B3E400 (B3E400_GEOLS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Porphobilinogen synthase EMBL ACD94414.1
EC=4.2.1.24 EMBL ACD94414.1

Gene names

Ordered Locus Names:

Glov_0688

Organism

Geobacter lovleyi (strain ATCC BAA-1151 / DSM 17278 / SZ) [Complete proteome] [HAMAP] EMBL ACD94414.1

Taxonomic identifier

398767 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Deltaproteobacteria › Desulfuromonadales › Geobacteraceae › Geobacter

Protein attributes

Sequence length	326 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Subunit structure

Homooctamer By similarity. PIRSR PIRSR001415-3

Ontologies

Keywords
Ligand	Magnesium PIRSR PIRSR001415-5 Metal-binding PIRSR PIRSR001415-5 Zinc PIRSR PIRSR001415-3
Molecular function	Lyase EMBL ACD94414.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	porphyrin-containing compound biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW porphobilinogen synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	195	1	Schiff-base intermediate with substrate By similarity PIRSR PIRSR001415-1
	Active site	248	1	Schiff-base intermediate with substrate By similarity PIRSR PIRSR001415-1
	Metal binding	120	1	Zinc; catalytic By similarity PIRSR PIRSR001415-3
	Metal binding	122	1	Zinc; catalytic By similarity PIRSR PIRSR001415-3
	Metal binding	130	1	Zinc; catalytic By similarity PIRSR PIRSR001415-3
	Metal binding	233	1	Magnesium By similarity PIRSR PIRSR001415-5
	Binding site	205	1	Substrate 1 By similarity PIRSR PIRSR001415-2
	Binding site	217	1	Substrate 1 By similarity PIRSR PIRSR001415-2
	Binding site	274	1	Substrate 2 By similarity PIRSR PIRSR001415-2
	Binding site	313	1	Substrate 2 By similarity PIRSR PIRSR001415-2

Sequences

	Sequence		Length	Mass (Da)
	B3E400 [UniParc]. Last modified July 22, 2008. Version 1. Checksum: 4C4931534F8D38BB	FASTA	326	35,967
	10 20 30 40 50 60 MFSSRFRARR IRGKEVFRRM VRETTLSAND LIYPMFSAFG SGIRKEVSSM PGIFQQSIEH 70 80 90 100 110 120 IVAEAKEVHG LGIPAVILFG IPETKDAVGS DAYAEHGIIQ ETIRAIKREV PGLAVITDVC 130 140 150 160 170 180 LCEYTDHGHC GIIKNGDVDN DATVKLLARE ALSHAQAGAD MVAPSDMMDG RVAAIRQTLD 190 200 210 220 230 240 NNGFSHIPVM SYAVKYASGY YGPFREAAES TPQFGDRRSY QMDPANRLEA LREAQADIEE 250 260 270 280 290 300 GADIIMVKPG LPYLDILRDL RNEYAMPLAV YNVSGEYSMI KGAAANGWID EERVVMETML 310 320 GFKRAGADLI ITYHAKDVAR WLKGGI

References

[1]

"Complete sequence of chromosome of Geobacter lovleyi SZ." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Meincke L., Brettin T., Detter J.C., Han C., Tapia R., Kuske C.R., Schmutz J., Larimer F. , Land M., Hauser L., Kyrpides N., Mikhailova N., Sung Y., Fletcher K.E., Ritalahti K.M., Loeffler F.E., Richardson P. Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-1151 / DSM 17278 / SZ.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001089 Genomic DNA. Translation: ACD94414.1.
RefSeq	YP_001950934.1. NC_010814.1.
3D structure databases
ProteinModelPortal	B3E400.
SMR	B3E400. Positions 6-323.
ModBase	Search...
Protein-protein interaction databases
STRING	B3E400.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6369403.
GenomeReviews	Gene locus Glov_0688 in contig CP001089_GR.
KEGG	glo:Glov_0688.
PATRIC	21993067. VBIGeoLov31523_0662.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG285270.
OMA	ADLCFCE.
ProtClustDB	PRK09283.
Family and domain databases
InterPro	IPR013785. Aldolase_TIM. IPR001731. Porphobilinogen_synth. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K01698.
PANTHER	PTHR11458. AlaD_dehydratase. 1 hit.
Pfam	PF00490. ALAD. 1 hit. [Graphical view]
PIRSF	PIRSF001415. Porphbilin_synth. 1 hit.
PRINTS	PR00144. DALDHYDRTASE.
SMART	SM01004. ALAD. 1 hit. [Graphical view]
PROSITE	PS00169. D_ALA_DEHYDRATASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B3E400_GEOLS

Accession

Primary (citable) accession number: B3E400

Entry history

Integrated into UniProtKB/TrEMBL:	July 22, 2008
Last sequence update:	July 22, 2008
Last modified:	January 25, 2012
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)