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B3E3K3

- PUR5_GEOLS

UniProt

B3E3K3 - PUR5_GEOLS

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Protein
Phosphoribosylformylglycinamidine cyclo-ligase
Gene
purM, Glov_2106
Organism
Geobacter lovleyi (strain ATCC BAA-1151 / DSM 17278 / SZ)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoribosylformylglycinamidine cyclo-ligase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. 'de novo' IMP biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Purine biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciGLOV398767:GH32-2140-MONOMER.
UniPathwayiUPA00074; UER00129.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoribosylformylglycinamidine cyclo-ligase (EC:6.3.3.1)
Alternative name(s):
AIR synthase
AIRS
Phosphoribosyl-aminoimidazole synthetase
Gene namesi
Name:purM
Ordered Locus Names:Glov_2106
OrganismiGeobacter lovleyi (strain ATCC BAA-1151 / DSM 17278 / SZ)
Taxonomic identifieri398767 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfuromonadalesGeobacteraceaeGeobacter
ProteomesiUP000002420: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 349349Phosphoribosylformylglycinamidine cyclo-ligaseUniRule annotation
PRO_1000193027Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi398767.Glov_2106.

Structurei

3D structure databases

ProteinModelPortaliB3E3K3.
SMRiB3E3K3. Positions 6-338.

Family & Domainsi

Sequence similaritiesi

Belongs to the AIR synthase family.

Phylogenomic databases

eggNOGiCOG0150.
HOGENOMiHOG000229091.
KOiK01933.
OMAiEFEMYRT.
OrthoDBiEOG61CM1V.

Family and domain databases

Gene3Di3.30.1330.10. 1 hit.
3.90.650.10. 1 hit.
HAMAPiMF_00741_B. AIRS_B.
InterProiIPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view]
PfamiPF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view]
SUPFAMiSSF55326. SSF55326. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsiTIGR00878. purM. 1 hit.

Sequencei

Sequence statusi: Complete.

B3E3K3-1 [UniParc]FASTAAdd to Basket

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MSKPRATYKE AGVDIEAGNS FVQKIKPLVK STFRPEVMTE IGGFGGLFSL    50
NAAKYKNPVL VSGTDGVGTK LKLAFLADRH DTVGIDLVAM CVNDIVVQGA 100
EPLFFLDYLA TGKLDPDKAA QIVAGIAEGC RQAGCALIGG ETAEMPGFYA 150
DGEYDIAGFT VGVVEKDQII DGSSITVGNK LIGIGSSGLH SNGYSLARRI 200
IFDRMGLAIN SPLPDSTKTV DEELLTPTRI YVRSVMNLLK DFRINGIAHI 250
TGGGLLENVP RILPKGCSAS FKLGSWDMPS IFTTLQEAGN VEQNEMYRTF 300
NMGIGMVLAV AAADVDDILS RLNGLGEQAW LIGEVKSMSK NQTEQVVLV 349
Length:349
Mass (Da):37,259
Last modified:July 22, 2008 - v1
Checksum:iE35C904DFA75FA92
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001089 Genomic DNA. Translation: ACD95822.1.
RefSeqiWP_012470161.1. NC_010814.1.
YP_001952342.1. NC_010814.1.

Genome annotation databases

EnsemblBacteriaiACD95822; ACD95822; Glov_2106.
GeneIDi6369342.
KEGGiglo:Glov_2106.
PATRICi21995893. VBIGeoLov31523_2044.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001089 Genomic DNA. Translation: ACD95822.1 .
RefSeqi WP_012470161.1. NC_010814.1.
YP_001952342.1. NC_010814.1.

3D structure databases

ProteinModelPortali B3E3K3.
SMRi B3E3K3. Positions 6-338.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 398767.Glov_2106.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACD95822 ; ACD95822 ; Glov_2106 .
GeneIDi 6369342.
KEGGi glo:Glov_2106.
PATRICi 21995893. VBIGeoLov31523_2044.

Phylogenomic databases

eggNOGi COG0150.
HOGENOMi HOG000229091.
KOi K01933.
OMAi EFEMYRT.
OrthoDBi EOG61CM1V.

Enzyme and pathway databases

UniPathwayi UPA00074 ; UER00129 .
BioCyci GLOV398767:GH32-2140-MONOMER.

Family and domain databases

Gene3Di 3.30.1330.10. 1 hit.
3.90.650.10. 1 hit.
HAMAPi MF_00741_B. AIRS_B.
InterProi IPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view ]
Pfami PF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view ]
SUPFAMi SSF55326. SSF55326. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsi TIGR00878. purM. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-1151 / DSM 17278 / SZ.

Entry informationi

Entry nameiPUR5_GEOLS
AccessioniPrimary (citable) accession number: B3E3K3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: July 22, 2008
Last modified: September 3, 2014
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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