B3E8P0 (B3E8P0_GEOLS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
DNA gyrase subunit B HAMAP MF_01898
EC=5.99.1.3 HAMAP MF_01898

Gene names

Name:	gyrB HAMAP MF_01898
Ordered Locus Names:	Glov_0004

Organism

Geobacter lovleyi (strain ATCC BAA-1151 / DSM 17278 / SZ) [Complete proteome] [HAMAP] EMBL ACD93743.1

Taxonomic identifier

398767 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Deltaproteobacteria › Desulfuromonadales › Geobacteraceae › Geobacter

Protein attributes

Sequence length	802 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings By similarity. HAMAP MF_01898
Catalytic activity	ATP-dependent breakage, passage and rejoining of double-stranded DNA. SAAS SAAS002288 HAMAP MF_01898
Subunit structure	Made up of two chains. The A chain is responsible for DNA breakage and rejoining; the B chain catalyzes ATP hydrolysis. The enzyme forms an A2B2 tetramer By similarity. HAMAP MF_01898
Subcellular location	Cytoplasm By similarity HAMAP MF_01898.
Sequence similarities	Belongs to the type II topoisomerase family. HAMAP MF_01898

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP MF_01898
Ligand	ATP-binding SAAS SAAS002288 HAMAP MF_01898 Nucleotide-binding
Molecular function	Isomerase Topoisomerase SAAS SAAS002288 HAMAP MF_01898
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA topological change Inferred from electronic annotation. Source: InterPro DNA-dependent DNA replication Inferred from electronic annotation. Source: HAMAP
Cellular component	chromosome Inferred from electronic annotation. Source: InterPro cytoplasm Inferred from electronic annotation. Source: HAMAP
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP DNA topoisomerase (ATP-hydrolyzing) activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B3E8P0 [UniParc]. Last modified July 22, 2008. Version 1. Checksum: B3C424A9EAA6A2D0	FASTA	802	89,490
	10 20 30 40 50 60 MSEFEQNGTA ASNEYGAGSI KVLEGLSAVR KRPAMYIGST ASAGLHHLVY EIVDNSIDEA 70 80 90 100 110 120 LAGHCNDVSV TINTDGSITV VDNGRGIPTD MHPTEGRSAA EVVLTVLHAG GKFDNDSYKV 130 140 150 160 170 180 SGGLHGVGVS VVNALSKWLD LEIRRDGKIW RQTYHRGEPQ SPLEVTGTTR RRGTKITFMP 190 200 210 220 230 240 DEEIFETTEY SFDVLSQRLR ELAFLNAGVR IKINDERADG KSHDFFYEGG INSFVEYLNR 250 260 270 280 290 300 AKTPLHQKPI YFKGEKGGVE MEVSMQYNDT YDEKIFSFAN NINTHEGGTH LAGFKAALTR 310 320 330 340 350 360 TMNTYAAGNN LTKNAKVAIS GDDLREGMTC VISVKIPQPQ FEGQTKTKLG NSEVKGYVES 370 380 390 400 410 420 LLNEKLAVYL EENPQVAKRI LEKSIEAARA REAARKARDL TRRKGALDLG GLPGKLADCQ 430 440 450 460 470 480 EKDPALCELY LVEGDSAGGS AKQGRDRRFQ AILPLKGKIL NVEKARFDKM LSSQEIRTLI 490 500 510 520 530 540 TAMGTGIGKD DFDIAKLRYG RIIVMTDADV DGSHILTLLL TFFYRNMQEL IERGHLYIAQ 550 560 570 580 590 600 PPLYKVKRGK KELYLRNEAA LQTFLLEEGA EELILSMEKG DRSYIGKQII PVIRQLIEWR 610 620 630 640 650 660 ALFEKVVKKG IPADLLDLLI RAGVRPGIEE VAGLESYLNT MQGLIDDCDY QYQAEDERVT 670 680 690 700 710 720 FRIGNMRSVI DNQTLGVLAS HEYELLVESN RKVAELMAGG LARLEENGKG LLETSRHEEL 730 740 750 760 770 780 LSYFLDYAKK GLAIQRYKGL GEMNPDQLWE TTMNPENRIL LQVKIEDVVE ADQIFTVLMG 790 800 DQVEPRREFI ELNALNVVNL DV

References

[1]

"Complete sequence of chromosome of Geobacter lovleyi SZ." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Meincke L., Brettin T., Detter J.C., Han C., Tapia R., Kuske C.R., Schmutz J., Larimer F. , Land M., Hauser L., Kyrpides N., Mikhailova N., Sung Y., Fletcher K.E., Ritalahti K.M., Loeffler F.E., Richardson P. Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-1151 / DSM 17278 / SZ.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001089 Genomic DNA. Translation: ACD93743.1.
RefSeq	YP_001950263.1. NC_010814.1.
3D structure databases
ProteinModelPortal	B3E8P0.
ModBase	Search...
Protein-protein interaction databases
STRING	B3E8P0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6366564.
GenomeReviews	Gene locus Glov_0004 in contig CP001089_GR.
KEGG	glo:Glov_0004.
PATRIC	21991745. VBIGeoLov31523_0004.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG304889.
OMA	DCSSRDP.
ProtClustDB	PRK14939.
Family and domain databases
HAMAP	MF_01898. GyrB. [Tree]
InterPro	IPR003594. ATPase-like_ATP-bd. IPR011557. GyrB. IPR020568. Ribosomal_S5_D2-typ_fold. IPR014721. Ribosomal_S5_D2-typ_fold_subgr. IPR001241. Topo_IIA. IPR013759. Topo_IIA_B/N_ab. IPR002288. Topo_IIA_B_C. IPR013506. Topo_IIA_bsu_dom2. IPR013760. Topo_IIA_cen. IPR018522. TopoIIA_CS. [Graphical view]
Gene3D	G3DSA:3.30.565.10. ATP_bd_ATPase. 1 hit. G3DSA:3.30.230.10. Ribosomal_S5_D2-type_fold. 1 hit. G3DSA:3.40.50.670. Topo_IIA_B/N_ab. 2 hits.
KO	K02470.
Pfam	PF00204. DNA_gyraseB. 1 hit. PF00986. DNA_gyraseB_C. 1 hit. PF02518. HATPase_c. 1 hit. [Graphical view]
PRINTS	PR00418. TPI2FAMILY.
SMART	SM00387. HATPase_c. 1 hit. SM00433. TOP2c. 1 hit. [Graphical view]
SUPFAM	SSF55874. ATP_bd_ATPase. 1 hit. SSF54211. Ribosomal_S5_D2-typ_fold. 1 hit. SSF56719. Topo_IIA_cen. 1 hit.
TIGRFAMs	TIGR01059. GyrB. 1 hit.
PROSITE	PS00177. TOPOISOMERASE_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B3E8P0_GEOLS

Accession

Primary (citable) accession number: B3E8P0

Entry history

Integrated into UniProtKB/TrEMBL:	July 22, 2008
Last sequence update:	July 22, 2008
Last modified:	January 25, 2012
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)