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B3E9N0 (AROC_GEOLS) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Chorismate synthase
EC=4.2.3.5
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate phospholyase
Gene names
Name:aroC
Ordered Locus Names:Glov_1590
OrganismGeobacter lovleyi (strain ATCC BAA-1151 / DSM 17278 / SZ) [Complete proteome] [HAMAP]
Taxonomic identifier398767 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Deltaproteobacteria › Desulfuromonadales › Geobacteraceae › Geobacter

Protein attributes

Sequence length392 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate. HAMAP MF_00300

Cofactor

Reduced flavin By similarity. HAMAP MF_00300

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7. HAMAP MF_00300

Subunit structure

Homotetramer By similarity. HAMAP MF_00300

Sequence similarities

Belongs to the chorismate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionchorismate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 392392Chorismate synthase HAMAP MF_00300
PRO_1000132772

Sequences

Sequence LengthMass (Da)Tools
B3E9N0 [UniParc].

Last modified July 22, 2008. Version 1.
Checksum: 87A2CE543E3DC914

FASTA39242,466
        10         20         30         40         50         60 
MRYITAGESH GPQLTAIIEG LPAGLEISPE MLDLQLARRQ QGYGRGDRMK IERDRADILS 

        70         80         90        100        110        120 
GVRWGKTLGS PVTLVVKNRD WENWLEKMSP LAEHEGQAEA VTRPRPGHAD LCGAMKYGHR 

       130        140        150        160        170        180 
DVRNILERSS ARETAVRVAV GAVARGLLHA LDIRIGGVVV EVGGVAAKPS AEPYPQQWAQ 

       190        200        210        220        230        240 
AAASEMFCCD PAAELDMKRL IDHTKSIGDT LGGVVEVQVL GLPPGLGSHV QWDRKLDARL 

       250        260        270        280        290        300 
AMALMSIQAI KGVEIGLGFE AARRPGSKVH DEITWNPARL QQGELTPYQR PSNHAGGLEG 

       310        320        330        340        350        360 
GMTNGEPLVV RAAMKPIPTL YTPLQSVDIA THEPYEASVE RSDTCAVPAA LVVAEAVVAI 

       370        380        390 
ELAQALLEKF GGDSLDEIRR NRDNYLAGLR DF

« Hide

References

[1]"Complete sequence of chromosome of Geobacter lovleyi SZ."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Meincke L., Brettin T., Detter J.C., Han C., Tapia R., Kuske C.R., Schmutz J., Larimer F. expand/collapse author list , Land M., Hauser L., Kyrpides N., Mikhailova N., Sung Y., Fletcher K.E., Ritalahti K.M., Loeffler F.E., Richardson P.
Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-1151 / DSM 17278 / SZ.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001089 Genomic DNA. Translation: ACD95306.1.
RefSeqYP_001951826.1. NC_010814.1.

3D structure databases

ProteinModelPortalB3E9N0.
SMRB3E9N0. Positions 1-392.
ModBaseSearch...

Protein-protein interaction databases

STRINGB3E9N0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6368248.
GenomeReviewsGene locus Glov_1590 in contig CP001089_GR.
KEGGglo:Glov_1590.
PATRIC21994849. VBIGeoLov31523_1537.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG292336.
OMAMLRWLTA.
ProtClustDBPRK05382.

Family and domain databases

HAMAPMF_00300. Chorismate_synth.
[Tree]
InterProIPR000453. Chorismate_synth.
IPR020541. Chorismate_synthase_CS.
[Graphical view]
KOK01736.
PANTHERPTHR21085. Chorismate_synth. 1 hit.
PfamPF01264. Chorismate_synt. 1 hit.
[Graphical view]
PIRSFPIRSF001456. Chorismate_synth. 1 hit.
SUPFAMSSF103263. Chorismate_synth. 1 hit.
TIGRFAMsTIGR00033. AroC. 1 hit.
PROSITEPS00787. CHORISMATE_SYNTHASE_1. 1 hit.
PS00788. CHORISMATE_SYNTHASE_2. 1 hit.
PS00789. CHORISMATE_SYNTHASE_3. False negative.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROC_GEOLS
AccessionPrimary (citable) accession number: B3E9N0
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: July 22, 2008
Last modified: January 25, 2012
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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