase_CS.
[Graphical view]
KOK01736.
PANTHERPTHR21085. Chorismate_synth. 1 hit.
PfamPF01264. Chorismate_synt. 1 hit.
[Graphical view]
PIRSFPIRSF001456. Chorismate_synth. 1 hit.
SUPFAMSSF103263. Chorismate_synth. 1 hit.
TIGRFAMsTIGR00033. AroC. 1 hit.
PROSITEPS00787. CHORISMATE_SYNTHASE_1. 1 hit.
PS00788. CHORISMATE_SYNTHASE_2. 1 hit.
PS00789. CHORISMATE_SYNTHASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROC_ACTP7
AccessionPrimary (citable) accession number: B3GXI4
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: July 22, 2008
Last modified: January 25, 2012
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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