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Protein

Xylose isomerase

Gene

xylA

Organism
Bifidobacterium longum (strain DJO10A)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotation

Cofactori

Mg2+UniRule annotationNote: Binds 2 magnesium ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei101UniRule annotation1
Active sitei104UniRule annotation1
Metal bindingi232Magnesium 1UniRule annotation1
Metal bindingi268Magnesium 1UniRule annotation1
Metal bindingi268Magnesium 2UniRule annotation1
Metal bindingi271Magnesium 2UniRule annotation1
Metal bindingi296Magnesium 1UniRule annotation1
Metal bindingi307Magnesium 2UniRule annotation1
Metal bindingi309Magnesium 2UniRule annotation1
Metal bindingi340Magnesium 1UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processCarbohydrate metabolism, Xylose metabolism
LigandMagnesium, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotation (EC:5.3.1.5UniRule annotation)
Gene namesi
Name:xylAUniRule annotation
Ordered Locus Names:BLD_1871
OrganismiBifidobacterium longum (strain DJO10A)
Taxonomic identifieri205913 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaBifidobacterialesBifidobacteriaceaeBifidobacterium
Proteomesi
  • UP000002419 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10002002781 – 449Xylose isomeraseAdd BLAST449

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliB3DR33
SMRiB3DR33
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000252293
KOiK01805
OMAiHTFQHEL

Family and domain databases

HAMAPiMF_00455 Xylose_isom_A, 1 hit
InterProiView protein in InterPro
IPR036237 Xyl_isomerase-like_sf
IPR013022 Xyl_isomerase-like_TIM-brl
IPR013452 Xylose_isom_bac
IPR001998 Xylose_isomerase
PANTHERiPTHR32176:SF0 PTHR32176:SF0, 1 hit
PfamiView protein in Pfam
PF01261 AP_endonuc_2, 1 hit
PRINTSiPR00688 XYLOSISMRASE
SUPFAMiSSF51658 SSF51658, 1 hit
TIGRFAMsiTIGR02630 xylose_isom_A, 1 hit
PROSITEiView protein in PROSITE
PS51415 XYLOSE_ISOMERASE, 1 hit

Sequencei

Sequence statusi: Complete.

B3DR33-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLWDVDKIE YVGRAKGPKE DFAFHYYDAD KVVAGKKMKD WLRFGVAWWH
60 70 80 90 100
TFNQELVDPF GTGTAHRPYY KYTDPMDQAL AKVDYAFELF QKLGVEYFCF
110 120 130 140 150
HDRDIAPEGD TLRETNANLD KVVDKIEENM KSTGVKLLWN TSSLFTNPRF
160 170 180 190 200
VSGAATSPFA DIYAYAGGQL KKSLEIGKRL GAENYVFWGG REGYENLWNT
210 220 230 240 250
EMKRETDHIA KFFHMCADYA KEIGFEAQFL IEPKPKEPTL HQYDFDAATA
260 270 280 290 300
IEFLRNHDLT DVFKLNLEGN HANLAGHTYQ HEIRVARESG FLGSLDANQG
310 320 330 340 350
DKLIGWDMDE FPTDLYETVA VMWEVLQAGS IGPHGGLNFD AKPRRTSFYE
360 370 380 390 400
EDLFRSHIAG MDTYAAGLLV ADKMNQDGFI QDLMAERYSS YDSGIGKDID
410 420 430 440
EGNVTLADLE AYSLDKPQSE LIAATKSDHL ESVKATINNY IIDALSEVE
Length:449
Mass (Da):50,918
Last modified:July 22, 2008 - v1
Checksum:i01BA6BD5C6C13937
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000605 Genomic DNA Translation: ACD99316.1
RefSeqiWP_007052420.1, NZ_AABM02000014.1

Genome annotation databases

EnsemblBacteriaiACD99316; ACD99316; BLD_1871
KEGGiblj:BLD_1871

Similar proteinsi

Entry informationi

Entry nameiXYLA_BIFLD
AccessioniPrimary (citable) accession number: B3DR33
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: July 22, 2008
Last modified: April 25, 2018
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
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Main funding by: National Institutes of Health