B3EFF2 (B3EFF2_CHLL2) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Lipid-A-disaccharide synthase EMBL ACD89435.1
EC=2.4.1.182 EMBL ACD89435.1

Gene names

Ordered Locus Names:

Clim_0342

Organism

Chlorobium limicola (strain DSM 245 / NBRC 103803) [Complete proteome] [HAMAP]

Taxonomic identifier

290315 [NCBI]

Taxonomic lineage

Bacteria › Chlorobi › Chlorobia › Chlorobiales › Chlorobiaceae › Chlorobium/Pelodictyon group › Chlorobium

Protein attributes

Sequence length	380 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. SAAS SAAS003835
Catalytic activity	UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate = UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate. SAAS SAAS003835
Pathway	Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 5/6. SAAS SAAS003835

Ontologies

Keywords
Biological process	Lipid A biosynthesis SAAS SAAS003835 Lipid synthesis
Molecular function	Glycosyltransferase SAAS SAAS003835 EMBL ACD89435.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	lipid-A-disaccharide synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B3EFF2 [UniParc]. Last modified July 22, 2008. Version 1. Checksum: 2ACEA6245B1D8DC7	FASTA	380	42,379
	10 20 30 40 50 60 MSRTLFVLAG EVSGDMHAAG VVAELLRRKP DVRVFGIGGE RLRALGAELS FDTRQMSIMG 70 80 90 100 110 120 FVDVLRHAGF LRKVISELKR LVRAEKPDAA LLVDYPGMNL IMARFLHDLG IPVIFYISPQ 130 140 150 160 170 180 VWAWKEGRVG KIRKTVDRLL VIFDFEVDFY RRRGVNAEFV GNPVIEELRD EELPPADVFL 190 200 210 220 230 240 RKHHIEQGAI LIGLLPGSRR QEISKILPEM IRAAGMLGEQ YNAVFLLGRA PHLDFRWQDH 250 260 270 280 290 300 VAEDRDIRVV ECRSYEVMKY SNLAFVTSGT ATLEALCFGL PMIVVYRTGW MNYQIGKRLV 310 320 330 340 350 360 KLKSISLANI VARGLGAAGQ AVPELIQHDA CAEGMVKAAM QLLDNPALAA DMRAELLGAR 370 380 DKLASASPSR AVTAIIEEYL

References

[1]

"Complete sequence of Chlorobium limicola DSM 245." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Zhao F., Li T., Liu Z. , Overmann J., Bryant D.A., Richardson P. Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 245 / NBRC 103803.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001097 Genomic DNA. Translation: ACD89435.1.
RefSeq	YP_001942414.1. NC_010803.1.
3D structure databases
ProteinModelPortal	B3EFF2.
ModBase	Search...
Protein-protein interaction databases
STRING	B3EFF2.
Protein family/group databases
CAZy	GT19. Glycosyltransferase Family 19.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6354336.
GenomeReviews	Gene locus Clim_0342 in contig CP001097_GR.
KEGG	cli:Clim_0342.
PATRIC	21372635. VBIChlLim118737_0367.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG584837.
OMA	PDFNLGL.
ProtClustDB	CLSK637261.
Family and domain databases
InterPro	IPR003835. Glyco_trans_19. [Graphical view]
KO	K00748.
Pfam	PF02684. LpxB. 1 hit. [Graphical view]
TIGRFAMs	TIGR00215. LpxB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B3EFF2_CHLL2

Accession

Primary (citable) accession number: B3EFF2

Entry history

Integrated into UniProtKB/TrEMBL:	July 22, 2008
Last sequence update:	July 22, 2008
Last modified:	December 14, 2011
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)