B3DJ94 (B3DJ94_DANRE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Knypek EMBL AAI63403.1

Gene names

Name:	gpc4 ZFIN ZDB-GENE-011119-1
Synonyms:	kny EMBL AAI63403.1 ZFIN ZDB-GENE-011119-1

Organism

Danio rerio (Zebrafish) (Brachydanio rerio) EMBL AAI63403.1

Taxonomic identifier

7955 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Cyprinidae › Danio

Protein attributes

Sequence length	557 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Cell surface proteoglycan that bears heparan sulfate By similarity. RuleBase RU003519
Subcellular location	Cell membrane; Lipid-anchor › GPI-anchor By similarity RuleBase RU003519.
Sequence similarities	Belongs to the glypican family. RuleBase RU003518

Ontologies

Keywords
Cellular component	Membrane
PTM	GPI-anchor RuleBase RU003519 Glycoprotein Heparan sulfate RuleBase RU003519 Lipoprotein Proteoglycan
Gene Ontology (GO)
Biological process	convergent extension involved in axis elongation Inferred from genetic interaction. Source: ZFIN convergent extension involved in gastrulation Inferred from mutant phenotype. Source: ZFIN establishment of cell polarity involved in gastrulation cell migration Inferred from mutant phenotype. Source: ZFIN gastrulation with mouth forming second Inferred from mutant phenotype. Source: ZFIN muscle cell migration Inferred from mutant phenotype. Source: ZFIN protein localization Inferred from genetic interaction. Source: ZFIN regulation of cell migration Inferred from genetic interaction. Source: ZFIN striated muscle cell development Inferred from mutant phenotype. Source: ZFIN unidimensional cell growth Inferred from mutant phenotype. Source: ZFIN
Cellular component	anchored to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell proteinaceous extracellular matrix Inferred from electronic annotation. Source: InterPro
Molecular function	heparan sulfate proteoglycan binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B3DJ94 [UniParc]. Last modified July 22, 2008. Version 1. Checksum: B36BC1A606BCB1E8	FASTA	557	62,206
	10 20 30 40 50 60 MKMIVVFTVC MSVVVLASAQ ADQKSKNCNE VRTAYSSKGF NVNDVPNKGV QGAHLKVCPQ 70 80 90 100 110 120 GFSCCTLEME EKLSQLSRVD LKVPVHQLSS NLQSTFTQRH RHFDQFFREL LDNAEKSLNH 130 140 150 160 170 180 MFVRTYGLMY VKNKELFEGF FSDLRRYYSH GSSEVNLDDM LAEFWSELLE RMFRLVNVQY 190 200 210 220 230 240 EFSDSYMECV SRHTDQLKPF GDVPRKLRLQ LTRSFIAVRA FTRGLTLMPD VVRKVSTVSA 250 260 270 280 290 300 SPSCVRASMK MLYCPYCSGQ VALKPCKNYC LNVMRGCLAN QADLDTEWNN FLDSMLGLAE 310 320 330 340 350 360 RLEGPFNFES VVDPIDVKIS DAIMNMQENS MQVSQKVFQG CGQPKLSMGF RSRRSAKDSG 370 380 390 400 410 420 FPGRFRPYSP EARPTTAAGT TLDRLLTDVK KKLKHAKKFW STLPDTVCVG ERIAPSDDCW 430 440 450 460 470 480 NGTAKSRYES VVMSSGLANQ VSNPDVEVDI TKPDMVIRRQ IAVLKEMTSW LKAAYTGNDI 490 500 510 520 530 540 SFTSDDAGSG EESGSGCDSP SCEGDGDIYF STPAPGKPRI LKTPEVEQAS SGTRLAPCSL 550 ALALASLLLT LLTLQTR

References

[1]	NIH - Zebrafish Gene Collection (ZGC) project Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Pooled EMBL AAI63403.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC163403 mRNA. Translation: AAI63403.1.
IPI	IPI00495453.
RefSeq	NP_571935.2. NM_131860.2.
UniGene	Dr.78935.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B3DJ94.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	118437.
KEGG	dre:118437.
Organism-specific databases
CTD	2239.
ZFIN	ZDB-GENE-011119-1. gpc4.
Phylogenomic databases
HOGENOM	HBG713994.
HOVERGEN	HBG003464.
OrthoDB	EOG4THVT1.
Gene expression databases
Bgee	B3DJ94.
Family and domain databases
InterPro	IPR001863. Glypican. [Graphical view]
KO	K08113.
PANTHER	PTHR10822. Glypican. 1 hit.
Pfam	PF01153. Glypican. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B3DJ94_DANRE

Accession

Primary (citable) accession number: B3DJ94

Entry history

Integrated into UniProtKB/TrEMBL:	July 22, 2008
Last sequence update:	July 22, 2008
Last modified:	November 16, 2011
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)