B3EM34 (B3EM34_CHLPB) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Lipid-A-disaccharide synthase EMBL ACE03412.1
EC=2.4.1.182 EMBL ACE03412.1

Gene names

Ordered Locus Names:

Cphamn1_0448

Organism

Chlorobium phaeobacteroides (strain BS1) [Complete proteome] [HAMAP]

Taxonomic identifier

331678 [NCBI]

Taxonomic lineage

Bacteria › Chlorobi › Chlorobia › Chlorobiales › Chlorobiaceae › Chlorobium/Pelodictyon group › Chlorobium

Protein attributes

Sequence length	383 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. SAAS SAAS003835
Catalytic activity	UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate = UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate. SAAS SAAS003835
Pathway	Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 5/6. SAAS SAAS003835

Ontologies

Keywords
Biological process	Lipid A biosynthesis SAAS SAAS003835 Lipid synthesis
Molecular function	Glycosyltransferase SAAS SAAS003835 EMBL ACE03412.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	lipid-A-disaccharide synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B3EM34 [UniParc]. Last modified July 22, 2008. Version 1. Checksum: EC7170452FA89C8B	FASTA	383	42,940
	10 20 30 40 50 60 MREKKLFVLA GEVSGDLHAS EVIEVVQTRC PAIRVFGAGG RKLRDLGADL LYDVDDLSVM 70 80 90 100 110 120 GFFEVAGKGF FLRKVIRDLK RAIAARKPDA ALLVDYPGMN MVLARYLHQH DIPVIYYISP 130 140 150 160 170 180 KVWAWKESRI AKIKAYVDRL MVIFDFEVDF YKMHGVEAEF AGNPVVEEIS RLEFRSKSDF 190 200 210 220 230 240 LSDHRIQENR KIIGLLPGSR KQEIALVFPE MLRAAGMLQQ QYDAAFLLGR APHVNHRLYD 250 260 270 280 290 300 SIAGRAGVEL VDCSAYEAMH YSDLVLVTSG TATLEALCFG VPMIVLYKTG WLNYAIGKRL 310 320 330 340 350 360 VRLHSFSLAN LVAKGLDEKS QVVTELLQSA VTADRIYEES TVLLDDRDVS EVMRQNLLCA 370 380 REKLGTVRPS ETVASAVCSY LNG

References

[1]

"Complete sequence of Chlorobium phaeobacteroides BS1." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Li T., Liu Z., Zhao F. , Overmann J., Bryant D.A., Richardson P. Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: BS1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001101 Genomic DNA. Translation: ACE03412.1.
RefSeq	YP_001958893.1. NC_010831.1.
3D structure databases
ProteinModelPortal	B3EM34.
ModBase	Search...
Protein-protein interaction databases
STRING	B3EM34.
Protein family/group databases
CAZy	GT19. Glycosyltransferase Family 19.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6374112.
GenomeReviews	Gene locus Cphamn1_0448 in contig CP001101_GR.
KEGG	cpb:Cphamn1_0448.
PATRIC	21382962. VBIChlPha121022_0491.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG584837.
OMA	PDFNLGL.
ProtClustDB	CLSK637261.
Family and domain databases
InterPro	IPR003835. Glyco_trans_19. [Graphical view]
KO	K00748.
Pfam	PF02684. LpxB. 1 hit. [Graphical view]
TIGRFAMs	TIGR00215. LpxB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B3EM34_CHLPB

Accession

Primary (citable) accession number: B3EM34

Entry history

Integrated into UniProtKB/TrEMBL:	July 22, 2008
Last sequence update:	July 22, 2008
Last modified:	December 14, 2011
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)