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B3EEG5 (B3EEG5_CHLL2) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Non-canonical purine NTP pyrophosphatase HAMAP MF_01405
EC=3.6.1.19 HAMAP MF_01405
Alternative name(s):
Non-standard purine NTP pyrophosphatase HAMAP MF_01405
Nucleoside-triphosphate diphosphatase HAMAP MF_01405
Nucleoside-triphosphate pyrophosphatase HAMAP MF_01405
Gene names
Ordered Locus Names:Clim_1734
OrganismChlorobium limicola (strain DSM 245 / NBRC 103803) [Complete proteome] [HAMAP]
Taxonomic identifier290315 [NCBI]
Taxonomic lineageBacteria › Chlorobi › Chlorobia › Chlorobiales › Chlorobiaceae › Chlorobium/Pelodictyon group › Chlorobium

Protein attributes

Sequence length230 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP/dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions By similarity. HAMAP MF_01405

Catalytic activity

A nucleoside triphosphate + H2O = a nucleotide + diphosphate. HAMAP MF_01405 SAAS SAAS020922

Cofactor

Binds 1 divalent metal cation ion per subunit; can use either magnesium or manganese By similarity. HAMAP MF_01405 SAAS SAAS020922

Subunit structure

Homodimer By similarity. HAMAP MF_01405 SAAS SAAS020922

Sequence similarities

Belongs to the HAM1 NTPase family. HAMAP MF_01405 RuleBase RU003781

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region18 – 236Substrate binding By similarity HAMAP MF_01405
Region87 – 882Substrate binding By similarity HAMAP MF_01405

Sites

Metal binding531Magnesium or manganese By similarity HAMAP MF_01405
Metal binding871Magnesium or manganese By similarity HAMAP MF_01405
Binding site1821Substrate By similarity HAMAP MF_01405
Binding site2021Substrate By similarity HAMAP MF_01405
Binding site2081Substrate By similarity HAMAP MF_01405

Sequences

Sequence LengthMass (Da)Tools
B3EEG5 [UniParc].

Last modified July 22, 2008. Version 1.
Checksum: 807A893A9E3EB0D4

FASTA23025,095
        10         20         30         40         50         60 
MNGNSICTEK TIPVILATGN PDKVKELRPM LEHISPLFSV FSLSDLDIAA DIEETEQTLS 

        70         80         90        100        110        120 
GNALLKADGI FAILEQRFPF LVTIADDTGL EVLSLGGEPG VLSARFAPVK TGMKPTYEDN 

       130        140        150        160        170        180 
IDHLLLRMNG IKERNARFRT VIALKGRIPS GETAYAFRLT AEGVVEGSIV EERKGIMGFG 

       190        200        210        220        230 
YDPVFHVTSA GKTYAEMAAE EKNTISHRAI ALQKASNALS DIMKKHYTPQ

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References

[1]"Complete sequence of Chlorobium limicola DSM 245."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Zhao F., Li T., Liu Z. expand/collapse author list , Overmann J., Bryant D.A., Richardson P.
Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 245 / NBRC 103803.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001097 Genomic DNA. Translation: ACD90775.1.
RefSeqYP_001943754.1. NC_010803.1.

3D structure databases

ProteinModelPortalB3EEG5.
ModBaseSearch...

Protein-protein interaction databases

STRINGB3EEG5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6354562.
GenomeReviewsGene locus Clim_1734 in contig CP001097_GR.
KEGGcli:Clim_1734.
PATRIC21375673. VBIChlLim118737_1860.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG697237.
OMAYSKRYDQ.
ProtClustDBPRK14826.

Family and domain databases

HAMAPMF_01405. Non_canon_purine_NTPase.
[Tree]
InterProIPR002637. Ham1p-like.
IPR020922. Nucleoside-triphosphatase.
[Graphical view]
KOK02428.
PANTHERPTHR11067. Ham1p_like. 1 hit.
PfamPF01725. Ham1p_like. 1 hit.
[Graphical view]
TIGRFAMsTIGR00042. TIGR00042. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB3EEG5_CHLL2
AccessionPrimary (citable) accession number: B3EEG5
Entry history
Integrated into UniProtKB/TrEMBL: July 22, 2008
Last sequence update: July 22, 2008
Last modified: December 14, 2011
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info