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Agaricus placomyces (Mushroom)
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli


Lignin degradation and detoxification of lignin-derived products.By similarity

Catalytic activityi

4 benzenediol + O2 = 4 benzosemiquinone + 2 H2O.1 Publication


  1. KM=0.392 mM for hydroquinone1 Publication
  2. KM=0.775 mM for ABTS1 Publication

    pH dependencei

    Optimum pH is 5.2 with ABTS as substrate. Optimum pH is 6.8 with hydroquinone as substrate.1 Publication

    Temperature dependencei

    Optimum temperature is 30 degrees Celsius.1 Publication

    GO - Molecular functioni

    GO - Biological processi


    Molecular functionOxidoreductase
    Biological processLignin degradation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Laccase1 Publication (EC: Publication)
    OrganismiAgaricus placomyces (Mushroom)
    Taxonomic identifieri182818 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaBasidiomycotaAgaricomycotinaAgaricomycetesAgaricomycetidaeAgaricalesAgaricaceaeAgaricus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    ChainiPRO_00004174511 – ›15LaccaseAdd BLAST›15


    Sequence statusi: Fragment.

    Mass (Da):1,569
    Last modified:May 16, 2012 - v1

    Experimental Info

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    Non-terminal residuei151 Publication1

    Similar proteinsi

    Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
    100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
    90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
    50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

    Entry informationi

    Entry nameiLAC_AGAPC
    AccessioniPrimary (citable) accession number: B3EWI3
    Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 16, 2012
    Last sequence update: May 16, 2012
    Last modified: October 1, 2014
    This is version 4 of the entry and version 1 of the sequence. See complete history.
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program


    Keywords - Technical termi

    Direct protein sequencing