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B3EH05

- SYL_CHLL2

UniProt

B3EH05 - SYL_CHLL2

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Protein

Leucine--tRNA ligase

Gene

leuS

Organism
Chlorobium limicola (strain DSM 245 / NBRC 103803)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu).UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei579 – 5791ATPUniRule annotation

GO - Molecular functioni

  1. aminoacyl-tRNA editing activity Source: InterPro
  2. ATP binding Source: UniProtKB-HAMAP
  3. leucine-tRNA ligase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. leucyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCLIM290315:GHUH-626-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Leucine--tRNA ligaseUniRule annotation (EC:6.1.1.4UniRule annotation)
Alternative name(s):
Leucyl-tRNA synthetaseUniRule annotation
Short name:
LeuRSUniRule annotation
Gene namesi
Name:leuSUniRule annotation
Ordered Locus Names:Clim_0598
OrganismiChlorobium limicola (strain DSM 245 / NBRC 103803)
Taxonomic identifieri290315 [NCBI]
Taxonomic lineageiBacteriaChlorobiChlorobiaChlorobialesChlorobiaceaeChlorobium/Pelodictyon groupChlorobium
ProteomesiUP000008841: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 805805Leucine--tRNA ligasePRO_1000091302Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi290315.Clim_0598.

Structurei

3D structure databases

ProteinModelPortaliB3EH05.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi40 – 5112"HIGH" regionAdd
BLAST
Motifi576 – 5805"KMSKS" region

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0495.
HOGENOMiHOG000200748.
KOiK01869.
OMAiERYWMNV.
OrthoDBiEOG63Z74X.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.40.50.620. 2 hits.
3.90.740.10. 1 hit.
HAMAPiMF_00049_B. Leu_tRNA_synth_B.
InterProiIPR002300. aa-tRNA-synth_Ia.
IPR002302. Leu-tRNA-ligase.
IPR025709. Leu_tRNA-synth_edit.
IPR015413. Methionyl/Leucyl_tRNA_Synth.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
IPR013155. V/L/I-tRNA-synth_anticodon-bd.
IPR009008. Val/Leu/Ile-tRNA-synth_edit.
[Graphical view]
PANTHERiPTHR11946:SF7. PTHR11946:SF7. 1 hit.
PfamiPF08264. Anticodon_1. 1 hit.
PF00133. tRNA-synt_1. 1 hit.
PF13603. tRNA-synt_1_2. 1 hit.
PF09334. tRNA-synt_1g. 1 hit.
[Graphical view]
PRINTSiPR00985. TRNASYNTHLEU.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF50677. SSF50677. 1 hit.
TIGRFAMsiTIGR00396. leuS_bact. 1 hit.

Sequencei

Sequence statusi: Complete.

B3EH05-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRYEFSAIEK KWQAIWQENG TFKTGESTEK PKYYVLDMFP YPSGSGLHVG
60 70 80 90 100
HLEGYTASDI IARFKRSRGF NVLHPMGWDA FGLPAEQYAI KTGTHPKITT
110 120 130 140 150
ENNIRSFRET LQAMGFSYDW SKEINTTDPA YFKWTQWIFL RLYEMGLAYM
160 170 180 190 200
SDVDVNWCEE LKTVLANEEV DEKIADGYTV VRKPLRQWVL KITAYAERLL
210 220 230 240 250
ADLDELEWPE NVKQMQRNWI GRSEGVEIDF ELRCHGKNLR VYTTRPDTLF
260 270 280 290 300
GATYLVVSPE HPLAEKLATA DNLKEVKAYI SRAKLKTELE RTGLQKDKTG
310 320 330 340 350
VFTGSYAINP ATGNPLPVWI SDFVLISYGT GAIMSVPAHD SRDWEFAKKF
360 370 380 390 400
DLPIIEVIKS PHDVNDAVFE GKESVPVNSS NSEITIDGLP FREAFDTMAS
410 420 430 440 450
WLEKKGAGKR TINYKLRDWI FSRQRYWGEP IPIKHYEDGT LRTETILPLT
460 470 480 490 500
LPDVEAYQPS ETGESPLATI HDWLYGSDEF GSFRRETNTM PQWAGSCWYY
510 520 530 540 550
LRFIDPENSG RLIDPEREKY WMNVDLYIGG AEHAVLHLLY ARFWHKVLFD
560 570 580 590 600
LNVVSTVEPF RKLFNQGMIL GEDNEKMSKS RGNVIPADHV LKTYGADAVR
610 620 630 640 650
LYEMFLGPLE QVKPWNTNGI EGISRFLGKV WRLVYPEQEG NKAELTDETM
660 670 680 690 700
PEELLRRLHK TIRKVTEDTE ALKFNTAIAE MMVLVNELQR NGCRNRTAVE
710 720 730 740 750
SMILLLAPYA PHIAEELWQA TGHTGSISNE PFPNYVAGLA TDSVVQIAVQ
760 770 780 790 800
VNGKLRGTFS TPAGTPQNSL IETARNVESV MKFLEGKAIM REIVVPDKLV

NFAVK
Length:805
Mass (Da):91,997
Last modified:July 22, 2008 - v1
Checksum:iD4F3FE28F9E92DF3
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001097 Genomic DNA. Translation: ACD89685.1.
RefSeqiYP_001942664.1. NC_010803.1.

Genome annotation databases

EnsemblBacteriaiACD89685; ACD89685; Clim_0598.
GeneIDi6354046.
KEGGicli:Clim_0598.
PATRICi21373191. VBIChlLim118737_0638.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001097 Genomic DNA. Translation: ACD89685.1 .
RefSeqi YP_001942664.1. NC_010803.1.

3D structure databases

ProteinModelPortali B3EH05.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 290315.Clim_0598.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACD89685 ; ACD89685 ; Clim_0598 .
GeneIDi 6354046.
KEGGi cli:Clim_0598.
PATRICi 21373191. VBIChlLim118737_0638.

Phylogenomic databases

eggNOGi COG0495.
HOGENOMi HOG000200748.
KOi K01869.
OMAi ERYWMNV.
OrthoDBi EOG63Z74X.

Enzyme and pathway databases

BioCyci CLIM290315:GHUH-626-MONOMER.

Family and domain databases

Gene3Di 1.10.730.10. 1 hit.
3.40.50.620. 2 hits.
3.90.740.10. 1 hit.
HAMAPi MF_00049_B. Leu_tRNA_synth_B.
InterProi IPR002300. aa-tRNA-synth_Ia.
IPR002302. Leu-tRNA-ligase.
IPR025709. Leu_tRNA-synth_edit.
IPR015413. Methionyl/Leucyl_tRNA_Synth.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
IPR013155. V/L/I-tRNA-synth_anticodon-bd.
IPR009008. Val/Leu/Ile-tRNA-synth_edit.
[Graphical view ]
PANTHERi PTHR11946:SF7. PTHR11946:SF7. 1 hit.
Pfami PF08264. Anticodon_1. 1 hit.
PF00133. tRNA-synt_1. 1 hit.
PF13603. tRNA-synt_1_2. 1 hit.
PF09334. tRNA-synt_1g. 1 hit.
[Graphical view ]
PRINTSi PR00985. TRNASYNTHLEU.
SUPFAMi SSF47323. SSF47323. 1 hit.
SSF50677. SSF50677. 1 hit.
TIGRFAMsi TIGR00396. leuS_bact. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 245 / NBRC 103803.

Entry informationi

Entry nameiSYL_CHLL2
AccessioniPrimary (citable) accession number: B3EH05
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: July 22, 2008
Last modified: October 29, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3