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Protein

Dihydrolipoyl dehydrogenase

Gene

Cphamn1_1481

Organism
Chlorobium phaeobacteroides (strain BS1)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Catalytic activityi

Protein N(6)-(dihydrolipoyl)lysine + NAD+ = protein N(6)-(lipoyl)lysine + NADH.UniRule annotation

Cofactori

FADUniRule annotationNote: Binds 1 FAD per subunit.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Keywords - Ligandi

FADUniRule annotation, Flavoprotein, NADUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Dihydrolipoyl dehydrogenaseUniRule annotation (EC:1.8.1.4UniRule annotation)
Gene namesi
Ordered Locus Names:Cphamn1_1481Imported
OrganismiChlorobium phaeobacteroides (strain BS1)Imported
Taxonomic identifieri331678 [NCBI]
Taxonomic lineageiBacteriaChlorobiChlorobiaChlorobialesChlorobiaceaeChlorobium/Pelodictyon groupChlorobium
Proteomesi
  • UP000001228 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi331678.Cphamn1_1481.

Structurei

3D structure databases

ProteinModelPortaliB3EJN8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 329FAD/NAD-binding_domInterPro annotationAdd BLAST325
Domaini349 – 451Pyr_redox_dimInterPro annotationAdd BLAST103

Keywords - Domaini

Redox-active centerUniRule annotation

Phylogenomic databases

eggNOGiENOG4107QQC. Bacteria.
COG1249. LUCA.
HOGENOMiHOG000276709.
OMAiPYQFTHM.
OrthoDBiPOG091H0239.

Family and domain databases

Gene3Di3.30.390.30. 1 hit.
3.50.50.60. 2 hits.
InterProiIPR023753. FAD/NAD-binding_dom.
IPR016156. FAD/NAD-linked_Rdtase_dimer.
IPR006258. Lipoamide_DH.
IPR004099. Pyr_nucl-diS_OxRdtase_dimer.
[Graphical view]
PfamiPF07992. Pyr_redox_2. 1 hit.
PF02852. Pyr_redox_dim. 1 hit.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 1 hit.
SSF55424. SSF55424. 1 hit.
TIGRFAMsiTIGR01350. lipoamide_DH. 1 hit.

Sequencei

Sequence statusi: Complete.

B3EJN8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNFDFDVIVI GGGAAGLTAA GVSASLGAKT AMIEKKKLGG DCTWYGCIPS
60 70 80 90 100
KALLKSAKVA QTVREAEKFG IKTGNLSIDF EAVMKRVRSI QQDVYQEADA
110 120 130 140 150
PEIYEAMGVT VIEGRGSFAD EHSVIITKEG MDDLTLRSKN IVIATGSRPV
160 170 180 190 200
IPPIEGLETV PFLTNETIFT LEKQPKKLLV IGAGPIGTEM GQAFTRLGSE
210 220 230 240 250
VTVFDFGERI LSHDHPELSA LLHDMLTREG INFRLNTAVK KVAKKNNSIV
260 270 280 290 300
VTAEDRNTGE SFSVEGDALL VASGRKAAIE TLNLEAAGID THKRGIRVNE
310 320 330 340 350
SCQTSRHHIY ACGDVAGGLQ FTHMAEHMAK VAASKMLTHL PMKTDDKHVP
360 370 380 390 400
WCTYTEPELA HVGETEETLK KNNTGYELYR FPFNRIDRAI TESEKQGWIR
410 420 430 440 450
VYAAGFDGRI FGVDILGVHA GELISEFALA MRNGVTLRQM SDTIHPYPTY
460 470 480 490
ALGNRRAADQ WYVRKQSGAL VGLLQFFFGY QGKMPDTSDP DRIV
Length:494
Mass (Da):54,116
Last modified:July 22, 2008 - v1
Checksum:i9A336A9C6C5B566D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001101 Genomic DNA. Translation: ACE04407.1.
RefSeqiWP_012474888.1. NC_010831.1.

Genome annotation databases

EnsemblBacteriaiACE04407; ACE04407; Cphamn1_1481.
KEGGicpb:Cphamn1_1481.
PATRICi21385218. VBIChlPha121022_1606.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001101 Genomic DNA. Translation: ACE04407.1.
RefSeqiWP_012474888.1. NC_010831.1.

3D structure databases

ProteinModelPortaliB3EJN8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi331678.Cphamn1_1481.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACE04407; ACE04407; Cphamn1_1481.
KEGGicpb:Cphamn1_1481.
PATRICi21385218. VBIChlPha121022_1606.

Phylogenomic databases

eggNOGiENOG4107QQC. Bacteria.
COG1249. LUCA.
HOGENOMiHOG000276709.
OMAiPYQFTHM.
OrthoDBiPOG091H0239.

Family and domain databases

Gene3Di3.30.390.30. 1 hit.
3.50.50.60. 2 hits.
InterProiIPR023753. FAD/NAD-binding_dom.
IPR016156. FAD/NAD-linked_Rdtase_dimer.
IPR006258. Lipoamide_DH.
IPR004099. Pyr_nucl-diS_OxRdtase_dimer.
[Graphical view]
PfamiPF07992. Pyr_redox_2. 1 hit.
PF02852. Pyr_redox_dim. 1 hit.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 1 hit.
SSF55424. SSF55424. 1 hit.
TIGRFAMsiTIGR01350. lipoamide_DH. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiB3EJN8_CHLPB
AccessioniPrimary (citable) accession number: B3EJN8
Entry historyi
Integrated into UniProtKB/TrEMBL: July 22, 2008
Last sequence update: July 22, 2008
Last modified: November 2, 2016
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Miscellaneous

The active site is a redox-active disulfide bond.UniRule annotation

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.