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B3E0T8 (B3E0T8_METI4) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 30. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acetylglutamate kinase HAMAP MF_00082
EC=2.7.2.8 HAMAP MF_00082
Alternative name(s):
N-acetyl-L-glutamate 5-phosphotransferase HAMAP MF_00082
NAG kinase HAMAP MF_00082
Gene names
Name:argB HAMAP MF_00082 EMBL ACD84415.1
Ordered Locus Names:Minf_2361
OrganismMethylacidiphilum infernorum (isolate V4) (Methylokorus infernorum (strain V4)) [Complete proteome] [HAMAP]
Taxonomic identifier481448 [NCBI]
Taxonomic lineageBacteria › Verrucomicrobia › unclassified Verrucomicrobia › Methylacidiphilales › Methylacidiphilaceae › Methylacidiphilum

Protein attributes

Sequence length297 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamate 5-phosphate. HAMAP MF_00082

Pathway

Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 2/4. HAMAP MF_00082

Subcellular location

Cytoplasm By similarity HAMAP MF_00082.

Sequence similarities

Belongs to the acetylglutamate kinase family. HAMAP MF_00082

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region72 – 732Substrate binding By similarity HAMAP MF_00082

Sites

Binding site941Substrate By similarity HAMAP MF_00082
Binding site1921Substrate By similarity HAMAP MF_00082
Site371Transition state stabilizer By similarity HAMAP MF_00082
Site2551Transition state stabilizer By similarity HAMAP MF_00082

Sequences

Sequence LengthMass (Da)Tools
B3E0T8 [UniParc].

Last modified July 22, 2008. Version 1.
Checksum: B1B0A4830D07350E

FASTA29732,670
        10         20         30         40         50         60 
MKEGNFAEEL TPEQKVSIFL EALPYVQKFR EGIFVIKYGG AAMEDPLLVE KTLRDIVLLE 

        70         80         90        100        110        120 
AVGINPLIIH GGGEFINRAM KKKGLSPRFV NGIRVTDKEL ISLIEEVLSK EVGPRIAQKI 

       130        140        150        160        170        180 
NEYGAKAVFI PGQEIFWAER WKAVSEEGIP MDYGYVGTIV GADLQPLLKL LHGQFIAVVS 

       190        200        210        220        230        240 
PLARAANGDI YNVNADVAAS KMAKFIKAKK LIYLTNTNGI LADEKDPLSR ISVINRQQIS 

       250        260        270        280        290 
LLKEKGIIHG GMIPKVDSAL EALEAGVEKV HFLDGRMPHA LLLEIFTDKG IGTEIVL

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References

[1]"Complete genome sequence of the extremely acidophilic methanotroph isolate V4, Methylacidiphilum infernorum, a representative of the bacterial phylum Verrucomicrobia."
Hou S., Makarova K.S., Saw J.H., Senin P., Ly B.V., Zhou Z., Ren Y., Wang J., Galperin M.Y., Omelchenko M.V., Wolf Y.I., Yutin N., Koonin E.V., Stott M.B., Mountain B.W., Crowe M.A., Smirnova A.V., Dunfield P.F. expand/collapse author list , Feng L., Wang L., Alam M.
Biol. Direct 3:26-26(2008) [PubMed: 18593465] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Isolate V4.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000975 Genomic DNA. Translation: ACD84415.1.
RefSeqYP_001941012.1. NC_010794.1.

3D structure databases

ProteinModelPortalB3E0T8.
ModBaseSearch...

Protein-protein interaction databases

STRINGB3E0T8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6353315.
GenomeReviewsGene locus Minf_2361 in contig CP000975_GR.
KEGGmin:Minf_2361.
PATRIC22493991. VBIMetInf111569_2463.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG497643.
OMAGGNAMID.
ProtClustDBCLSK2337883.

Family and domain databases

HAMAPMF_00082_B. ArgB_B.
[Tree]
InterProIPR004662. AcgluKinase.
IPR001048. Asp/Glu/Uridylate_kinase.
IPR001057. Glu/AcGlu_kinase.
[Graphical view]
Gene3DG3DSA:3.40.1160.10. Aa_kinase. 1 hit.
KOK00930.
PfamPF00696. AA_kinase. 1 hit.
[Graphical view]
PIRSFPIRSF000728. NAGK. 1 hit.
PRINTSPR00474. GLU5KINASE.
SUPFAMSSF53633. Aa_kinase. 1 hit.
TIGRFAMsTIGR00761. ArgB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB3E0T8_METI4
AccessionPrimary (citable) accession number: B3E0T8
Entry history
Integrated into UniProtKB/TrEMBL: July 22, 2008
Last sequence update: July 22, 2008
Last modified: December 14, 2011
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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