Reviewed, UniProtKB/Swiss-Prot B3E600 (ADD_GEOLS)

Names and origin

Protein names

Recommended name:
    Adenosine deaminase
    EC=3.5.4.4
Alternative name(s):
    Adenosine aminohydrolase

Gene names

Name:	add
Ordered Locus Names:	Glov_1001

Organism

Geobacter lovleyi (strain ATCC BAA-1151 / DSM 17278 / SZ) [Complete proteome] [HAMAP]

Taxonomic identifier

398767 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Deltaproteobacteria › Desulfuromonadales › Geobacteraceae › Geobacter

Protein attributes

Sequence length	349 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Adenosine + H2O = inosine + NH3. HAMAP MF_00540
Sequence similarities	Belongs to the adenosine and AMP deaminases family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	purine ribonucleoside monophosphate biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	adenosine deaminase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 349	349	Adenosine deaminase HAMAP MF_00540		PRO_1000128848
Sites
	Active site	204	1	Potential
	Active site	252	1	Potential
	Active site	285	1	Potential
	Active site	286	1	Potential

Sequences

	Sequence		Length	Mass (Da)
	B3E600-1 [UniParc]. Last modified July 22, 2008. Version 1. Checksum: 14FD3AFC0081076D	FASTA	349	39,130
	10 20 30 40 50 60 MNLTNIPRQA LPELLCRMPK AELHIHIEGS LEPELIFALA ERNRLQLAYP TIESLRAAYA 70 80 90 100 110 120 FTNLQSFLDI YYAGASVLQT EQDFFDMAWA YLLRAKADNV VHAEIFFDPQ THTARGIPFA 130 140 150 160 170 180 TIINGLDRAI QQGRNELGIS AALILCFLRH LTEADAFTVL EEALPFRDKF IGVGLDSGEK 190 200 210 220 230 240 GNPPEKFSRV FARCRELGLR LVAHAGEEGT AEYIWHALDL LQAERIDHGV HCLDDPQLVT 250 260 270 280 290 300 RLVQQQVPLT VCPLSNVKLR VFPDLAAHNI ARLLACGIRA TINSDDPAYF GGYLNQNYLE 310 320 330 340 TFAALPELGA AEAYQLARNS FEASFVDAEV KAGWIRELDQ FFQQQCDKI

References

[1]

"Complete sequence of chromosome of Geobacter lovleyi SZ." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Meincke L., Brettin T., Detter J.C., Han C., Tapia R., Kuske C.R., Schmutz J., Larimer F. , Land M., Hauser L., Kyrpides N., Mikhailova N., Sung Y., Fletcher K.E., Ritalahti K.M., Loeffler F.E., Richardson P. Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP001089 Genomic DNA. Translation: ACD94724.1.
RefSeq	YP_001951244.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	6367699.
GenomeReviews	Gene locus Glov_1001 in contig CP001089_GR.
KEGG	glo:Glov_1001.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	LAQNSLD.
Family and domain databases
HAMAP	MF_00540. [Tree]
InterPro	IPR006650. A/AMP_deam_AS. IPR001365. A/AMP_deaminase. IPR006330. A_deaminase. [Graphical view]
PANTHER	PTHR11409. A/AMP_deaminase. 1 hit.
Pfam	PF00962. A_deaminase. 1 hit. [Graphical view]
TIGRFAMs	TIGR01430. aden_deam. 1 hit.
PROSITE	PS00485. A_DEAMINASE. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ADD_GEOLS

Accession

Primary (citable) accession number: B3E600

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	July 22, 2008
Last modified:	November 3, 2009
This is version 10 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)