Skip Header

Contribute Send feedback
Read comments (?) or add your own

B3EH04 (B3EH04_CHLL2) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 24. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Acetyl-coenzyme A synthetase HAMAP MF_01123
EC=6.2.1.1 HAMAP MF_01123
Alternative name(s):
Acetate--CoA ligase HAMAP MF_01123
Acyl-activating enzyme HAMAP MF_01123
Gene names
Name:acsA HAMAP MF_01123
Ordered Locus Names:Clim_0597
OrganismChlorobium limicola (strain DSM 245 / NBRC 103803) [Complete proteome] [HAMAP]
Taxonomic identifier290315 [NCBI]
Taxonomic lineageBacteria › Chlorobi › Chlorobia › Chlorobiales › Chlorobiaceae › Chlorobium/Pelodictyon group › Chlorobium

Protein attributes

Sequence length657 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA. HAMAP MF_01123

Post-translational modification

Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme By similarity. HAMAP MF_01123

Sequence similarities

Belongs to the ATP-dependent AMP-binding enzyme family. HAMAP MF_01123

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site5291 By similarity HAMAP MF_01123

Amino acid modifications

Modified residue6211N6-acetyllysine By similarity HAMAP MF_01123

Sequences

Sequence LengthMass (Da)Tools
B3EH04 [UniParc].

Last modified July 22, 2008. Version 1.
Checksum: D8B9E965976F3B30

FASTA65773,766
        10         20         30         40         50         60 
MATEENASTN QQSISSVLSE KRKFPPPEQF SQSAHISSME EYEKLYAAAA EDPEAYWGGI 

        70         80         90        100        110        120 
AEQFHWFKKW DSILEWNTPY AKWFNGGKTN ICYNAVDVHM QSWRKNKAAI IWEGEEGNQQ 

       130        140        150        160        170        180 
VITYGELHRQ VSKFANVLKI AGIQPGDRVA IYMGMVPELV IAVLACARVG AVHNVIFAGF 

       190        200        210        220        230        240 
SAHAITERVN DSRAKLVICC DGTRRRGSSI NLKKIVDEAI VNTPSVRSVI VLKVTGETVS 

       250        260        270        280        290        300 
MHDGMDHWWH DLMGLAMDVC EPVHVESEHP LFVLYTSGST GKPKGILHTT AGYMVHAASS 

       310        320        330        340        350        360 
FRYVFDIKDE DIYWCTADVG WITGHSYMVY GPLLNGATLL MYEGAPNYPQ WDRFWDIINR 

       370        380        390        400        410        420 
HKVTILYTAP TAIRAFIRAG NEWVTKHDIS SLRLLGTVGE PINPEAWMWY HKIVGQEKCP 

       430        440        450        460        470        480 
IVDTWWQTET GGIMVSPLPG ATPTKPGTAT RPLPGIMVDV VRKDGTPCEA NEGGYLVIKK 

       490        500        510        520        530        540 
PWPSMLRTIY GDNERYEKTY WSEFDDMYFT GDGARKDEDG YIWIMGRVDD VVNVSGHRLG 

       550        560        570        580        590        600 
TSEVESALVS HEAVAEAAVV SRPDDIKGNA LVAFVTLKDE YEGDMKLRES LRNHVAKEIG 

       610        620        630        640        650 
PIAKPDEIRW AKGLPKTRSG KIMRRLLREL ATSNEIKGDI TTLEDFGVLE NLRDQED

« Hide

References

[1]"Complete sequence of Chlorobium limicola DSM 245."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Zhao F., Li T., Liu Z. expand/collapse author list , Overmann J., Bryant D.A., Richardson P.
Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 245 / NBRC 103803.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001097 Genomic DNA. Translation: ACD89684.1.
RefSeqYP_001942663.1. NC_010803.1.

3D structure databases

ProteinModelPortalB3EH04.
SMRB3EH04. Positions 23-656.
ModBaseSearch...

Protein-protein interaction databases

STRINGB3EH04.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6354045.
GenomeReviewsGene locus Clim_0597 in contig CP001097_GR.
KEGGcli:Clim_0597.
PATRIC21373189. VBIChlLim118737_0637.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG547964.
OMAVISVSGH.
ProtClustDBPRK00174.

Family and domain databases

HAMAPMF_01123. Ac_CoA_synth.
[Tree]
InterProIPR011904. Ac_CoA_lig.
IPR024597. Acyl-CoA_synth_DUF3448.
IPR020845. AMP-binding_CS.
IPR000873. AMP-dep_Synth/Lig.
[Graphical view]
KOK01895.
PANTHERPTHR24095:SF42. PTHR24095:SF42. 1 hit.
PfamPF00501. AMP-binding. 1 hit.
PF11930. DUF3448. 1 hit.
[Graphical view]
TIGRFAMsTIGR02188. Ac_CoA_lig_AcsA. 1 hit.
PROSITEPS00455. AMP_BINDING. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB3EH04_CHLL2
AccessionPrimary (citable) accession number: B3EH04
Entry history
Integrated into UniProtKB/TrEMBL: July 22, 2008
Last sequence update: July 22, 2008
Last modified: December 14, 2011
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info