Reviewed, UniProtKB/Swiss-Prot B3ERZ8 (SYR_AMOA5)

Names and origin

Protein names

Recommended name:
    Arginyl-tRNA synthetase
    EC=6.1.1.19
Alternative name(s):
    Arginine--tRNA ligase
      Short name=ArgRS

Gene names

Name:	argS
Ordered Locus Names:	Aasi_0599

Organism

Amoebophilus asiaticus (strain 5a2) [Complete proteome] [HAMAP]

Taxonomic identifier

452471 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Candidatus Amoebophilus

Protein attributes

Sequence length	596 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP MF_00123
Subunit structure	Monomer By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arginyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP arginine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 596	596	Arginyl-tRNA synthetase HAMAP MF_00123		PRO_1000095332
Regions
	Motif	123 – 133	11	"HIGH" region HAMAP MF_00123

Sequences

	Sequence		Length	Mass (Da)
	B3ERZ8-1 [UniParc]. Last modified July 22, 2008. Version 1. Checksum: B43FCCE03112DB49	FASTA	596	67,709
	10 20 30 40 50 60 MNIDLVLREA IQNAFQSVFE LSIPLADVNL QPTRKEFEGT HTLIVFPFTT TCKVSPEVIA 70 80 90 100 110 120 NKIGDWMQTN TQAIASYNVV KGFLNLSIKD TIWLASFNQM YQNKHFGYLP SNRQKIVVEY 130 140 150 160 170 180 SSPNTNKPLH LGHLRNNFLG HAVSEILQAA GYEVYKVNLV NDRGIHICKS MVAYQHWGRG 190 200 210 220 230 240 ETPESRGLKG DQLVGKYYVK FDQVYKEQVA ALTQTLGDAE QAAKQAPLLQ EAQVMLKQWE 250 260 270 280 290 300 AGNEEVLALW RKMNGWVYDG FDITYQKLGI TFDKVYYESQ TYLLGKEVVA EGLAKGTFYK 310 320 330 340 350 360 KQDGSVWIDL TQEGLDEKLL LRADGTSVYI TQDLGTADLR YQDFKPNKLV YVVGNEQDYH 370 380 390 400 410 420 FEVLAKIMAR LGRPYATDLY HLSYGMVDLP TGKMKSREGT VVDADMLIDE MIETAEEHTR 430 440 450 460 470 480 ELGKIDGFSK EEAKDLYHIL AMGALKYFLL RVDAKKRLLF DPQASIDFQG DTGPFIQYTH 490 500 510 520 530 540 ARIAAVLRKV QQADIAFNDI VEQENFVLHP LEREVIVELA AFPKKLQESA LAYAPAILAQ 550 560 570 580 590 HVLEIAKAYN RMYAELSILH EQDTKVQLFR IQLSVLVAQV IKTVMHLLGI VVPERM

References

[1]

"Complete sequence of Candidatus Amoebophilus asiaticus 5a2." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Lang D., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Horn M., Richardson P. Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP001102 Genomic DNA. Translation: ACE06000.1.
RefSeq	YP_001957729.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	6376447.
GenomeReviews	Gene locus Aasi_0599 in contig CP001102_GR.
KEGG	aas:Aasi_0599.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	YTHARIA.
Family and domain databases
HAMAP	MF_00123. [Tree]
InterPro	IPR001412. aa-tRNA-synth_I_CS. IPR001278. Arg-tRNA-synth_Ic. IPR015945. Arg-tRNA-synth_Ic_core. IPR005148. Arg-tRNA-synth_Ic_N. IPR008909. DALR_anticod_bd. IPR014729. Rossmann-like_a/b/a_fold. [Graphical view]
Gene3D	G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit.
PANTHER	PTHR11956. Arg_tRNA-synt_1c. 1 hit.
Pfam	PF03485. Arg_tRNA_synt_N. 1 hit. PF05746. DALR_1. 1 hit. PF00750. tRNA-synt_1d. 1 hit. [Graphical view]
PRINTS	PR01038. TRNASYNTHARG.
TIGRFAMs	TIGR00456. argS. 1 hit.
PROSITE	PS00178. AA_TRNA_LIGASE_I. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYR_AMOA5

Accession

Primary (citable) accession number: B3ERZ8

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	July 22, 2008
Last modified:	November 3, 2009
This is version 10 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)