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B3ERZ8 (SYR_AMOA5) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 39. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:Aasi_0599
OrganismAmoebophilus asiaticus (strain 5a2) [Complete proteome] [HAMAP]
Taxonomic identifier452471 [NCBI]
Taxonomic lineageBacteriaBacteroidetesCandidatus Amoebophilus

Protein attributes

Sequence length596 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 596596Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_1000095332

Regions

Motif123 – 13311"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
B3ERZ8 [UniParc].

Last modified July 22, 2008. Version 1.
Checksum: B43FCCE03112DB49

FASTA59667,709
        10         20         30         40         50         60 
MNIDLVLREA IQNAFQSVFE LSIPLADVNL QPTRKEFEGT HTLIVFPFTT TCKVSPEVIA 

        70         80         90        100        110        120 
NKIGDWMQTN TQAIASYNVV KGFLNLSIKD TIWLASFNQM YQNKHFGYLP SNRQKIVVEY 

       130        140        150        160        170        180 
SSPNTNKPLH LGHLRNNFLG HAVSEILQAA GYEVYKVNLV NDRGIHICKS MVAYQHWGRG 

       190        200        210        220        230        240 
ETPESRGLKG DQLVGKYYVK FDQVYKEQVA ALTQTLGDAE QAAKQAPLLQ EAQVMLKQWE 

       250        260        270        280        290        300 
AGNEEVLALW RKMNGWVYDG FDITYQKLGI TFDKVYYESQ TYLLGKEVVA EGLAKGTFYK 

       310        320        330        340        350        360 
KQDGSVWIDL TQEGLDEKLL LRADGTSVYI TQDLGTADLR YQDFKPNKLV YVVGNEQDYH 

       370        380        390        400        410        420 
FEVLAKIMAR LGRPYATDLY HLSYGMVDLP TGKMKSREGT VVDADMLIDE MIETAEEHTR 

       430        440        450        460        470        480 
ELGKIDGFSK EEAKDLYHIL AMGALKYFLL RVDAKKRLLF DPQASIDFQG DTGPFIQYTH 

       490        500        510        520        530        540 
ARIAAVLRKV QQADIAFNDI VEQENFVLHP LEREVIVELA AFPKKLQESA LAYAPAILAQ 

       550        560        570        580        590 
HVLEIAKAYN RMYAELSILH EQDTKVQLFR IQLSVLVAQV IKTVMHLLGI VVPERM 

« Hide

References

[1]"Complete sequence of Candidatus Amoebophilus asiaticus 5a2."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Lang D., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Horn M., Richardson P.
Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 5a2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001102 Genomic DNA. Translation: ACE06000.1.
RefSeqYP_001957729.1. NC_010830.1.

3D structure databases

ProteinModelPortalB3ERZ8.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING452471.Aasi_0599.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACE06000; ACE06000; Aasi_0599.
GeneID6376447.
KEGGaas:Aasi_0599.
PATRIC21266675. VBICanAmo76781_0684.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247211.
KOK01887.
OMADGTAVYM.
OrthoDBEOG6JB13C.
ProtClustDBPRK01611.

Enzyme and pathway databases

BioCycAASI452471:GKEN-656-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_AMOA5
AccessionPrimary (citable) accession number: B3ERZ8
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: July 22, 2008
Last modified: April 16, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries