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B3EEG0 (B3EEG0_CHLL2) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 30. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
1-deoxy-D-xylulose-5-phosphate synthase HAMAP MF_00315
EC=2.2.1.7 HAMAP MF_00315
Alternative name(s):
1-deoxyxylulose-5-phosphate synthase HAMAP MF_00315
Gene names
Name:dxs HAMAP MF_00315
Ordered Locus Names:Clim_1729
OrganismChlorobium limicola (strain DSM 245 / NBRC 103803) [Complete proteome] [HAMAP]
Taxonomic identifier290315 [NCBI]
Taxonomic lineageBacteria › Chlorobi › Chlorobia › Chlorobiales › Chlorobiaceae › Chlorobium/Pelodictyon group › Chlorobium

Protein attributes

Sequence length643 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) By similarity. HAMAP MF_00315 SAAS SAAS005477

Catalytic activity

Pyruvate + D-glyceraldehyde 3-phosphate = 1-deoxy-D-xylulose 5-phosphate + CO2. HAMAP MF_00315 SAAS SAAS005477

Cofactor

Binds 1 thiamine pyrophosphate per subunit By similarity. HAMAP MF_00315 SAAS SAAS005477

Pathway

Metabolic intermediate biosynthesis; 1-deoxy-D-xylulose 5-phosphate biosynthesis; 1-deoxy-D-xylulose 5-phosphate from D-glyceraldehyde 3-phosphate and pyruvate: step 1/1. HAMAP MF_00315 SAAS SAAS005477

Subunit structure

Homodimer By similarity. HAMAP MF_00315 SAAS SAAS005477

Sequence similarities

Belongs to the transketolase family. DXPS subfamily. HAMAP MF_00315

Sequences

Sequence LengthMass (Da)Tools
B3EEG0 [UniParc].

Last modified July 22, 2008. Version 1.
Checksum: 159412D152CE2696

FASTA64369,746
        10         20         30         40         50         60 
MPDTVKLPIH QEKFLLPEIQ SPDDLKKLSI TELQLLAEEC RNEVINLVSE NGGHFASTLG 

        70         80         90        100        110        120 
VVELTVALHH VYNSPQDKII WDVGHQAYVH KILTGRRARM HTNRQYGGLA GFPKITESPY 

       130        140        150        160        170        180 
DAFGTGHAST SISAAAGIAA ARDLAGSGEK VIAVIGDGSM TGGMAFEAMN HLGDLKSDVL 

       190        200        210        220        230        240 
VILNDNQMAI SPSTGGLKTH LINITLNKTY NRTRKFIWNS ISLLNNEFGD AAKNAVRKLE 

       250        260        270        280        290        300 
DGFKAAFTPG AFFEALGLRY FGPIDGHNME QLVKALREMQ ELPHPKLLHI VTTKGKGFKP 

       310        320        330        340        350        360 
AEDNQSKWHA HSGGFDRITG ITPKTDGKPQ PPKYQEIFGE ALVELALKDA RITAITAAMP 

       370        380        390        400        410        420 
SGTSLDLFQN ALPNRFYDVG IAEAHAVTFA AGQATKGFLP VCAIYSTFLQ RAYDQIIHDV 

       430        440        450        460        470        480 
AQQNLHVVFA IDRAGLVGED GPTHHGSFDL SYLHAVPNLT VMMPADEQEL RDMLYTALYE 

       490        500        510        520        530        540 
ISGPVAIRYP RGSGTGVALR KTFTQVETGK GILLREGSKI ALLTAGPLTD MALDVADTLQ 

       550        560        570        580        590        600 
QEGLGVSVAN MRFLKPVDTA LIEKLAGSST HFAVIEENSV IGGLASAVID CLNEQGIARP 

       610        620        630        640 
VLKIGLPDRF ITHGSMAELY RETGMTAEAV LKRIKEFYKG STM

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References

[1]"Complete sequence of Chlorobium limicola DSM 245."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Zhao F., Li T., Liu Z. expand/collapse author list , Overmann J., Bryant D.A., Richardson P.
Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 245 / NBRC 103803.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001097 Genomic DNA. Translation: ACD90770.1.
RefSeqYP_001943749.1. NC_010803.1.

3D structure databases

ProteinModelPortalB3EEG0.
ModBaseSearch...

Protein-protein interaction databases

STRINGB3EEG0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6354557.
GenomeReviewsGene locus Clim_1729 in contig CP001097_GR.
KEGGcli:Clim_1729.
PATRIC21375661. VBIChlLim118737_1854.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG571647.
OMARAHEFES.
ProtClustDBPRK05444.

Family and domain databases

HAMAPMF_00315. DXP_synth.
[Tree]
InterProIPR005477. Dxylulose-5-P_synthase.
IPR011766. TPP_enzyme-bd_C.
IPR009014. Transketo_C/Pyr-ferredox_oxred.
IPR015941. Transketolase-like_C.
IPR005475. Transketolase-like_Pyr-bd.
IPR005476. Transketolase_C.
IPR005474. Transketolase_N.
[Graphical view]
Gene3DG3DSA:3.40.50.920. Transketo_C_like. 1 hit.
KOK01662.
PfamPF02775. TPP_enzyme_C. 1 hit.
PF02779. Transket_pyr. 1 hit.
PF02780. Transketolase_C. 1 hit.
[Graphical view]
SMARTSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMSSF52922. Transketo_C_like. 1 hit.
TIGRFAMsTIGR00204. Dxs. 1 hit.
PROSITEPS00801. TRANSKETOLASE_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB3EEG0_CHLL2
AccessionPrimary (citable) accession number: B3EEG0
Entry history
Integrated into UniProtKB/TrEMBL: July 22, 2008
Last sequence update: July 22, 2008
Last modified: December 14, 2011
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info