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B3DN87 (ZDH12_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable S-acyltransferase At3g56920
EC=2.3.1.-
Alternative name(s):
Probable palmitoyltransferase At3g56920
Zinc finger DHHC domain-containing protein At3g56920
Gene names
Ordered Locus Names:At3g56920
ORF Names:T8M16_250
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length338 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

Palmitoyl-CoA + protein-cysteine = S-palmitoyl protein + CoA.

Subcellular location

Membrane; Multi-pass membrane protein Potential.

Domain

The DHHC domain is required for palmitoyltransferase activity By similarity.

Sequence similarities

Belongs to the DHHC palmitoyltransferase family.

Contains 1 DHHC-type zinc finger.

Sequence caution

The sequence CAC00755.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
   Cellular componentMembrane
   DomainTransmembrane
Transmembrane helix
Zinc-finger
   LigandMetal-binding
Zinc
   Molecular functionAcyltransferase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentintegral to membrane

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functiontransferase activity, transferring acyl groups

Inferred from electronic annotation. Source: UniProtKB-KW

zinc ion binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 338338Probable S-acyltransferase At3g56920
PRO_0000363598

Regions

Transmembrane32 – 5221Helical; Potential
Transmembrane68 – 8821Helical; Potential
Transmembrane186 – 20621Helical; Potential
Transmembrane225 – 24521Helical; Potential
Zinc finger142 – 19251DHHC-type

Sites

Active site1721S-palmitoyl cysteine intermediate By similarity

Sequences

Sequence LengthMass (Da)Tools
B3DN87 [UniParc].

Last modified July 22, 2008. Version 1.
Checksum: 7002A20BC3B9D646

FASTA33838,669
        10         20         30         40         50         60 
MSSQNLERQR IYQVWPAKNK FYCGGRLVFG PDASSLLLTT CMIGGPAIAF SIRMAYLISH 

        70         80         90        100        110        120 
RHPFFHSLTL IGAILLTFMA FTFLFLTSSR DPGIIPRNKQ VSEAEIPDVT TQSTEWVTSK 

       130        140        150        160        170        180 
LGSVKLPRTK DVMVNGFTVK VKFCDTCQLY RPPRAFHCSI CNNCVQRFDH HCPWVGQCIA 

       190        200        210        220        230        240 
LRNYPFFVCF LSCSTLLCIY VFVFSWVSML KVHGEFYVVL ADDLILGVLG LYCFVSVWFV 

       250        260        270        280        290        300 
GGLTVFHFYL ICTNQTTCEN FRYHYDKKEN PYRKGILENF KELFFAKIPP PLINFRDWSP 

       310        320        330 
EEEDDVEVGS IASELVRAFG PKDTKMSSGK SDSEARER

« Hide

References

« Hide 'large scale' references
[1]"Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana."
Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B., Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M., Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V., Choisne N., Artiguenave F. expand/collapse author list , Robert C., Brottier P., Wincker P., Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H., Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H., Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A., Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H., Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J., Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B., Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D., de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E., Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G., Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X., Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M., Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B., Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J., Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C., Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y., Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K., Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
Nature 408:820-822(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Arabidopsis ORF clones."
De Los Reyes C., Quan R., Chen H., Bautista V.R., Kim C.J., Ecker J.R.
Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[4]"S-acylation: dynamic control of plant development and sigalling by lipid modification of proteins."
Hemsley P.A., Taylor L., Grierson C.S.
(In) Proceedings of the 18th international conference on Arabidopsis research, abstract#139, Beijing (2007)
Cited for: GENE FAMILY, FUNCTION.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AL390921 Genomic DNA. Translation: CAC00755.1. Sequence problems.
CP002686 Genomic DNA. Translation: AEE79586.1.
BT032875 mRNA. Translation: ACD89065.1.
IPIIPI00539182.
PIRT51280.
RefSeqNP_191251.2. NM_115551.2.
UniGeneAt.50285.

3D structure databases

ModBaseSearch...

Proteomic databases

PaxDbB3DN87.
PRIDEB3DN87.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT3G56920.1; AT3G56920.1; AT3G56920.
GeneID824859.
KEGGath:AT3G56920.

Organism-specific databases

TAIRAt3g56920.

Phylogenomic databases

eggNOGCOG5273.
HOGENOMHOG000242943.
InParanoidQ9LER6.
OMAIRMAYLI.
PhylomeDBB3DN87.
ProtClustDBCLSN2681634.

Gene expression databases

GenevestigatorB3DN87.

Family and domain databases

InterProIPR001594. Znf_DHHC_palmitoyltrfase.
[Graphical view]
PfamPF01529. zf-DHHC. 1 hit.
[Graphical view]
PROSITEPS50216. ZF_DHHC. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameZDH12_ARATH
AccessionPrimary (citable) accession number: B3DN87
Secondary accession number(s): Q9LER6
Entry history
Integrated into UniProtKB/Swiss-Prot: February 10, 2009
Last sequence update: July 22, 2008
Last modified: May 1, 2013
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents