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B3EMU5 (B3EMU5_CHLPB) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Dihydroorotate dehydrogenase HAMAP MF_00224
Short name=DHOD HAMAP MF_00224
Short name=DHODase HAMAP MF_00224
Short name=DHOdehase HAMAP MF_00224
EC=1.3.-.- HAMAP MF_00224
Gene names
Name:pyrD HAMAP MF_00224
Ordered Locus Names:Cphamn1_0614
OrganismChlorobium phaeobacteroides (strain BS1) [Complete proteome] [HAMAP]
Taxonomic identifier331678 [NCBI]
Taxonomic lineageBacteria › Chlorobi › Chlorobia › Chlorobiales › Chlorobiaceae › Chlorobium/Pelodictyon group › Chlorobium

Protein attributes

Sequence length314 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the conversion of dihydroorotate to orotate By similarity. HAMAP MF_00224

Catalytic activity

(S)-dihydroorotate + acceptor = orotate + reduced acceptor. HAMAP MF_00224

Cofactor

Binds 1 FMN per subunit By similarity. HAMAP MF_00224 SAAS SAAS012135

Pathway

Pyrimidine metabolism; UMP biosynthesis via de novo pathway. HAMAP MF_00224

Subcellular location

Cytoplasm By similarity HAMAP MF_00224.

Sequence similarities

Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily. HAMAP MF_00224

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1401Nucleophile By similarity PIRSR PIRSR000164-1

Sequences

Sequence LengthMass (Da)Tools
B3EMU5 [UniParc].

Last modified July 22, 2008. Version 1.
Checksum: 458ADE222E1257BB

FASTA31433,402
        10         20         30         40         50         60 
MTKNPEQHSS RYAALSLGRG LDLRSPVLLA SGTVSYGEEL NMLTDLEKIG GIVTKAISPE 

        70         80         90        100        110        120 
PREGNPPQRI AETPCGMINA IGLANVGLDR FVEDKIPFLQ QLDTGVIVNI AGKSIDDYCT 

       130        140        150        160        170        180 
VIERLESSED ISAYEINLSC PNVKGECMIM GVSSTATFEI ISKLRTLTER HLMVKLTPNV 

       190        200        210        220        230        240 
TSISAIAIAA EDAGADSVSL INTLVGMAID YKTRKPLLKN VTGGLSGPAI KPVALAKVWE 

       250        260        270        280        290        300 
VYNAVKIPVV GMGGISSFKD AMEFLLAGAS AIQIGTMNFV DPDIGETVAN AIEEFFADPV 

       310 
NPSLREYVGS LIVG

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References

[1]"Complete sequence of Chlorobium phaeobacteroides BS1."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Li T., Liu Z., Zhao F. expand/collapse author list , Overmann J., Bryant D.A., Richardson P.
Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: BS1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001101 Genomic DNA. Translation: ACE03573.1.
RefSeqYP_001959054.1. NC_010831.1.

3D structure databases

ProteinModelPortalB3EMU5.
ModBaseSearch...

Protein-protein interaction databases

STRINGB3EMU5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6374278.
GenomeReviewsGene locus Cphamn1_0614 in contig CP001101_GR.
KEGGcpb:Cphamn1_0614.
PATRIC21383296. VBIChlPha121022_0658.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG472415.
OMAVALRMVW.
ProtClustDBCLSK637846.

Family and domain databases

HAMAPMF_00224. DHO_dh_type1.
[Tree]
InterProIPR013785. Aldolase_TIM.
IPR005720. Dihydroorotate_DH.
IPR024920. Dihydroorotate_DH_1.
IPR012135. Dihydroorotate_DH_1_2.
IPR001295. Dihydroorotate_DH_CS.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK00226.
PfamPF01180. DHO_dh. 1 hit.
[Graphical view]
PIRSFPIRSF000164. DHO_oxidase. 1 hit.
TIGRFAMsTIGR01037. PyrD_sub1_fam. 1 hit.
PROSITEPS00912. DHODEHASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB3EMU5_CHLPB
AccessionPrimary (citable) accession number: B3EMU5
Entry history
Integrated into UniProtKB/TrEMBL: July 22, 2008
Last sequence update: July 22, 2008
Last modified: January 25, 2012
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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