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B3EMN6

- PNP_CHLPB

UniProt

B3EMN6 - PNP_CHLPB

Protein

Polyribonucleotide nucleotidyltransferase

Gene

pnp

Organism
Chlorobium phaeobacteroides (strain BS1)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 46 (01 Oct 2014)
      Sequence version 1 (22 Jul 2008)
      Previous versions | rss
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    Functioni

    Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.UniRule annotation

    Catalytic activityi

    RNA(n+1) + phosphate = RNA(n) + a nucleoside diphosphate.UniRule annotation

    Cofactori

    Magnesium.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi503 – 5031MagnesiumUniRule annotation
    Metal bindingi509 – 5091MagnesiumUniRule annotation

    GO - Molecular functioni

    1. 3'-5'-exoribonuclease activity Source: InterPro
    2. magnesium ion binding Source: UniProtKB-HAMAP
    3. polyribonucleotide nucleotidyltransferase activity Source: UniProtKB-HAMAP
    4. RNA binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. mRNA catabolic process Source: UniProtKB-HAMAP
    2. RNA processing Source: InterPro

    Keywords - Molecular functioni

    Nucleotidyltransferase, Transferase

    Keywords - Ligandi

    Magnesium, Metal-binding, RNA-binding

    Enzyme and pathway databases

    BioCyciCPHA331678:GHME-574-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Polyribonucleotide nucleotidyltransferaseUniRule annotation (EC:2.7.7.8UniRule annotation)
    Alternative name(s):
    Polynucleotide phosphorylaseUniRule annotation
    Short name:
    PNPaseUniRule annotation
    Gene namesi
    Name:pnpUniRule annotation
    Ordered Locus Names:Cphamn1_0552
    OrganismiChlorobium phaeobacteroides (strain BS1)
    Taxonomic identifieri331678 [NCBI]
    Taxonomic lineageiBacteriaChlorobiChlorobiaChlorobialesChlorobiaceaeChlorobium/Pelodictyon groupChlorobium
    ProteomesiUP000001228: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 734734Polyribonucleotide nucleotidyltransferasePRO_1000147901Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi331678.Cphamn1_0552.

    Structurei

    3D structure databases

    ProteinModelPortaliB3EMN6.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini570 – 62960KHUniRule annotationAdd
    BLAST
    Domaini639 – 71375S1 motifUniRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the polyribonucleotide nucleotidyltransferase family.UniRule annotation
    Contains 1 KH domain.UniRule annotation
    Contains 1 S1 motif domain.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1185.
    HOGENOMiHOG000218326.
    KOiK00962.
    OMAiGTENTIC.
    OrthoDBiEOG6WT8CC.

    Family and domain databases

    Gene3Di1.10.10.400. 1 hit.
    2.40.50.140. 1 hit.
    3.30.1370.10. 1 hit.
    3.30.230.70. 2 hits.
    HAMAPiMF_01595. PNPase.
    InterProiIPR001247. ExoRNase_PH_dom1.
    IPR015847. ExoRNase_PH_dom2.
    IPR004087. KH_dom.
    IPR004088. KH_dom_type_1.
    IPR012340. NA-bd_OB-fold.
    IPR012162. PNPase.
    IPR027408. PNPase/RNase_PH_dom.
    IPR015848. PNPase_PH_RNA-bd_bac/org-type.
    IPR003029. Rbsml_prot_S1_RNA-bd_dom.
    IPR020568. Ribosomal_S5_D2-typ_fold.
    IPR022967. RNA-binding_domain_S1.
    [Graphical view]
    PANTHERiPTHR11252. PTHR11252. 1 hit.
    PfamiPF00013. KH_1. 1 hit.
    PF03726. PNPase. 1 hit.
    PF01138. RNase_PH. 2 hits.
    PF03725. RNase_PH_C. 2 hits.
    PF00575. S1. 1 hit.
    [Graphical view]
    PIRSFiPIRSF005499. PNPase. 1 hit.
    SMARTiSM00322. KH. 1 hit.
    SM00316. S1. 1 hit.
    [Graphical view]
    SUPFAMiSSF50249. SSF50249. 1 hit.
    SSF54211. SSF54211. 2 hits.
    SSF54791. SSF54791. 1 hit.
    SSF55666. SSF55666. 2 hits.
    TIGRFAMsiTIGR03591. polynuc_phos. 1 hit.
    PROSITEiPS50084. KH_TYPE_1. 1 hit.
    PS50126. S1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B3EMN6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MFIRKEIDLG DGKVITIETG KMAKQADGAT IVRMGDTMVI ATVVSSRTPP    50
    SPNQDFFPMQ VEYREKYYAA GKFPGGFIKR ESRPSEKEIL SARLIDRALR 100
    PLFPNGYYQD TQIIISVISS DQLNDADVLG GIAASAAIMV SDIPFANSMS 150
    EVRVGRINGE FVINPTINEL AQSDIDISIG GTNDTICMLE GEMNEISEAE 200
    MLEAIRFGHE AIKKICSLQD DIAAEVNKPK RSFLAIDAPD ELKESIKEAC 250
    EAPLKELAYM PLAKEERAEK TTAVYKSITE QILGRYKNEI TAEDIAADPS 300
    KALYLNEQII SGHIHAIEKQ VMRHMILDDA KRLDGRKLEE VRPISIELGL 350
    IPRAHGSALF TRGETQALVV LTLGTKKDAQ MIDTLLDDTE KRFMLHYNFP 400
    PFSVGETGRV GGVGRREIGH GNLAERAVKK VVPSESEFPY TIRLVSEILE 450
    SNGSSSMASV CGATLAAMDG GVPLTKPVSG IAMGLIKEDD NYAVLSDILG 500
    NEDHLGDMDF KVAGTRDGIT ACQMDIKIDG LDYHILEKAL EQSKNGRLHI 550
    LDKMTESIAD PRGEIGQYAP KLSTIQVPVD AIGMIIGKGG ETIRSITEET 600
    GAQINVDDDG TVTISSPNGE SAAAAIETIK TLISKPEVGT IYMGKVKDIR 650
    EDLGAFVEIL PRTDGLVHIS EIARERVNKV SDHLKQGDRV KVKLIDIRKD 700
    QRSGKIRYAL SIKALLDMPA ESANGPSAQE EQNQ 734
    Length:734
    Mass (Da):80,167
    Last modified:July 22, 2008 - v1
    Checksum:i637E7CC1A3BD92ED
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001101 Genomic DNA. Translation: ACE03514.1.
    RefSeqiWP_012474005.1. NC_010831.1.
    YP_001958995.1. NC_010831.1.

    Genome annotation databases

    EnsemblBacteriaiACE03514; ACE03514; Cphamn1_0552.
    GeneIDi6374216.
    KEGGicpb:Cphamn1_0552.
    PATRICi21383172. VBIChlPha121022_0596.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001101 Genomic DNA. Translation: ACE03514.1 .
    RefSeqi WP_012474005.1. NC_010831.1.
    YP_001958995.1. NC_010831.1.

    3D structure databases

    ProteinModelPortali B3EMN6.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 331678.Cphamn1_0552.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACE03514 ; ACE03514 ; Cphamn1_0552 .
    GeneIDi 6374216.
    KEGGi cpb:Cphamn1_0552.
    PATRICi 21383172. VBIChlPha121022_0596.

    Phylogenomic databases

    eggNOGi COG1185.
    HOGENOMi HOG000218326.
    KOi K00962.
    OMAi GTENTIC.
    OrthoDBi EOG6WT8CC.

    Enzyme and pathway databases

    BioCyci CPHA331678:GHME-574-MONOMER.

    Family and domain databases

    Gene3Di 1.10.10.400. 1 hit.
    2.40.50.140. 1 hit.
    3.30.1370.10. 1 hit.
    3.30.230.70. 2 hits.
    HAMAPi MF_01595. PNPase.
    InterProi IPR001247. ExoRNase_PH_dom1.
    IPR015847. ExoRNase_PH_dom2.
    IPR004087. KH_dom.
    IPR004088. KH_dom_type_1.
    IPR012340. NA-bd_OB-fold.
    IPR012162. PNPase.
    IPR027408. PNPase/RNase_PH_dom.
    IPR015848. PNPase_PH_RNA-bd_bac/org-type.
    IPR003029. Rbsml_prot_S1_RNA-bd_dom.
    IPR020568. Ribosomal_S5_D2-typ_fold.
    IPR022967. RNA-binding_domain_S1.
    [Graphical view ]
    PANTHERi PTHR11252. PTHR11252. 1 hit.
    Pfami PF00013. KH_1. 1 hit.
    PF03726. PNPase. 1 hit.
    PF01138. RNase_PH. 2 hits.
    PF03725. RNase_PH_C. 2 hits.
    PF00575. S1. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF005499. PNPase. 1 hit.
    SMARTi SM00322. KH. 1 hit.
    SM00316. S1. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50249. SSF50249. 1 hit.
    SSF54211. SSF54211. 2 hits.
    SSF54791. SSF54791. 1 hit.
    SSF55666. SSF55666. 2 hits.
    TIGRFAMsi TIGR03591. polynuc_phos. 1 hit.
    PROSITEi PS50084. KH_TYPE_1. 1 hit.
    PS50126. S1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: BS1.

    Entry informationi

    Entry nameiPNP_CHLPB
    AccessioniPrimary (citable) accession number: B3EMN6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 14, 2009
    Last sequence update: July 22, 2008
    Last modified: October 1, 2014
    This is version 46 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3