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Protein

Dihydrolipoyl dehydrogenase

Gene

Clim_1494

Organism
Chlorobium limicola (strain DSM 245 / NBRC 103803 / 6330)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Catalytic activityi

Protein N(6)-(dihydrolipoyl)lysine + NAD+ = protein N(6)-(lipoyl)lysine + NADH.UniRule annotation

Cofactori

FADUniRule annotationNote: Binds 1 FAD per subunit.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Keywords - Biological processi

GlycolysisSAAS annotation

Keywords - Ligandi

FADUniRule annotation, Flavoprotein, NADUniRule annotation

Enzyme and pathway databases

BioCyciCLIM290315:GHUH-1530-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Dihydrolipoyl dehydrogenaseUniRule annotation (EC:1.8.1.4UniRule annotation)
Gene namesi
Ordered Locus Names:Clim_1494Imported
OrganismiChlorobium limicola (strain DSM 245 / NBRC 103803 / 6330)Imported
Taxonomic identifieri290315 [NCBI]
Taxonomic lineageiBacteriaChlorobiChlorobiaChlorobialesChlorobiaceaeChlorobium/Pelodictyon groupChlorobium
Proteomesi
  • UP000008841 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi290315.Clim_1494.

Structurei

3D structure databases

ProteinModelPortaliB3EDC1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini13 – 333321FAD/NAD-binding_domInterPro annotationAdd
BLAST
Domaini353 – 462110Pyr_redox_dimInterPro annotationAdd
BLAST

Keywords - Domaini

Redox-active centerUniRule annotation

Phylogenomic databases

eggNOGiENOG4107QN2. Bacteria.
COG1249. LUCA.
HOGENOMiHOG000276708.
KOiK00382.
OMAiEMAWFYA.
OrthoDBiPOG091H0239.

Family and domain databases

Gene3Di3.30.390.30. 1 hit.
3.50.50.60. 2 hits.
InterProiIPR023753. FAD/NAD-binding_dom.
IPR016156. FAD/NAD-linked_Rdtase_dimer.
IPR006258. Lipoamide_DH.
IPR004099. Pyr_nucl-diS_OxRdtase_dimer.
IPR012999. Pyr_OxRdtase_I_AS.
[Graphical view]
PfamiPF07992. Pyr_redox_2. 1 hit.
PF02852. Pyr_redox_dim. 1 hit.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 1 hit.
SSF55424. SSF55424. 1 hit.
TIGRFAMsiTIGR01350. lipoamide_DH. 1 hit.
PROSITEiPS00076. PYRIDINE_REDOX_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B3EDC1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQDKMEKRAY DADLAVIGSG PGGYEAALRA ARLGMKVILV EKGSPGGVCV
60 70 80 90 100
NWGCIPTKAL LRSAGMFDDL SKASGYGVLL SDPGFDLAQA VKRSRNVALK
110 120 130 140 150
LSKGIGFMLK KAGVEYRHGE ARLSASHEIS VIRDGEQVGS FTSENIIIAT
160 170 180 190 200
GGRFRELPGL VPDGRRIITS REALALKDVP RSMLVLGGGA IGIEMAWFYA
210 220 230 240 250
KAGTKVTVVE MMPQILPLEE AEIAEGLRRS FEKAGIEIHT SAKLEQLSCR
260 270 280 290 300
ESGVEAVIRK QGEDPLPAEA DCLLVAVGVT GNADGLGLEE AGVEISKGFI
310 320 330 340 350
LTDDQCRTAA DHIFAVGDVR GGMLLAHKAS AEAAIAVAAI AGKPLPALDD
360 370 380 390 400
TKIPRCVYVE PSVASVGLTE ELAKAKGCKV TIGRSMFAAS GKANAYGNLE
410 420 430 440 450
GLVKLVFNAS DLRLLGAHIL GHGAVELIGE IGLARHLEVT AGDIAHAVHA
460 470
HPTLSETIRE AAEYALDTQV SEG
Length:473
Mass (Da):49,649
Last modified:July 22, 2008 - v1
Checksum:i3C1330549F43F66B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001097 Genomic DNA. Translation: ACD90546.1.
RefSeqiWP_012466422.1. NC_010803.1.

Genome annotation databases

EnsemblBacteriaiACD90546; ACD90546; Clim_1494.
KEGGicli:Clim_1494.
PATRICi21375105. VBIChlLim118737_1585.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001097 Genomic DNA. Translation: ACD90546.1.
RefSeqiWP_012466422.1. NC_010803.1.

3D structure databases

ProteinModelPortaliB3EDC1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi290315.Clim_1494.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACD90546; ACD90546; Clim_1494.
KEGGicli:Clim_1494.
PATRICi21375105. VBIChlLim118737_1585.

Phylogenomic databases

eggNOGiENOG4107QN2. Bacteria.
COG1249. LUCA.
HOGENOMiHOG000276708.
KOiK00382.
OMAiEMAWFYA.
OrthoDBiPOG091H0239.

Enzyme and pathway databases

BioCyciCLIM290315:GHUH-1530-MONOMER.

Family and domain databases

Gene3Di3.30.390.30. 1 hit.
3.50.50.60. 2 hits.
InterProiIPR023753. FAD/NAD-binding_dom.
IPR016156. FAD/NAD-linked_Rdtase_dimer.
IPR006258. Lipoamide_DH.
IPR004099. Pyr_nucl-diS_OxRdtase_dimer.
IPR012999. Pyr_OxRdtase_I_AS.
[Graphical view]
PfamiPF07992. Pyr_redox_2. 1 hit.
PF02852. Pyr_redox_dim. 1 hit.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 1 hit.
SSF55424. SSF55424. 1 hit.
TIGRFAMsiTIGR01350. lipoamide_DH. 1 hit.
PROSITEiPS00076. PYRIDINE_REDOX_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiB3EDC1_CHLL2
AccessioniPrimary (citable) accession number: B3EDC1
Entry historyi
Integrated into UniProtKB/TrEMBL: July 22, 2008
Last sequence update: July 22, 2008
Last modified: September 7, 2016
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Miscellaneous

The active site is a redox-active disulfide bond.UniRule annotation

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.