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B3EGU6 (B3EGU6_CHLL2) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase HAMAP MF_00387
Short name=UDP-N-acetylglucosamine acyltransferase HAMAP MF_00387
EC=2.3.1.129 HAMAP MF_00387
Gene names
Name:lpxA HAMAP MF_00387
Ordered Locus Names:Clim_2185
OrganismChlorobium limicola (strain DSM 245 / NBRC 103803) [Complete proteome] [HAMAP]
Taxonomic identifier290315 [NCBI]
Taxonomic lineageBacteria › Chlorobi › Chlorobia › Chlorobiales › Chlorobiaceae › Chlorobium/Pelodictyon group › Chlorobium

Protein attributes

Sequence length265 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. HAMAP MF_00387 SAAS SAAS010137

Catalytic activity

(R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] + UDP-N-acetylglucosamine = [acyl-carrier-protein] + UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine. HAMAP MF_00387 SAAS SAAS010137

Pathway

Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 1/6. HAMAP MF_00387 SAAS SAAS010137

Subunit structure

Homotrimer By similarity. HAMAP MF_00387 SAAS SAAS010137

Subcellular location

Cytoplasm By similarity HAMAP MF_00387 SAAS SAAS010137.

Sequence similarities

Belongs to the transferase hexapeptide repeat family. LpxA subfamily. HAMAP MF_00387

Sequences

Sequence LengthMass (Da)Tools
B3EGU6 [UniParc].

Last modified July 22, 2008. Version 1.
Checksum: 686F1DCB4401444B

FASTA26528,372
        10         20         30         40         50         60 
MSSRIHATAI ISPEAFLSAG VSVGPYSVIE EDVTIGEGTV VGPQVHIASG TRIGNNCRIH 

        70         80         90        100        110        120 
TGAVLAGEPQ DLKFAGEKTY LYIGDRTVIR ECVTLNRGTK ASGKTVVGSD NLIMAYVHAG 

       130        140        150        160        170        180 
HDCVIGNHVV IANSVQFGGH CEVGDYAVIG GLTGVHQFVR IGRYTMVGGI ARASLDVPPF 

       190        200        210        220        230        240 
VMAGGHSTFR YEGLNAIGLK RRGFSPESIS RIRDVYRIVF QSGLLLSNAL EKVEAEFAPE 

       250        260 
PEILEILGFF KSGTHGRKFI RPFNS

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References

[1]"Complete sequence of Chlorobium limicola DSM 245."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Zhao F., Li T., Liu Z. expand/collapse author list , Overmann J., Bryant D.A., Richardson P.
Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 245 / NBRC 103803.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001097 Genomic DNA. Translation: ACD91209.1.
RefSeqYP_001944188.1. NC_010803.1.

3D structure databases

ProteinModelPortalB3EGU6.
ModBaseSearch...

Protein-protein interaction databases

STRINGB3EGU6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6355979.
GenomeReviewsGene locus Clim_2185 in contig CP001097_GR.
KEGGcli:Clim_2185.
PATRIC21376671. VBIChlLim118737_2355.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG659295.
OMAREFCTFN.
ProtClustDBPRK05289.

Family and domain databases

HAMAPMF_00387. LpxA.
[Tree]
InterProIPR001451. Hexapep_transf.
IPR010137. Lipid_A_lpxA.
IPR011004. Trimer_LpxA-like.
[Graphical view]
KOK00677.
PfamPF00132. Hexapep. 3 hits.
[Graphical view]
PIRSFPIRSF000456. UDP-GlcNAc_acltr. 1 hit.
SUPFAMSSF51161. Trimer_LpxA_like. 1 hit.
TIGRFAMsTIGR01852. Lipid_A_lpxA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB3EGU6_CHLL2
AccessionPrimary (citable) accession number: B3EGU6
Entry history
Integrated into UniProtKB/TrEMBL: July 22, 2008
Last sequence update: July 22, 2008
Last modified: December 14, 2011
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info