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Protein

Laccase

Gene
N/A
Organism
Agaricus placomyces (Mushroom)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Lignin degradation and detoxification of lignin-derived products.By similarity

Catalytic activityi

4 benzenediol + O2 = 4 benzosemiquinone + 2 H2O.1 Publication

Kineticsi

  1. KM=0.392 mM for hydroquinone1 Publication
  2. KM=0.775 mM for ABTS1 Publication

pH dependencei

Optimum pH is 5.2 with ABTS as substrate. Optimum pH is 6.8 with hydroquinone as substrate.1 Publication

Temperature dependencei

Optimum temperature is 30 degrees Celsius.1 Publication

GO - Molecular functioni

  1. hydroquinone:oxygen oxidoreductase activity Source: UniProtKB-EC

GO - Biological processi

  1. lignin catabolic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Lignin degradation

Names & Taxonomyi

Protein namesi
Recommended name:
Laccase1 Publication (EC:1.10.3.21 Publication)
OrganismiAgaricus placomyces (Mushroom)
Taxonomic identifieri182818 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaBasidiomycotaAgaricomycotinaAgaricomycetesAgaricomycetidaeAgaricalesAgaricaceaeAgaricus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – ›15›15LaccasePRO_0000417451Add
BLAST

Sequencei

Sequence statusi: Fragment.

B3EWI3-1 [UniParc]FASTAAdd to basket

« Hide

        10 
DVIGPQAQVT LANQD
Length:15
Mass (Da):1,569
Last modified:May 15, 2012 - v1
Checksum:iCFF7C40A165E6882
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei15 – 1511 Publication

Cross-referencesi

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

ProtoNetiSearch...

Publicationsi

  1. "A laccase with antiproliferative activity against tumor cells from the mycorrhizal fungus Agaricus placomyces."
    Sun J., Wu Y.Y., Xu L.J., Zhu M.J., Zhang G.Q., Wang H.X.
    Submitted (FEB-2012) to UniProtKB
    Cited for: PROTEIN SEQUENCE, CATALYTIC ACTIVITY, BIOPHYSICOCHEMICAL PROPERTIES.
    Tissue: Fruiting body1 Publication.

Entry informationi

Entry nameiLAC_AGAPC
AccessioniPrimary (citable) accession number: B3EWI3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 15, 2012
Last sequence update: May 15, 2012
Last modified: September 30, 2014
This is version 4 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.