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B3DM90

- B3DM90_RAT

UniProt

B3DM90 - B3DM90_RAT

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Protein
Submitted name:

Ncstn protein

Gene

Ncstn

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. endopeptidase activity Source: Ensembl

GO - Biological processi

  1. beta-amyloid metabolic process Source: Ensembl
  2. epithelial cell proliferation Source: Ensembl
  3. myeloid cell homeostasis Source: Ensembl
  4. protein processing Source: InterPro
  5. T cell proliferation Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Ncstn proteinImported
Submitted name:
Nicastrin, isoform CRA_bImported
Gene namesi
Name:NcstnImported
ORF Names:rCG_20460Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi631418. Ncstn.

Subcellular locationi

GO - Cellular componenti

  1. endoplasmic reticulum Source: Ensembl
  2. extracellular vesicular exosome Source: Ensembl
  3. Golgi apparatus Source: Ensembl
  4. integral component of membrane Source: InterPro
  5. lysosomal membrane Source: Ensembl
  6. plasma membrane Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

GenevestigatoriB3DM90.

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG006497.
KOiK06171.

Family and domain databases

InterProiIPR008710. Nicastrin.
[Graphical view]
PANTHERiPTHR21092. PTHR21092. 1 hit.
PfamiPF05450. Nicastrin. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B3DM90-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MEKLKGETSR IAGLAVTLAK PNSTSSFSPS VQCPNDGFGI YSNSYGPEFA
60 70 80 90 100
HCKKTLWNEL GNGLAYDDFS FPIFLLEDEN ETKVIKQCYQ DHNLGQNGSA
110 120 130 140 150
PSFPLCAMQL FSHMHAVIST ATCMRRSFIQ STFSINPEIV CDPLSDYNVW
160 170 180 190 200
SMLKPINTSG GLEPDVRVVV AATRLDSRSF FWNVAPGAES AVASFVTQLA
210 220 230 240 250
AAEALHKAPD VTTLPRNVMF VFFQGETFDY IGSSRMVYDM ENGKFPVRLE
260 270 280 290 300
NIDSFVELGQ VALRTSLELW MHTDPMSQKN ESVKNQVEDL LVTLEQSGAD
310 320 330 340 350
TPQVVLSRLV QSQALPPSSL QRFLRARNIS GVVLADHSGS FHNRYYQSIY
360 370 380 390 400
DTAENINVTY PESQSPEEDL NFVTDTAKAL ADVATVLARA LYKLAGGTNF
410 420 430 440 450
NNSIQADPQT VTRLLYGFLV RANNSWFQSI LRHDLRSYLD DGPLQHYIAV
460 470 480 490 500
SSPTNTTYVV QYALANLTGK VTNLTQEQCQ DPSKVPNESK DLYEYSWVQG
510 520 530 540 550
PWNSNKTERL PRCVRSTVRL ARALSPAFEL SQWSSTEYST WAESRWKDIQ
560 570 580 590 600
ARIFLIASKE LEFITLIVGF SILVFSLIVT YCINAKADVL FVAPREPGAV

SY
Length:602
Mass (Da):67,170
Last modified:July 22, 2008 - v1
Checksum:i948EF31880423A57
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC167747 mRNA. Translation: AAI67747.1.
CH473985 Genomic DNA. Translation: EDL94676.1.
RefSeqiXP_006250345.1. XM_006250283.1.
UniGeneiRn.51975.

Genome annotation databases

GeneIDi289231.
KEGGirno:289231.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC167747 mRNA. Translation: AAI67747.1 .
CH473985 Genomic DNA. Translation: EDL94676.1 .
RefSeqi XP_006250345.1. XM_006250283.1.
UniGenei Rn.51975.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 289231.
KEGGi rno:289231.

Organism-specific databases

CTDi 23385.
RGDi 631418. Ncstn.

Phylogenomic databases

HOVERGENi HBG006497.
KOi K06171.

Miscellaneous databases

NextBioi 35565078.

Gene expression databases

Genevestigatori B3DM90.

Family and domain databases

InterProi IPR008710. Nicastrin.
[Graphical view ]
PANTHERi PTHR21092. PTHR21092. 1 hit.
Pfami PF05450. Nicastrin. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: BrainImported.
  2. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.

Entry informationi

Entry nameiB3DM90_RAT
AccessioniPrimary (citable) accession number: B3DM90
Entry historyi
Integrated into UniProtKB/TrEMBL: July 22, 2008
Last sequence update: July 22, 2008
Last modified: November 26, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)