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B3EMN6

- PNP_CHLPB

UniProt

B3EMN6 - PNP_CHLPB

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Protein
Polyribonucleotide nucleotidyltransferase
Gene
pnp, Cphamn1_0552
Organism
Chlorobium phaeobacteroides (strain BS1)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction By similarity.UniRule annotation

Catalytic activityi

RNA(n+1) + phosphate = RNA(n) + a nucleoside diphosphate.UniRule annotation

Cofactori

Magnesium By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi503 – 5031Magnesium By similarity
Metal bindingi509 – 5091Magnesium By similarity

GO - Molecular functioni

  1. 3'-5'-exoribonuclease activity Source: InterPro
  2. RNA binding Source: UniProtKB-HAMAP
  3. magnesium ion binding Source: UniProtKB-HAMAP
  4. polyribonucleotide nucleotidyltransferase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. RNA processing Source: InterPro
  2. mRNA catabolic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Ligandi

Magnesium, Metal-binding, RNA-binding

Enzyme and pathway databases

BioCyciCPHA331678:GHME-574-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Polyribonucleotide nucleotidyltransferase (EC:2.7.7.8)
Alternative name(s):
Polynucleotide phosphorylase
Short name:
PNPase
Gene namesi
Name:pnp
Ordered Locus Names:Cphamn1_0552
OrganismiChlorobium phaeobacteroides (strain BS1)
Taxonomic identifieri331678 [NCBI]
Taxonomic lineageiBacteriaChlorobiChlorobiaChlorobialesChlorobiaceaeChlorobium/Pelodictyon groupChlorobium
ProteomesiUP000001228: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 734734Polyribonucleotide nucleotidyltransferaseUniRule annotation
PRO_1000147901Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi331678.Cphamn1_0552.

Structurei

3D structure databases

ProteinModelPortaliB3EMN6.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini570 – 62960KH
Add
BLAST
Domaini639 – 71375S1 motif
Add
BLAST

Sequence similaritiesi

Contains 1 KH domain.
Contains 1 S1 motif domain.

Phylogenomic databases

eggNOGiCOG1185.
HOGENOMiHOG000218326.
KOiK00962.
OMAiGTENTIC.
OrthoDBiEOG6WT8CC.

Family and domain databases

Gene3Di1.10.10.400. 1 hit.
2.40.50.140. 1 hit.
3.30.1370.10. 1 hit.
3.30.230.70. 2 hits.
HAMAPiMF_01595. PNPase.
InterProiIPR001247. ExoRNase_PH_dom1.
IPR015847. ExoRNase_PH_dom2.
IPR004087. KH_dom.
IPR004088. KH_dom_type_1.
IPR012340. NA-bd_OB-fold.
IPR012162. PNPase.
IPR027408. PNPase/RNase_PH_dom.
IPR015848. PNPase_PH_RNA-bd_bac/org-type.
IPR003029. Rbsml_prot_S1_RNA-bd_dom.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR022967. RNA-binding_domain_S1.
[Graphical view]
PANTHERiPTHR11252. PTHR11252. 1 hit.
PfamiPF00013. KH_1. 1 hit.
PF03726. PNPase. 1 hit.
PF01138. RNase_PH. 2 hits.
PF03725. RNase_PH_C. 2 hits.
PF00575. S1. 1 hit.
[Graphical view]
PIRSFiPIRSF005499. PNPase. 1 hit.
SMARTiSM00322. KH. 1 hit.
SM00316. S1. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
SSF54211. SSF54211. 2 hits.
SSF54791. SSF54791. 1 hit.
SSF55666. SSF55666. 2 hits.
TIGRFAMsiTIGR03591. polynuc_phos. 1 hit.
PROSITEiPS50084. KH_TYPE_1. 1 hit.
PS50126. S1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B3EMN6-1 [UniParc]FASTAAdd to Basket

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MFIRKEIDLG DGKVITIETG KMAKQADGAT IVRMGDTMVI ATVVSSRTPP    50
SPNQDFFPMQ VEYREKYYAA GKFPGGFIKR ESRPSEKEIL SARLIDRALR 100
PLFPNGYYQD TQIIISVISS DQLNDADVLG GIAASAAIMV SDIPFANSMS 150
EVRVGRINGE FVINPTINEL AQSDIDISIG GTNDTICMLE GEMNEISEAE 200
MLEAIRFGHE AIKKICSLQD DIAAEVNKPK RSFLAIDAPD ELKESIKEAC 250
EAPLKELAYM PLAKEERAEK TTAVYKSITE QILGRYKNEI TAEDIAADPS 300
KALYLNEQII SGHIHAIEKQ VMRHMILDDA KRLDGRKLEE VRPISIELGL 350
IPRAHGSALF TRGETQALVV LTLGTKKDAQ MIDTLLDDTE KRFMLHYNFP 400
PFSVGETGRV GGVGRREIGH GNLAERAVKK VVPSESEFPY TIRLVSEILE 450
SNGSSSMASV CGATLAAMDG GVPLTKPVSG IAMGLIKEDD NYAVLSDILG 500
NEDHLGDMDF KVAGTRDGIT ACQMDIKIDG LDYHILEKAL EQSKNGRLHI 550
LDKMTESIAD PRGEIGQYAP KLSTIQVPVD AIGMIIGKGG ETIRSITEET 600
GAQINVDDDG TVTISSPNGE SAAAAIETIK TLISKPEVGT IYMGKVKDIR 650
EDLGAFVEIL PRTDGLVHIS EIARERVNKV SDHLKQGDRV KVKLIDIRKD 700
QRSGKIRYAL SIKALLDMPA ESANGPSAQE EQNQ 734
Length:734
Mass (Da):80,167
Last modified:July 22, 2008 - v1
Checksum:i637E7CC1A3BD92ED
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001101 Genomic DNA. Translation: ACE03514.1.
RefSeqiWP_012474005.1. NC_010831.1.
YP_001958995.1. NC_010831.1.

Genome annotation databases

EnsemblBacteriaiACE03514; ACE03514; Cphamn1_0552.
GeneIDi6374216.
KEGGicpb:Cphamn1_0552.
PATRICi21383172. VBIChlPha121022_0596.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001101 Genomic DNA. Translation: ACE03514.1 .
RefSeqi WP_012474005.1. NC_010831.1.
YP_001958995.1. NC_010831.1.

3D structure databases

ProteinModelPortali B3EMN6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 331678.Cphamn1_0552.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACE03514 ; ACE03514 ; Cphamn1_0552 .
GeneIDi 6374216.
KEGGi cpb:Cphamn1_0552.
PATRICi 21383172. VBIChlPha121022_0596.

Phylogenomic databases

eggNOGi COG1185.
HOGENOMi HOG000218326.
KOi K00962.
OMAi GTENTIC.
OrthoDBi EOG6WT8CC.

Enzyme and pathway databases

BioCyci CPHA331678:GHME-574-MONOMER.

Family and domain databases

Gene3Di 1.10.10.400. 1 hit.
2.40.50.140. 1 hit.
3.30.1370.10. 1 hit.
3.30.230.70. 2 hits.
HAMAPi MF_01595. PNPase.
InterProi IPR001247. ExoRNase_PH_dom1.
IPR015847. ExoRNase_PH_dom2.
IPR004087. KH_dom.
IPR004088. KH_dom_type_1.
IPR012340. NA-bd_OB-fold.
IPR012162. PNPase.
IPR027408. PNPase/RNase_PH_dom.
IPR015848. PNPase_PH_RNA-bd_bac/org-type.
IPR003029. Rbsml_prot_S1_RNA-bd_dom.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR022967. RNA-binding_domain_S1.
[Graphical view ]
PANTHERi PTHR11252. PTHR11252. 1 hit.
Pfami PF00013. KH_1. 1 hit.
PF03726. PNPase. 1 hit.
PF01138. RNase_PH. 2 hits.
PF03725. RNase_PH_C. 2 hits.
PF00575. S1. 1 hit.
[Graphical view ]
PIRSFi PIRSF005499. PNPase. 1 hit.
SMARTi SM00322. KH. 1 hit.
SM00316. S1. 1 hit.
[Graphical view ]
SUPFAMi SSF50249. SSF50249. 1 hit.
SSF54211. SSF54211. 2 hits.
SSF54791. SSF54791. 1 hit.
SSF55666. SSF55666. 2 hits.
TIGRFAMsi TIGR03591. polynuc_phos. 1 hit.
PROSITEi PS50084. KH_TYPE_1. 1 hit.
PS50126. S1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BS1.

Entry informationi

Entry nameiPNP_CHLPB
AccessioniPrimary (citable) accession number: B3EMN6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: July 22, 2008
Last modified: September 3, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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