B3ECN9 (ARGB_CHLL2) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Acetylglutamate kinase
EC=2.7.2.8

Alternative name(s):
N-acetyl-L-glutamate 5-phosphotransferase
NAG kinase
Short name=AGK

Gene names

Name:	argB
Ordered Locus Names:	Clim_1247

Organism

Chlorobium limicola (strain DSM 245 / NBRC 103803) [Complete proteome] [HAMAP]

Taxonomic identifier

290315 [NCBI]

Taxonomic lineage

Bacteria › Chlorobi › Chlorobia › Chlorobiales › Chlorobiaceae › Chlorobium/Pelodictyon group › Chlorobium

Protein attributes

Sequence length	304 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamate 5-phosphate. HAMAP MF_00082_B
Pathway	Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 2/4. HAMAP MF_00082_B
Subcellular location	Cytoplasm By similarity HAMAP MF_00082_B.
Sequence similarities	Belongs to the acetylglutamate kinase family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Arginine biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arginine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW acetylglutamate kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 304	304	Acetylglutamate kinase HAMAP MF_00082_B		PRO_1000117121
Regions
	Region	77 – 78	2	Substrate binding By similarity
Sites
	Binding site	99	1	Substrate By similarity
	Binding site	193	1	Substrate By similarity
	Site	42	1	Transition state stabilizer By similarity
	Site	252	1	Transition state stabilizer By similarity

Sequences

	Sequence		Length	Mass (Da)
	B3ECN9 [UniParc]. Last modified July 22, 2008. Version 1. Checksum: ADF69AC5A8D689C3	FASTA	304	32,624
	10 20 30 40 50 60 MNPLCSEFTS SSRKAPEAAI GQVLIEALPY IRKFEGKTFV IKYGGSAMKD ELLKNSFAQN 70 80 90 100 110 120 VTLLRKVGIN VVLVHGGGDA ITRTAEKLGL VSQFVHGKRV TDNDMITVVQ MTLAGKVNQD 130 140 150 160 170 180 IVRLLSEHGG KAVGVTGLDA DTIKAVPGPN AEKLGLVGDV ESINTDYIDL LCRAGLIPVI 190 200 210 220 230 240 APVGYDHNGN IYNINADDAA SSIAIALKAE KLIYVSDVEG IQVGERILKT ICKAEAADFI 250 260 270 280 290 300 EQGIISGGMI PKVLSAFKTL DGGVRKIHLI DGKFTHSLLL EIFTHEGIGT QFIAEQDNDQ QENR

References

[1]

"Complete sequence of Chlorobium limicola DSM 245." US DOE Joint Genome Institute Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Zhao F., Li T., Liu Z. , Overmann J., Bryant D.A., Richardson P. Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 245 / NBRC 103803.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001097 Genomic DNA. Translation: ACD90314.1.
RefSeq	YP_001943293.1. NC_010803.1.
3D structure databases
ProteinModelPortal	B3ECN9.
ModBase	Search...
Protein-protein interaction databases
STRING	B3ECN9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6355348.
GenomeReviews	Gene locus Clim_1247 in contig CP001097_GR.
KEGG	cli:Clim_1247.
PATRIC	21374585. VBIChlLim118737_1330.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG497643.
OMA	GGNAMID.
ProtClustDB	PRK00942.
Family and domain databases
HAMAP	MF_00082_B. ArgB_B. [Tree]
InterPro	IPR004662. AcgluKinase. IPR001048. Asp/Glu/Uridylate_kinase. [Graphical view]
Gene3D	G3DSA:3.40.1160.10. Aa_kinase. 1 hit.
KO	K00930.
Pfam	PF00696. AA_kinase. 1 hit. [Graphical view]
PIRSF	PIRSF000728. NAGK. 1 hit.
SUPFAM	SSF53633. Aa_kinase. 1 hit.
TIGRFAMs	TIGR00761. ArgB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ARGB_CHLL2

Accession

Primary (citable) accession number: B3ECN9

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	July 22, 2008
Last modified:	January 25, 2012
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program