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B3EGN4 (AROA_CHLL2) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-phosphoshikimate 1-carboxyvinyltransferase
EC=2.5.1.19
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate synthase
Short name=EPSP synthase
Short name=EPSPS
Gene names
Name:aroA
Ordered Locus Names:Clim_2123
OrganismChlorobium limicola (strain DSM 245 / NBRC 103803) [Complete proteome] [HAMAP]
Taxonomic identifier290315 [NCBI]
Taxonomic lineageBacteria › Chlorobi › Chlorobia › Chlorobiales › Chlorobiaceae › Chlorobium/Pelodictyon group › Chlorobium

Protein attributes

Sequence length434 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. HAMAP MF_00210

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7. HAMAP MF_00210

Subunit structure

Monomer By similarity. HAMAP MF_00210

Subcellular location

Cytoplasm By similarity HAMAP MF_00210.

Sequence similarities

Belongs to the EPSP synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   Molecular functionTransferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-phosphoshikimate 1-carboxyvinyltransferase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 4344343-phosphoshikimate 1-carboxyvinyltransferase HAMAP MF_00210
PRO_1000099678

Sequences

Sequence LengthMass (Da)Tools
B3EGN4 [UniParc].

Last modified July 22, 2008. Version 1.
Checksum: 8169590144939952

FASTA43446,867
        10         20         30         40         50         60 
MAVFKGEVTA LPPDKSISHR AALIGSLSEG VTEITNFSAG FDNQSTLGVL HDAGIEVSQH 

        70         80         90        100        110        120 
EIDGAYGRRI RKVIISSRGL WSFTAPEKPL MCNNSGSTMR MFAGILAAQP FESELVGDSS 

       130        140        150        160        170        180 
LMKRPMKRVA DPLRQMGAGV DLSPAGTAPV RIRGTRDLTP LEYRLPVPSA QVKSLVTFAA 

       190        200        210        220        230        240 
LHADGETRII ESIRSRNHTE LMLGLETIDR PDGERVIVIP GRKTIVARSF YIPADPSAAC 

       250        260        270        280        290        300 
FIVALGLLGS NSEIIIRDVC LNPTRVEFIP LLTGAGADIT IENSRIIGGE TIGDILVRST 

       310        320        330        340        350        360 
RTLKPLVISN PTVVAGVIDE LPMLSVLSAF SSGEFELHNA EELRTKESDR INAIVVNLER 

       370        380        390        400        410        420 
LGFDCEQYPD GFRVIGRRCR PVGQVTVACF DDHRIAMSFA VAARATGEGI ALSDSDVVGV 

       430 
SFPNFFEIIE NLKA

« Hide

References

[1]"Complete sequence of Chlorobium limicola DSM 245."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Zhao F., Li T., Liu Z. expand/collapse author list , Overmann J., Bryant D.A., Richardson P.
Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 245 / NBRC 103803.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001097 Genomic DNA. Translation: ACD91147.1.
RefSeqYP_001944126.1. NC_010803.1.

3D structure databases

ProteinModelPortalB3EGN4.
ModBaseSearch...

Protein-protein interaction databases

STRINGB3EGN4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6355101.
GenomeReviewsGene locus Clim_2123 in contig CP001097_GR.
KEGGcli:Clim_2123.
PATRIC21376539. VBIChlLim118737_2289.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG646626.
OMALECANIS.
ProtClustDBPRK02427.

Family and domain databases

HAMAPMF_00210. EPSP_synth.
[Tree]
InterProIPR001986. Enolpyruvate_Tfrase_dom.
IPR006264. EPSP_synthase.
IPR023193. EPSP_synthase_CS.
IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
[Graphical view]
Gene3DG3DSA:3.65.10.10. EPSP_synthase. 2 hits.
KOK00800.
PfamPF00275. EPSP_synthase. 1 hit.
[Graphical view]
PIRSFPIRSF000505. EPSPS. 1 hit.
SUPFAMSSF55205. RNA3'_cycl/enolpyr_transf_A/B. 1 hit.
TIGRFAMsTIGR01356. AroA. 1 hit.
PROSITEPS00104. EPSP_SYNTHASE_1. False negative.
PS00885. EPSP_SYNTHASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROA_CHLL2
AccessionPrimary (citable) accession number: B3EGN4
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: July 22, 2008
Last modified: January 25, 2012
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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