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B3E8G1 (B3E8G1_GEOLS) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ferrochelatase HAMAP-Rule MF_00323 RuleBase RU000607
EC=4.99.1.1 HAMAP-Rule MF_00323 RuleBase RU000607
Alternative name(s):
Heme synthase HAMAP-Rule MF_00323
Protoheme ferro-lyase HAMAP-Rule MF_00323
Gene names
Name:hemH HAMAP-Rule MF_00323
Ordered Locus Names:Glov_2930 EMBL ACD96637.1
OrganismGeobacter lovleyi (strain ATCC BAA-1151 / DSM 17278 / SZ) [Complete proteome] [HAMAP] EMBL ACD96637.1
Taxonomic identifier398767 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Deltaproteobacteria › Desulfuromonadales › Geobacteraceae › Geobacter ›

Protein attributes

Sequence length316 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the ferrous insertion into protoporphyrin IX By similarity. HAMAP-Rule MF_00323 SAAS SAAS019772 RuleBase RU000607

Catalytic activity

Protoheme + 2 H+ = protoporphyrin + Fe2+. HAMAP-Rule MF_00323 RuleBase RU000607 SAAS SAAS019772

Pathway

Porphyrin metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1. HAMAP-Rule MF_00323 SAAS SAAS019772 RuleBase RU000607

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00323.

Sequence similarities

Belongs to the ferrochelatase family. HAMAP-Rule MF_00323 RuleBase RU004185

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding1891Iron By similarity HAMAP-Rule MF_00323
Metal binding2681Iron By similarity HAMAP-Rule MF_00323

Sequences

Sequence LengthMass (Da)Tools
B3E8G1 [UniParc].

Last modified July 22, 2008. Version 1.
Checksum: 02E630EB3509AE3E

FASTA31635,427
        10         20         30         40         50         60 
MRDTAIILLQ MGGPDSLEAV RPFLLNLFSD REIIKIGPAW LQPLIARMIV RRRTPAVMEK 

        70         80         90        100        110        120 
YREIGGRSPI QELTRAQADT LAAKLGIPCH VGMRYWHPFT AETLAQLRKT GTKKLVALSL 

       130        140        150        160        170        180 
YPHYSRATSG SSFNDLTRCL ADLDSDLEVV RIPHFYDHPL YIDALTEKIE AGLASFPNRT 

       190        200        210        220        230        240 
GVQLLFSAHS LPQSFIAEGD PYLEHIQATV RLVMERFEGV QHRLAFQSRA GPVKWLEPST 

       250        260        270        280        290        300 
DDTLKELAAN GCKSLLMVPL SFVSDHIETL HEIDIEYAAE AHKIGISDFR RTESLNSSPA 

       310 
FISCLAELVR QALKSH

« Hide

References

[1]"Complete sequence of chromosome of Geobacter lovleyi SZ."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Meincke L., Brettin T., Detter J.C., Han C., Tapia R., Kuske C.R., Schmutz J., Larimer F. expand/collapse author list , Land M., Hauser L., Kyrpides N., Mikhailova N., Sung Y., Fletcher K.E., Ritalahti K.M., Loeffler F.E., Richardson P.
Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-1151 / DSM 17278 / SZ.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001089 Genomic DNA. Translation: ACD96637.1.
RefSeqYP_001953157.1. NC_010814.1.

3D structure databases

ProteinModelPortalB3E8G1.
ModBaseSearch...

Protein-protein interaction databases

STRING398767.Glov_2930.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACD96637; ACD96637; Glov_2930.
GeneID6369048.
KEGGglo:Glov_2930.
PATRIC21997529. VBIGeoLov31523_2861.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0276.
HOGENOMHOG000060727.
KOK01772.
OMAWNNSSEV.
ProtClustDBCLSK790160.

Enzyme and pathway databases

BioCycGLOV398767:GH32-3055-MONOMER.
UniPathwayUPA00252; UER00325.

Family and domain databases

HAMAPMF_00323. Ferrochelatase.
InterProIPR001015. Ferrochelatase.
IPR019772. Ferrochelatase_AS.
[Graphical view]
PANTHERPTHR11108. PTHR11108. 1 hit.
PfamPF00762. Ferrochelatase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00109. hemH. 1 hit.
PROSITEPS00534. FERROCHELATASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB3E8G1_GEOLS
AccessionPrimary (citable) accession number: B3E8G1
Entry history
Integrated into UniProtKB/TrEMBL: July 22, 2008
Last sequence update: July 22, 2008
Last modified: May 1, 2013
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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