Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

B3EMN5

- SYL_CHLPB

UniProt

B3EMN5 - SYL_CHLPB

Protein

Leucine--tRNA ligase

Gene

leuS

Organism
Chlorobium phaeobacteroides (strain BS1)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 46 (01 Oct 2014)
      Sequence version 1 (22 Jul 2008)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu).UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei579 – 5791ATPUniRule annotation

    GO - Molecular functioni

    1. aminoacyl-tRNA editing activity Source: InterPro
    2. ATP binding Source: UniProtKB-HAMAP
    3. leucine-tRNA ligase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. leucyl-tRNA aminoacylation Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Aminoacyl-tRNA synthetase, Ligase

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciCPHA331678:GHME-573-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Leucine--tRNA ligaseUniRule annotation (EC:6.1.1.4UniRule annotation)
    Alternative name(s):
    Leucyl-tRNA synthetaseUniRule annotation
    Short name:
    LeuRSUniRule annotation
    Gene namesi
    Name:leuSUniRule annotation
    Ordered Locus Names:Cphamn1_0551
    OrganismiChlorobium phaeobacteroides (strain BS1)
    Taxonomic identifieri331678 [NCBI]
    Taxonomic lineageiBacteriaChlorobiChlorobiaChlorobialesChlorobiaceaeChlorobium/Pelodictyon groupChlorobium
    ProteomesiUP000001228: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 806806Leucine--tRNA ligasePRO_1000091304Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi331678.Cphamn1_0551.

    Structurei

    3D structure databases

    ProteinModelPortaliB3EMN5.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Motif

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Motifi40 – 5112"HIGH" regionAdd
    BLAST
    Motifi576 – 5805"KMSKS" region

    Sequence similaritiesi

    Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0495.
    HOGENOMiHOG000200748.
    KOiK01869.
    OMAiERYWMNV.
    OrthoDBiEOG63Z74X.

    Family and domain databases

    Gene3Di1.10.730.10. 1 hit.
    3.40.50.620. 2 hits.
    3.90.740.10. 1 hit.
    HAMAPiMF_00049_B. Leu_tRNA_synth_B.
    InterProiIPR002300. aa-tRNA-synth_Ia.
    IPR002302. Leu-tRNA-ligase.
    IPR025709. Leu_tRNA-synth_edit.
    IPR015413. Methionyl/Leucyl_tRNA_Synth.
    IPR014729. Rossmann-like_a/b/a_fold.
    IPR009080. tRNAsynth_1a_anticodon-bd.
    IPR013155. V/L/I-tRNA-synth_anticodon-bd.
    IPR009008. Val/Leu/Ile-tRNA-synth_edit.
    [Graphical view]
    PANTHERiPTHR11946:SF7. PTHR11946:SF7. 1 hit.
    PfamiPF08264. Anticodon_1. 1 hit.
    PF00133. tRNA-synt_1. 1 hit.
    PF13603. tRNA-synt_1_2. 1 hit.
    PF09334. tRNA-synt_1g. 1 hit.
    [Graphical view]
    PRINTSiPR00985. TRNASYNTHLEU.
    SUPFAMiSSF47323. SSF47323. 1 hit.
    SSF50677. SSF50677. 1 hit.
    TIGRFAMsiTIGR00396. leuS_bact. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    B3EMN5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRYDFQSIEK KWQAYWNEHQ TFLTKETVDK PKYYVLDMFP YPSGSGLHVG    50
    HLEGYTATDI ISRYKRSRGH NVLHPMGWDA FGLPAEQFAI KTGTHPKVIT 100
    EKNVSSFKDT LMRMGFSYDW NREINTTDPG YYAWTQWIFL QLLDRGLAYT 150
    SEIDVNWCEE LKTVLANEEV AEKVADGHAV VRKPLRQWVL KITAYAERLL 200
    SDLDLVDWPE SVKQMQRNWI GRSEGVEIDF QLPCHRTSLK VYTTRPDTLF 250
    GATYLVISPE HPMAEKLATA EHLIEAKNYI EEAKRKTELE RTGLQKEKTG 300
    VFTGSFAVNP ANGQALPVWI SDFVLTSYGT GAIMSVPAHD GRDWEFAKKF 350
    DLPIVEVIKS PHDVEEAVFE EKGSVCINSS NDDISLDGLP FETSFGVMAD 400
    WLEKKGTGKR TVKYKLRDWI FSRQRYWGEP IPVKYYEDGT LRPESDLPLT 450
    LPDIEAYEPT TTGESPLANI SEWLYGTDEN GSFRRETNTM PQWAGSCWYY 500
    LRFIDPGNTE KPVDPKKEQY WMNVDLYVGG AEHAVLHLLY ARFWHKVLFD 550
    LGVVSTKEPF QKLFNQGMIL GEDNEKMSKS RGNVIPADQV LGSYGADAVR 600
    LYEMFLGPLE QVKPWNTNGI EGVSRFLSRV WRLIYPEPGS MAELNEAPLT 650
    EDLTRTMHKA VKKITDHTEQ LKFNTAISEM MVFVNELHKS GSRNRTAVET 700
    LLLLLSPYAP HICEELWEAI GHDTSITEEN WPLFDPALAA DNEVTIAVQV 750
    NGKLRGTVTA PAGSPKNILL DSARKEESVR KFLDGMSIIK EVVVPDRLVN 800
    FVVKPG 806
    Length:806
    Mass (Da):91,859
    Last modified:July 22, 2008 - v1
    Checksum:i10EA7B28DBCFAFC7
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001101 Genomic DNA. Translation: ACE03513.1.
    RefSeqiYP_001958994.1. NC_010831.1.

    Genome annotation databases

    EnsemblBacteriaiACE03513; ACE03513; Cphamn1_0551.
    GeneIDi6374215.
    KEGGicpb:Cphamn1_0551.
    PATRICi21383168. VBIChlPha121022_0594.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001101 Genomic DNA. Translation: ACE03513.1 .
    RefSeqi YP_001958994.1. NC_010831.1.

    3D structure databases

    ProteinModelPortali B3EMN5.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 331678.Cphamn1_0551.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACE03513 ; ACE03513 ; Cphamn1_0551 .
    GeneIDi 6374215.
    KEGGi cpb:Cphamn1_0551.
    PATRICi 21383168. VBIChlPha121022_0594.

    Phylogenomic databases

    eggNOGi COG0495.
    HOGENOMi HOG000200748.
    KOi K01869.
    OMAi ERYWMNV.
    OrthoDBi EOG63Z74X.

    Enzyme and pathway databases

    BioCyci CPHA331678:GHME-573-MONOMER.

    Family and domain databases

    Gene3Di 1.10.730.10. 1 hit.
    3.40.50.620. 2 hits.
    3.90.740.10. 1 hit.
    HAMAPi MF_00049_B. Leu_tRNA_synth_B.
    InterProi IPR002300. aa-tRNA-synth_Ia.
    IPR002302. Leu-tRNA-ligase.
    IPR025709. Leu_tRNA-synth_edit.
    IPR015413. Methionyl/Leucyl_tRNA_Synth.
    IPR014729. Rossmann-like_a/b/a_fold.
    IPR009080. tRNAsynth_1a_anticodon-bd.
    IPR013155. V/L/I-tRNA-synth_anticodon-bd.
    IPR009008. Val/Leu/Ile-tRNA-synth_edit.
    [Graphical view ]
    PANTHERi PTHR11946:SF7. PTHR11946:SF7. 1 hit.
    Pfami PF08264. Anticodon_1. 1 hit.
    PF00133. tRNA-synt_1. 1 hit.
    PF13603. tRNA-synt_1_2. 1 hit.
    PF09334. tRNA-synt_1g. 1 hit.
    [Graphical view ]
    PRINTSi PR00985. TRNASYNTHLEU.
    SUPFAMi SSF47323. SSF47323. 1 hit.
    SSF50677. SSF50677. 1 hit.
    TIGRFAMsi TIGR00396. leuS_bact. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: BS1.

    Entry informationi

    Entry nameiSYL_CHLPB
    AccessioniPrimary (citable) accession number: B3EMN5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 24, 2009
    Last sequence update: July 22, 2008
    Last modified: October 1, 2014
    This is version 46 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Aminoacyl-tRNA synthetases
      List of aminoacyl-tRNA synthetase entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3