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B3E8G1 (B3E8G1_GEOLS) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ferrochelatase HAMAP MF_00323
EC=4.99.1.1 HAMAP MF_00323
Alternative name(s):
Heme synthase HAMAP MF_00323
Protoheme ferro-lyase HAMAP MF_00323
Gene names
Name:hemH HAMAP MF_00323
Ordered Locus Names:Glov_2930
OrganismGeobacter lovleyi (strain ATCC BAA-1151 / DSM 17278 / SZ) [Complete proteome] [HAMAP] EMBL ACD96637.1
Taxonomic identifier398767 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Deltaproteobacteria › Desulfuromonadales › Geobacteraceae › Geobacter

Protein attributes

Sequence length316 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the ferrous insertion into protoporphyrin IX By similarity. HAMAP MF_00323

Catalytic activity

Protoheme + 2 H+ = protoporphyrin + Fe2+. HAMAP MF_00323

Pathway

Porphyrin metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1. HAMAP MF_00323

Subcellular location

Cytoplasm By similarity HAMAP MF_00323.

Sequence similarities

Belongs to the ferrochelatase family. HAMAP MF_00323

Ontologies

Keywords
   Biological processHeme biosynthesis HAMAP MF_00323
Porphyrin biosynthesis HAMAP MF_00323
   Cellular componentCytoplasm HAMAP MF_00323
   LigandIron HAMAP MF_00323
Metal-binding HAMAP MF_00323
   Molecular functionLyase HAMAP MF_00323 EMBL ACD96637.1
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processheme biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionferrochelatase activity

Inferred from electronic annotation. Source: HAMAP

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding1891Iron By similarity HAMAP MF_00323
Metal binding2681Iron By similarity HAMAP MF_00323

Sequences

Sequence LengthMass (Da)Tools
B3E8G1 [UniParc].

Last modified July 22, 2008. Version 1.
Checksum: 02E630EB3509AE3E

FASTA31635,427
        10         20         30         40         50         60 
MRDTAIILLQ MGGPDSLEAV RPFLLNLFSD REIIKIGPAW LQPLIARMIV RRRTPAVMEK 

        70         80         90        100        110        120 
YREIGGRSPI QELTRAQADT LAAKLGIPCH VGMRYWHPFT AETLAQLRKT GTKKLVALSL 

       130        140        150        160        170        180 
YPHYSRATSG SSFNDLTRCL ADLDSDLEVV RIPHFYDHPL YIDALTEKIE AGLASFPNRT 

       190        200        210        220        230        240 
GVQLLFSAHS LPQSFIAEGD PYLEHIQATV RLVMERFEGV QHRLAFQSRA GPVKWLEPST 

       250        260        270        280        290        300 
DDTLKELAAN GCKSLLMVPL SFVSDHIETL HEIDIEYAAE AHKIGISDFR RTESLNSSPA 

       310 
FISCLAELVR QALKSH

« Hide

References

[1]"Complete sequence of chromosome of Geobacter lovleyi SZ."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Meincke L., Brettin T., Detter J.C., Han C., Tapia R., Kuske C.R., Schmutz J., Larimer F. expand/collapse author list , Land M., Hauser L., Kyrpides N., Mikhailova N., Sung Y., Fletcher K.E., Ritalahti K.M., Loeffler F.E., Richardson P.
Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-1151 / DSM 17278 / SZ.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001089 Genomic DNA. Translation: ACD96637.1.
RefSeqYP_001953157.1. NC_010814.1.

3D structure databases

ProteinModelPortalB3E8G1.
ModBaseSearch...

Protein-protein interaction databases

STRINGB3E8G1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6369048.
GenomeReviewsGene locus Glov_2930 in contig CP001089_GR.
KEGGglo:Glov_2930.
PATRIC21997529. VBIGeoLov31523_2861.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG697135.
OMALLQMGGP.
ProtClustDBCLSK790160.

Family and domain databases

HAMAPMF_00323. Ferrochelatase.
[Tree]
InterProIPR001015. Ferrochelatase.
IPR019772. Ferrochelatase_AS.
[Graphical view]
KOK01772.
PANTHERPTHR11108. Ferrochelatase. 1 hit.
PfamPF00762. Ferrochelatase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00109. HemH. 1 hit.
PROSITEPS00534. FERROCHELATASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB3E8G1_GEOLS
AccessionPrimary (citable) accession number: B3E8G1
Entry history
Integrated into UniProtKB/TrEMBL: July 22, 2008
Last sequence update: July 22, 2008
Last modified: December 14, 2011
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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