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Protein
Submitted name:

LOC100170618 protein

Gene

tgm2

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Cofactori

Note: Binds 1 calcium ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei277 – 2771UniRule annotation
Active sitei335 – 3351UniRule annotation
Active sitei358 – 3581UniRule annotation

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. protein-glutamine gamma-glutamyltransferase activity Source: InterPro

GO - Biological processi

  1. peptide cross-linking Source: InterPro
Complete GO annotation...

Keywords - Ligandi

CalciumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
LOC100170618 proteinImported
Gene namesi
Name:tgm2Imported
Synonyms:LOC100170618Imported
OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)Imported
Taxonomic identifieri8364 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana

Organism-specific databases

XenbaseiXB-GENE-5940894. tgm2.

Interactioni

Protein-protein interaction databases

STRINGi8364.ENSXETP00000037729.

Family & Domainsi

Phylogenomic databases

eggNOGiNOG80379.
HOGENOMiHOG000231695.
HOVERGENiHBG004342.
KOiK05625.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR013808. Transglutaminase_CS.
IPR001102. Transglutaminase_N.
[Graphical view]
PANTHERiPTHR11590. PTHR11590. 1 hit.
PfamiPF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
SMARTiSM00460. TGc. 1 hit.
[Graphical view]
SUPFAMiSSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
PROSITEiPS00547. TRANSGLUTAMINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B3DM72-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEELYLESF DLDCSGNNRS HRTAEATCER LIVRRGQPFQ ITLNFSPRGY
60 70 80 90 100
EEGVDKLSLN AVTGPCPSEE SGTSNHIPVS DALQDGAWSA AITSTDGGTL
110 120 130 140 150
ILSITSPPDA RIGYYNLSLE TSTEYQGSSF QLGSFTLLFN PWCPEDSVYL
160 170 180 190 200
ETEEERKEYV LCQHGIIFQG TKDSVEHVPW NFGQFEDEIL DITLQVLDTS
210 220 230 240 250
PKFLNDSNRD CSRRNDPVYI SRVISAMVNC NDDRGVLFGR WDNKYDDGIS
260 270 280 290 300
PMFWMGSVAI LRRWRKFSCQ AVKYGQCWVY AAVACTVLRC LGIPARVITN
310 320 330 340 350
YNSAHDTNSN LLIEQYLDEH GKRQPKQKEI IWNYHCWTEA WMTRPDLGEA
360 370 380 390 400
YNGWQVVDPT PQEKSEGTYC CGPTPVKAVK EGDLNLKYDV PFVFAEVNAD
410 420 430 440 450
VVYFVQQNDG SVKKTQFISL VGQKISTKAI GKDEREDITL NYKYPEGSED
460 470 480 490 500
ERRVFEKANK QSEAEEERVE TPSDFTIKIK VSEGMNKGSD FDVFAVITNN
510 520 530 540 550
REEEKQCRLM FCARTCSYTG EVGPECGMKD LLNLTLTPQE EKRVPLRILY
560 570 580 590 600
EKYGPTMTEN NTIKLVAMLY DYSSKEIILA VRDIHVKNPS IKIKVLGEPK
610 620 630 640 650
QKRKLVAEIS LKNPLAEPLT GCCFTVEGAG LTAEQLVKTL DCPVEPGQEA
660 670 680 690
KVRVDLMPQL AGKLSLVVDF ESDLLKAVKG YRNIIIAPLP K
Length:691
Mass (Da):77,879
Last modified:July 22, 2008 - v1
Checksum:i7F03CB6BC0080527
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC167727 mRNA. Translation: AAI67727.1.
RefSeqiNP_001123852.1. NM_001130380.1.
UniGeneiStr.16090.

Genome annotation databases

GeneIDi100170618.
KEGGixtr:100170618.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC167727 mRNA. Translation: AAI67727.1.
RefSeqiNP_001123852.1. NM_001130380.1.
UniGeneiStr.16090.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi8364.ENSXETP00000037729.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi100170618.
KEGGixtr:100170618.

Organism-specific databases

CTDi7052.
XenbaseiXB-GENE-5940894. tgm2.

Phylogenomic databases

eggNOGiNOG80379.
HOGENOMiHOG000231695.
HOVERGENiHBG004342.
KOiK05625.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR013808. Transglutaminase_CS.
IPR001102. Transglutaminase_N.
[Graphical view]
PANTHERiPTHR11590. PTHR11590. 1 hit.
PfamiPF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
SMARTiSM00460. TGc. 1 hit.
[Graphical view]
SUPFAMiSSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
PROSITEiPS00547. TRANSGLUTAMINASES. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. NIH - Xenopus Gene Collection (XGC) project
    Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: TestesImported.

Entry informationi

Entry nameiB3DM72_XENTR
AccessioniPrimary (citable) accession number: B3DM72
Entry historyi
Integrated into UniProtKB/TrEMBL: July 22, 2008
Last sequence update: July 22, 2008
Last modified: November 26, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.