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B3DM90

- B3DM90_RAT

UniProt

B3DM90 - B3DM90_RAT

Protein
Submitted name:

Ncstn protein

Gene

Ncstn

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 36 (01 Oct 2014)
      Sequence version 1 (22 Jul 2008)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. endopeptidase activity Source: Ensembl

    GO - Biological processi

    1. beta-amyloid metabolic process Source: Ensembl
    2. epithelial cell proliferation Source: Ensembl
    3. myeloid cell homeostasis Source: Ensembl
    4. protein processing Source: InterPro
    5. T cell proliferation Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Ncstn proteinImported
    Submitted name:
    Nicastrin, isoform CRA_bImported
    Gene namesi
    Name:NcstnImported
    ORF Names:rCG_20460Imported
    OrganismiRattus norvegicus (Rat)Imported
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

    Organism-specific databases

    RGDi631418. Ncstn.

    Subcellular locationi

    GO - Cellular componenti

    1. endoplasmic reticulum Source: Ensembl
    2. Golgi apparatus Source: Ensembl
    3. integral component of membrane Source: InterPro
    4. plasma membrane Source: Ensembl

    Expressioni

    Gene expression databases

    GenevestigatoriB3DM90.

    Family & Domainsi

    Phylogenomic databases

    HOVERGENiHBG006497.
    KOiK06171.

    Family and domain databases

    InterProiIPR008710. Nicastrin.
    [Graphical view]
    PANTHERiPTHR21092. PTHR21092. 1 hit.
    PfamiPF05450. Nicastrin. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B3DM90-1 [UniParc]FASTAAdd to Basket

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    MEKLKGETSR IAGLAVTLAK PNSTSSFSPS VQCPNDGFGI YSNSYGPEFA    50
    HCKKTLWNEL GNGLAYDDFS FPIFLLEDEN ETKVIKQCYQ DHNLGQNGSA 100
    PSFPLCAMQL FSHMHAVIST ATCMRRSFIQ STFSINPEIV CDPLSDYNVW 150
    SMLKPINTSG GLEPDVRVVV AATRLDSRSF FWNVAPGAES AVASFVTQLA 200
    AAEALHKAPD VTTLPRNVMF VFFQGETFDY IGSSRMVYDM ENGKFPVRLE 250
    NIDSFVELGQ VALRTSLELW MHTDPMSQKN ESVKNQVEDL LVTLEQSGAD 300
    TPQVVLSRLV QSQALPPSSL QRFLRARNIS GVVLADHSGS FHNRYYQSIY 350
    DTAENINVTY PESQSPEEDL NFVTDTAKAL ADVATVLARA LYKLAGGTNF 400
    NNSIQADPQT VTRLLYGFLV RANNSWFQSI LRHDLRSYLD DGPLQHYIAV 450
    SSPTNTTYVV QYALANLTGK VTNLTQEQCQ DPSKVPNESK DLYEYSWVQG 500
    PWNSNKTERL PRCVRSTVRL ARALSPAFEL SQWSSTEYST WAESRWKDIQ 550
    ARIFLIASKE LEFITLIVGF SILVFSLIVT YCINAKADVL FVAPREPGAV 600
    SY 602
    Length:602
    Mass (Da):67,170
    Last modified:July 22, 2008 - v1
    Checksum:i948EF31880423A57
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC167747 mRNA. Translation: AAI67747.1.
    CH473985 Genomic DNA. Translation: EDL94676.1.
    RefSeqiXP_006250345.1. XM_006250283.1.
    UniGeneiRn.51975.

    Genome annotation databases

    GeneIDi289231.
    KEGGirno:289231.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC167747 mRNA. Translation: AAI67747.1 .
    CH473985 Genomic DNA. Translation: EDL94676.1 .
    RefSeqi XP_006250345.1. XM_006250283.1.
    UniGenei Rn.51975.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 289231.
    KEGGi rno:289231.

    Organism-specific databases

    CTDi 23385.
    RGDi 631418. Ncstn.

    Phylogenomic databases

    HOVERGENi HBG006497.
    KOi K06171.

    Miscellaneous databases

    NextBioi 35565078.

    Gene expression databases

    Genevestigatori B3DM90.

    Family and domain databases

    InterProi IPR008710. Nicastrin.
    [Graphical view ]
    PANTHERi PTHR21092. PTHR21092. 1 hit.
    Pfami PF05450. Nicastrin. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: BrainImported.
    2. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: BNImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: BNImported.

    Entry informationi

    Entry nameiB3DM90_RAT
    AccessioniPrimary (citable) accession number: B3DM90
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 22, 2008
    Last sequence update: July 22, 2008
    Last modified: October 1, 2014
    This is version 36 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)