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B3EKJ7

- GSA_CHLPB

UniProt

B3EKJ7 - GSA_CHLPB

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Protein
Glutamate-1-semialdehyde 2,1-aminomutase
Gene
hemL, Cphamn1_0202
Organism
Chlorobium phaeobacteroides (strain BS1)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

(S)-4-amino-5-oxopentanoate = 5-aminolevulinate.UniRule annotation

Cofactori

Pyridoxal phosphate By similarity.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. glutamate-1-semialdehyde 2,1-aminomutase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: InterPro
  3. transaminase activity Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. chlorophyll biosynthetic process Source: UniProtKB-HAMAP
  2. protoporphyrinogen IX biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Chlorophyll biosynthesis, Porphyrin biosynthesis

Keywords - Ligandi

Pyridoxal phosphate

Enzyme and pathway databases

BioCyciCPHA331678:GHME-215-MONOMER.
UniPathwayiUPA00251; UER00317.
UPA00668.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate-1-semialdehyde 2,1-aminomutase (EC:5.4.3.8)
Short name:
GSA
Alternative name(s):
Glutamate-1-semialdehyde aminotransferase
Short name:
GSA-AT
Gene namesi
Name:hemL
Ordered Locus Names:Cphamn1_0202
OrganismiChlorobium phaeobacteroides (strain BS1)
Taxonomic identifieri331678 [NCBI]
Taxonomic lineageiBacteriaChlorobiChlorobiaChlorobialesChlorobiaceaeChlorobium/Pelodictyon groupChlorobium
ProteomesiUP000001228: Chromosome

Subcellular locationi

Cytoplasm Reviewed prediction UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 431431Glutamate-1-semialdehyde 2,1-aminomutaseUniRule annotation
PRO_1000121866Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei269 – 2691N6-(pyridoxal phosphate)lysine By similarity

Interactioni

Subunit structurei

Homodimer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi331678.Cphamn1_0202.

Structurei

3D structure databases

ProteinModelPortaliB3EKJ7.
SMRiB3EKJ7. Positions 1-421.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0001.
HOGENOMiHOG000020210.
KOiK01845.
OMAiKRLMEPG.
OrthoDBiEOG6QVRHN.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 2 hits.
HAMAPiMF_00375. HemL_aminotrans_3.
InterProiIPR004639. 4pyrrol_synth_GluAld_NH2Trfase.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11986. PTHR11986. 1 hit.
PfamiPF00202. Aminotran_3. 1 hit.
[Graphical view]
PIRSFiPIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR00713. hemL. 1 hit.
PROSITEiPS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B3EKJ7-1 [UniParc]FASTAAdd to Basket

« Hide

MPQLTRSAEL FEKAKQFIPG GVNSPVRAFK SVGGTPIFMA KGQGAYMTDV    50
DGNTYLDYVG SWGPFILGSM HPRITAAIEN TLTKIGTSFG TPIEMEIEIA 100
ELLTQIVPSI EMVRMVNSGT EATMSAVRLA RGYTGRDKII KFEGCYHGHG 150
DSFLIKAGSG ALTLGAPDSP GVTKGTANDT LNAKYNDIES VRVLVKENKD 200
SIAAIIIEPV AGNTGVIPAK TDFLQALRDL CTEEGIVLIF DEVMCGFRVA 250
LGGAQERYGI TPDLTTMGKI IGGGLPVGAF GGKREIMQRV APIGDVYQAG 300
TLSGNPLALT AGLETLKILR DDNPYPELER KAAFLEEGFR DNMNKLGLSY 350
VQNRVGSMAC LFFTETPVEN YDTAITCDLK KYGKYYHSML DQGIYLAPSQ 400
FEAMFTSAVM TDEDLEKTVK ANYVALQAAE A 431
Length:431
Mass (Da):46,503
Last modified:July 22, 2008 - v1
Checksum:i2248A7DC16751E62
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001101 Genomic DNA. Translation: ACE03175.1.
RefSeqiYP_001958656.1. NC_010831.1.

Genome annotation databases

EnsemblBacteriaiACE03175; ACE03175; Cphamn1_0202.
GeneIDi6373857.
KEGGicpb:Cphamn1_0202.
PATRICi21382383. VBIChlPha121022_0211.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001101 Genomic DNA. Translation: ACE03175.1 .
RefSeqi YP_001958656.1. NC_010831.1.

3D structure databases

ProteinModelPortali B3EKJ7.
SMRi B3EKJ7. Positions 1-421.
ModBasei Search...

Protein-protein interaction databases

STRINGi 331678.Cphamn1_0202.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACE03175 ; ACE03175 ; Cphamn1_0202 .
GeneIDi 6373857.
KEGGi cpb:Cphamn1_0202.
PATRICi 21382383. VBIChlPha121022_0211.

Phylogenomic databases

eggNOGi COG0001.
HOGENOMi HOG000020210.
KOi K01845.
OMAi KRLMEPG.
OrthoDBi EOG6QVRHN.

Enzyme and pathway databases

UniPathwayi UPA00251 ; UER00317 .
UPA00668 .
BioCyci CPHA331678:GHME-215-MONOMER.

Family and domain databases

Gene3Di 3.40.640.10. 1 hit.
3.90.1150.10. 2 hits.
HAMAPi MF_00375. HemL_aminotrans_3.
InterProi IPR004639. 4pyrrol_synth_GluAld_NH2Trfase.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view ]
PANTHERi PTHR11986. PTHR11986. 1 hit.
Pfami PF00202. Aminotran_3. 1 hit.
[Graphical view ]
PIRSFi PIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
SUPFAMi SSF53383. SSF53383. 1 hit.
TIGRFAMsi TIGR00713. hemL. 1 hit.
PROSITEi PS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BS1.

Entry informationi

Entry nameiGSA_CHLPB
AccessioniPrimary (citable) accession number: B3EKJ7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: July 22, 2008
Last modified: May 14, 2014
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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