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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Amoebophilus asiaticus (strain 5a2)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei145GTPUniRule annotation1
Binding sitei149GTPUniRule annotation1
Binding sitei192GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi26 – 30GTPUniRule annotation5
Nucleotide bindingi114 – 116GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, SeptationUniRule annotation
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciCAMO452471:G1GCB-1250-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotation
Ordered Locus Names:Aasi_1249Imported
OrganismiAmoebophilus asiaticus (strain 5a2)Imported
Taxonomic identifieri452471 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesCytophagiaCytophagalesAmoebophilaceaeCandidatus Amoebophilus
Proteomesi
  • UP000001227 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi452471.Aasi_1249

Structurei

3D structure databases

ProteinModelPortaliB3ETL9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini18 – 210TubulinInterPro annotationAdd BLAST193
Domaini212 – 332Tubulin_CInterPro annotationAdd BLAST121

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CDK Bacteria
COG0206 LUCA
HOGENOMiHOG000049094
KOiK03531
OMAiIMNQGGV
OrthoDBiPOG091H02KK

Family and domain databases

CDDicd02201 FtsZ_type1, 1 hit
Gene3Di3.30.1330.20, 1 hit
3.40.50.1440, 1 hit
HAMAPiMF_00909 FtsZ, 1 hit
InterProiView protein in InterPro
IPR000158 Cell_div_FtsZ
IPR020805 Cell_div_FtsZ_CS
IPR024757 FtsZ_C
IPR008280 Tub_FtsZ_C
IPR018316 Tubulin/FtsZ_2-layer-sand-dom
IPR037103 Tubulin/FtsZ_C_sf
IPR036525 Tubulin/FtsZ_GTPase_sf
IPR003008 Tubulin_FtsZ_GTPase
PfamiView protein in Pfam
PF12327 FtsZ_C, 1 hit
PF00091 Tubulin, 1 hit
PRINTSiPR00423 CELLDVISFTSZ
SMARTiView protein in SMART
SM00864 Tubulin, 1 hit
SM00865 Tubulin_C, 1 hit
SUPFAMiSSF52490 SSF52490, 1 hit
SSF55307 SSF55307, 1 hit
TIGRFAMsiTIGR00065 ftsZ, 1 hit
PROSITEiView protein in PROSITE
PS01134 FTSZ_1, 1 hit
PS01135 FTSZ_2, 1 hit

Sequencei

Sequence statusi: Complete.

B3ETL9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MESSTHRFDL SAKPKKSIIK VIGVGGGGSN AVNSMYKHGI QDVAFIVCNT
60 70 80 90 100
DEQALKSSPI QHKLQIGINL TSGLGAGANP EVGKNAAIES KEEIEALLND
110 120 130 140 150
GTKMLFVTAG MGGGTGTGAA PVIASIANKL GILTVGIVTL PFGFEGKRKL
160 170 180 190 200
LQAQAGIKEL RQHCDTVLVI LNDRLREVLG NLSIGNAFAQ ADNVLTTAAK
210 220 230 240 250
SIAEIITVPG YVNVDFEDVK TVMKKAGAAV MGSAQAEGKD RARKAAELAL
260 270 280 290 300
TSPLLDYKDI HGAKKILLSI VSGQEAEMHM DELAIITDYI QEKVGEDAEM
310 320 330 340 350
IFGHGSDKQL KESIRVTVIA TGFDEDKEVT TRNNTTTKAE QKASTVKTAQ
360 370 380 390 400
GHLFSGFSSA EEEENKLGEQ KYKYDVTKRP AAHSHIKNTS RKSTSDIRQV
410 420 430 440 450
SNIPSLPFGV LEEKKQLLRE RAQDRVRKLA QHQASNLSEE TLKEYLDVPA
460 470 480
YLRRDVQLEE MPDVAEKDII RHYLSDQADR DTEERHNL
Length:488
Mass (Da):53,070
Last modified:July 22, 2008 - v1
Checksum:iF43574C247735552
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001102 Genomic DNA Translation: ACE06571.1
RefSeqiWP_012473326.1, NC_010830.1

Genome annotation databases

EnsemblBacteriaiACE06571; ACE06571; Aasi_1249
KEGGiaas:Aasi_1249

Similar proteinsi

Entry informationi

Entry nameiB3ETL9_AMOA5
AccessioniPrimary (citable) accession number: B3ETL9
Entry historyiIntegrated into UniProtKB/TrEMBL: July 22, 2008
Last sequence update: July 22, 2008
Last modified: March 28, 2018
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health