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B3ELF6 (B3ELF6_CHLPB) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
1-deoxy-D-xylulose-5-phosphate synthase HAMAP MF_00315
EC=2.2.1.7 HAMAP MF_00315
Alternative name(s):
1-deoxyxylulose-5-phosphate synthase HAMAP MF_00315
Gene names
Name:dxs HAMAP MF_00315
Ordered Locus Names:Cphamn1_1826
OrganismChlorobium phaeobacteroides (strain BS1) [Complete proteome] [HAMAP]
Taxonomic identifier331678 [NCBI]
Taxonomic lineageBacteria › Chlorobi › Chlorobia › Chlorobiales › Chlorobiaceae › Chlorobium/Pelodictyon group › Chlorobium

Protein attributes

Sequence length659 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) By similarity. HAMAP MF_00315 SAAS SAAS001017

Catalytic activity

Pyruvate + D-glyceraldehyde 3-phosphate = 1-deoxy-D-xylulose 5-phosphate + CO2. HAMAP MF_00315 SAAS SAAS001017

Cofactor

Binds 1 thiamine pyrophosphate per subunit By similarity. HAMAP MF_00315 SAAS SAAS001017

Pathway

Metabolic intermediate biosynthesis; 1-deoxy-D-xylulose 5-phosphate biosynthesis; 1-deoxy-D-xylulose 5-phosphate from D-glyceraldehyde 3-phosphate and pyruvate: step 1/1. HAMAP MF_00315 SAAS SAAS001017

Subunit structure

Homodimer By similarity. HAMAP MF_00315 SAAS SAAS001017

Sequence similarities

Belongs to the transketolase family. DXPS subfamily. HAMAP MF_00315

Sequences

Sequence LengthMass (Da)Tools
B3ELF6 [UniParc].

Last modified July 22, 2008. Version 1.
Checksum: 7CC92D5E8F5A38A2

FASTA65971,863
        10         20         30         40         50         60 
MEQFHPVPPN GKYPFLSAIV SPEDLKKHTI HDLQKIADEC RSYLIDVVAE NGGHFGSSLG 

        70         80         90        100        110        120 
VVEMSVAMHY VYNSPHDKII WDVGHQAYIH KILTGRKELM HTNRKFNGLA GFPKISESAH 

       130        140        150        160        170        180 
DAFGTGHAST SISAAAGIAA AKKLSGSNDK VIAVIGDGSM TGGMAFEAMN HLGDIKSDVL 

       190        200        210        220        230        240 
VVLNDNQMAI SPSTGGLKNY LVNITLNKTY NKARKFIWDS LSLLNNDLGE TAKNAVRKIE 

       250        260        270        280        290        300 
DGIKAALTPG AFFEALGFRY FGPIDGHNTE QLVKAFREMQ ELPHPKLLHI ITTKGKGFKP 

       310        320        330        340        350        360 
AEDDQSKWHA SSGGFDITTG KSLKKSGIAQ PPKYQDIFGA ALAELADSDH RITGITAAMS 

       370        380        390        400        410        420 
SGTSLDIFQK AHPERFYDVG IAEQHAVTFA AGMAANGYKP FCAIYSTFLQ RAYDQLIHDV 

       430        440        450        460        470        480 
ALQKLPVVFA IDRAGLVGED GPTHHGSFDL SFLRPIPGMV IMAPKDGQEL RDMLYTASKY 

       490        500        510        520        530        540 
QNGPAAIRYP RGLSSEITLR PGFREIEIGK GKIVREGSSV AILAIGTMVE RALEASLLLE 

       550        560        570        580        590        600 
ENGIDALVAN MRFLKPLDTA LLDDIAETHT DIVVLEENSI IGGLNSAVND YLRSKRRTNN 

       610        620        630        640        650 
VLSIGLPDAF VTHGSMNDLY RLLELDAENI SRKISAFHQC MVTEKNDSTQ STMRTERLA

« Hide

References

[1]"Complete sequence of Chlorobium phaeobacteroides BS1."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Li T., Liu Z., Zhao F. expand/collapse author list , Overmann J., Bryant D.A., Richardson P.
Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: BS1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001101 Genomic DNA. Translation: ACE04744.1.
RefSeqYP_001960225.1. NC_010831.1.

3D structure databases

ProteinModelPortalB3ELF6.
ModBaseSearch...

Protein-protein interaction databases

STRINGB3ELF6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6375517.
GenomeReviewsGene locus Cphamn1_1826 in contig CP001101_GR.
KEGGcpb:Cphamn1_1826.
PATRIC21386020. VBIChlPha121022_1995.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG571647.
OMAIMEYAYL.
ProtClustDBPRK05444.

Family and domain databases

HAMAPMF_00315. DXP_synth.
[Tree]
InterProIPR001017. DH_E1.
IPR005477. Dxylulose-5-P_synthase.
IPR009014. Transketo_C/Pyr-ferredox_oxred.
IPR015941. Transketolase-like_C.
IPR005475. Transketolase-like_Pyr-bd.
IPR020826. Transketolase_BS.
IPR005476. Transketolase_C.
IPR005474. Transketolase_N.
[Graphical view]
Gene3DG3DSA:3.40.50.920. Transketo_C_like. 1 hit.
KOK01662.
PfamPF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 1 hit.
PF02780. Transketolase_C. 1 hit.
[Graphical view]
SMARTSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMSSF52922. Transketo_C_like. 1 hit.
TIGRFAMsTIGR00204. Dxs. 1 hit.
PROSITEPS00801. TRANSKETOLASE_1. 1 hit.
PS00802. TRANSKETOLASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB3ELF6_CHLPB
AccessionPrimary (citable) accession number: B3ELF6
Entry history
Integrated into UniProtKB/TrEMBL: July 22, 2008
Last sequence update: July 22, 2008
Last modified: December 14, 2011
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info