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B3ERA3 (B3ERA3_AMOA5) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha HAMAP MF_00823
Short name=ACCase subunit alpha HAMAP MF_00823
Short name=Acetyl-CoA carboxylase carboxyltransferase subunit alpha HAMAP MF_00823
EC=6.4.1.2 HAMAP MF_00823
Gene names
Name:accA HAMAP MF_00823
Ordered Locus Names:Aasi_0321
OrganismAmoebophilus asiaticus (strain 5a2) [Complete proteome] [HAMAP]
Taxonomic identifier452471 [NCBI]
Taxonomic lineageBacteria › Bacteroidetes › Candidatus Amoebophilus

Protein attributes

Sequence length316 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO2 group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA By similarity. HAMAP MF_00823 SAAS SAAS011763

Catalytic activity

ATP + acetyl-CoA + HCO3- = ADP + phosphate + malonyl-CoA. HAMAP MF_00823 SAAS SAAS011763

Pathway

Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1. HAMAP MF_00823 SAAS SAAS011763

Subunit structure

Acetyl-CoA carboxylase is an heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD) By similarity. HAMAP MF_00823 SAAS SAAS011763

Subcellular location

Cytoplasm By similarity HAMAP MF_00823 SAAS SAAS011763.

Sequence similarities

Belongs to the AccA family. HAMAP MF_00823

Sequences

Sequence LengthMass (Da)Tools
B3ERA3 [UniParc].

Last modified July 22, 2008. Version 1.
Checksum: 982D55AEFEE53CB1

FASTA31635,479
        10         20         30         40         50         60 
MLLEFEKPIA LLEEKLAAMK AKAAQRKASK LLQPIQKLEE QIKTLQAETF KNLTPWQRVQ 

        70         80         90        100        110        120 
LSRHADRPYT LDYITHMTND FISLHGDRTG KDDPAIVGGF ARLDNQTIML IGHQKGRTTK 

       130        140        150        160        170        180 
ERQARNFGMA NPEGYRKALR LMKLAEKFNK PIVTLIDTPG AYPGLEAEEH GQAEAIAKNI 

       190        200        210        220        230        240 
QSMFDIRVPI ICIIIGEGAS GGALGIAVGD RILMLENTWY SVISPESCAS ILWKSWDYKE 

       250        260        270        280        290        300 
QAAEVLKLTA ADMQKLNLID GIIAEPLGGA HRNPQEIALT VKTEILKQLE TLNKVKSDKR 

       310 
MEERIEKFCK MGMVKE

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References

[1]"Complete sequence of Candidatus Amoebophilus asiaticus 5a2."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Lang D., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Horn M., Richardson P.
Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 5a2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001102 Genomic DNA. Translation: ACE05755.1.
RefSeqYP_001957484.1. NC_010830.1.

3D structure databases

ProteinModelPortalB3ERA3.
ModBaseSearch...

Protein-protein interaction databases

STRINGB3ERA3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6377732.
GenomeReviewsGene locus Aasi_0321 in contig CP001102_GR.
KEGGaas:Aasi_0321.
PATRIC21266006. VBICanAmo76781_0361.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG286557.
OMAGRDTKDN.

Family and domain databases

HAMAPMF_00823. AcetylCoA_CT_alpha.
[Tree]
InterProIPR001095. Acetyl_CoA_COase_a_su.
IPR011763. COA_CT_C.
[Graphical view]
KOK01962.
PANTHERPTHR22855:SF3. Ac-CoA_carboxylA. 1 hit.
PfamPF03255. ACCA. 1 hit.
[Graphical view]
PRINTSPR01069. ACCCTRFRASEA.
TIGRFAMsTIGR00513. AccA. 1 hit.
PROSITEPS50989. COA_CT_CTER. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB3ERA3_AMOA5
AccessionPrimary (citable) accession number: B3ERA3
Entry history
Integrated into UniProtKB/TrEMBL: July 22, 2008
Last sequence update: July 22, 2008
Last modified: December 14, 2011
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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