B3DFK5 (B3DFK5_DANRE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Protein Wnt RuleBase RU003503

Gene names

Name:	wnt2ba ZFIN ZDB-GENE-030717-2 Ensembl ENSDARP00000094209
Synonyms:	wnt2b ZFIN ZDB-GENE-030717-2 EMBL AAI62076.1

Organism

Danio rerio (Zebrafish) (Brachydanio rerio) EMBL AAI62076.1

Taxonomic identifier

7955 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Cyprinidae › Danio

Protein attributes

Sequence length	387 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Ligand for members of the frizzled family of seven transmembrane receptors By similarity. RuleBase RU003500
Subcellular location	Secreted › extracellular space › extracellular matrix By similarity RuleBase RU003500.
Sequence similarities	Belongs to the Wnt family. RuleBase RU003500

Ontologies

Keywords
Biological process	Wnt signaling pathway SAAS SAAS005817 RuleBase RU003500
Cellular component	Extracellular matrix SAAS SAAS005817 Secreted
Molecular function	Developmental protein SAAS SAAS005817 RuleBase RU003500
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	Wnt receptor signaling pathway Inferred from electronic annotation. Source: UniProtKB-KW embryonic pectoral fin morphogenesis Inferred from mutant phenotype. Source: ZFIN
Cellular component	proteinaceous extracellular matrix Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	receptor binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B3DFK5 [UniParc]. Last modified July 22, 2008. Version 1. Checksum: F7795A41A13A1495	FASTA	387	44,097
	10 20 30 40 50 60 MPECDGVGCA SPARKDRQRA RGGFLSRRER RGATQRIYLL FILLLLMFTP SVDSSWWYIG 70 80 90 100 110 120 ALGARVICDN IPGLVNKQRQ LCQRHPDLMQ SIGQGAKEWI RECQHQFRHH RWNCSTLERD 130 140 150 160 170 180 HTVFGRVMLR SSREAAFVYA ISSAGVVYAI TRACSQGELK ICSCDSQRRG RASDEDGDFD 190 200 210 220 230 240 WGGCSDNINY GIKFAKAFVD ARERMVKDAR ALMNLHNNRC GRMAVKRFMK TECKCHGVSG 250 260 270 280 290 300 SCALRTCWLA MSDFRRTGDY LRKKYNAAVE VMMNQDGTGF MVADRDYKRT TKNDLVYIEN 310 320 330 340 350 360 SPDYCLMDRS AGSLGTSGRV CNKSSRGMDG CEIMCCGRGY DTTRVNRMTK CECKFKWCCA 370 380 VECRDCEETV DVHTCKLHKK PDWLDLT

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	NIH - Zebrafish Gene Collection (ZGC) project Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Pooled EMBL AAI62076.1.
[2]	"The genomic sequence of Danio rerio." The Danio rerio Sequencing Project at the Sanger Institute Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Tuebingen Ensembl ENSDARP00000094209.
[3]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: Tuebingen Ensembl ENSDARP00000094209.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR382321 Genomic DNA. No translation available. BC162076 mRNA. Translation: AAI62076.1. BC162077 mRNA. Translation: AAI62077.1.
IPI	IPI00495236.
UniGene	Dr.88309.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B3DFK5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSDART00000103433; ENSDARP00000094209; ENSDARG00000005050.
Organism-specific databases
ZFIN	ZDB-GENE-030717-2. wnt2ba.
Phylogenomic databases
HOGENOM	HBG446188.
HOVERGEN	HBG001595.
OMA	CCAVECS.
OrthoDB	EOG45DWPP.
Gene expression databases
Bgee	B3DFK5.
Family and domain databases
InterPro	IPR005817. Wnt. IPR009140. Wnt2. IPR018161. Wnt_grthfactor_CS. [Graphical view]
PANTHER	PTHR12027. Wnt. 1 hit.
Pfam	PF00110. wnt. 1 hit. [Graphical view]
PRINTS	PR01842. WNT2PROTEIN. PR01349. WNTPROTEIN.
SMART	SM00097. WNT1. 1 hit. [Graphical view]
PROSITE	PS00246. WNT1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B3DFK5_DANRE

Accession

Primary (citable) accession number: B3DFK5

Entry history

Integrated into UniProtKB/TrEMBL:	July 22, 2008
Last sequence update:	July 22, 2008
Last modified:	January 25, 2012
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)