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B3DX22

- B3DX22_METI4

UniProt

B3DX22 - B3DX22_METI4

Protein

Glutamate decarboxylase

Gene

gadB

Organism
Methylacidiphilum infernorum (isolate V4) (Methylokorus infernorum (strain V4))
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 35 (01 Oct 2014)
      Sequence version 1 (22 Jul 2008)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotation

    GO - Molecular functioni

    1. glutamate decarboxylase activity Source: InterPro
    2. pyridoxal phosphate binding Source: InterPro

    GO - Biological processi

    1. glutamate metabolic process Source: InterPro

    Keywords - Molecular functioni

    DecarboxylaseUniRule annotation, Lyase

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotation

    Enzyme and pathway databases

    BioCyciMINF481448:GJEI-107-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
    Gene namesi
    Name:gadBImported
    Ordered Locus Names:Minf_0102Imported
    OrganismiMethylacidiphilum infernorum (isolate V4) (Methylokorus infernorum (strain V4))Imported
    Taxonomic identifieri481448 [NCBI]
    Taxonomic lineageiBacteriaVerrucomicrobiaunclassified VerrucomicrobiaMethylacidiphilalesMethylacidiphilaceaeMethylacidiphilum
    ProteomesiUP000009149: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi481448.Minf_0102.

    Structurei

    3D structure databases

    ProteinModelPortaliB3DX22.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the group II decarboxylase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0076.
    HOGENOMiHOG000070228.
    KOiK01580.
    OMAiERQTGID.
    OrthoDBiEOG6TFCPW.

    Family and domain databases

    Gene3Di3.40.640.10. 1 hit.
    InterProiIPR010107. Glutamate_decarboxylase.
    IPR002129. PyrdxlP-dep_de-COase.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    [Graphical view]
    PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
    PfamiPF00282. Pyridoxal_deC. 1 hit.
    [Graphical view]
    SUPFAMiSSF53383. SSF53383. 1 hit.
    TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    B3DX22-1 [UniParc]FASTAAdd to Basket

    « Hide

    MVEAVPKYRL PQKGMPPEVA AQLIRDELML EGNPRLNLAT FVTTWMEKEA    50
    RELIAETYDK NLIDKDEYPK TAEIEKRCVR MIARLFHGSD NEKPVGTSTV 100
    GSSEAIMLAG LAMKWNWKKR QKNSGRSFDK PNLVMGTNVQ VVWEKFCRYF 150
    EVEPRFIPVV AGSYVTNPEK VASYLDDNTI GVVAILGTTY SGEFEPIEQI 200
    HEAIKDFCLT RGMKIPLHID AASGGFVAPF IHPELKWDFQ LPLVESINVS 250
    GHKYGLVYPG VGWAIWRTES SLPEELIFKV NYLGGELPTF SLNFSRPGSQ 300
    VIAQYYNFLR LGEEGYIQIL KSMQSISLHL AEKIESLRIF EMISRGKDIP 350
    VICFELKAEE PFSVFDLSHR LREKGWQVPA YFMPPEAQNT AVMRIVIREG 400
    FSRDMADVLF HDIKTAVEEL RTHTLSRQPR KSLRFIH 437
    Length:437
    Mass (Da):49,940
    Last modified:July 22, 2008 - v1
    Checksum:i78994EDDE719411A
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000975 Genomic DNA. Translation: ACD82162.1.
    RefSeqiYP_001938761.1. NC_010794.1.

    Genome annotation databases

    EnsemblBacteriaiACD82162; ACD82162; Minf_0102.
    GeneIDi6351017.
    KEGGimin:Minf_0102.
    PATRICi22489187. VBIMetInf111569_0104.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000975 Genomic DNA. Translation: ACD82162.1 .
    RefSeqi YP_001938761.1. NC_010794.1.

    3D structure databases

    ProteinModelPortali B3DX22.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 481448.Minf_0102.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACD82162 ; ACD82162 ; Minf_0102 .
    GeneIDi 6351017.
    KEGGi min:Minf_0102.
    PATRICi 22489187. VBIMetInf111569_0104.

    Phylogenomic databases

    eggNOGi COG0076.
    HOGENOMi HOG000070228.
    KOi K01580.
    OMAi ERQTGID.
    OrthoDBi EOG6TFCPW.

    Enzyme and pathway databases

    BioCyci MINF481448:GJEI-107-MONOMER.

    Family and domain databases

    Gene3Di 3.40.640.10. 1 hit.
    InterProi IPR010107. Glutamate_decarboxylase.
    IPR002129. PyrdxlP-dep_de-COase.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    [Graphical view ]
    PANTHERi PTHR11999:SF1. PTHR11999:SF1. 1 hit.
    Pfami PF00282. Pyridoxal_deC. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53383. SSF53383. 1 hit.
    TIGRFAMsi TIGR01788. Glu-decarb-GAD. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence of the extremely acidophilic methanotroph isolate V4, Methylacidiphilum infernorum, a representative of the bacterial phylum Verrucomicrobia."
      Hou S., Makarova K.S., Saw J.H., Senin P., Ly B.V., Zhou Z., Ren Y., Wang J., Galperin M.Y., Omelchenko M.V., Wolf Y.I., Yutin N., Koonin E.V., Stott M.B., Mountain B.W., Crowe M.A., Smirnova A.V., Dunfield P.F.
      , Feng L., Wang L., Alam M.
      Biol. Direct 3:26-26(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Isolate V4Imported.

    Entry informationi

    Entry nameiB3DX22_METI4
    AccessioniPrimary (citable) accession number: B3DX22
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 22, 2008
    Last sequence update: July 22, 2008
    Last modified: October 1, 2014
    This is version 35 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3