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B3CUQ0

- B3CUQ0_ORITI

UniProt

B3CUQ0 - B3CUQ0_ORITI

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Protein
Submitted name:

Isocitrate dehydrogenase

Gene

icd

Organism
Orientia tsutsugamushi (strain Ikeda) (Rickettsia tsutsugamushi)
Status
Unreviewed - Annotation score: 1 out of 5- Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: InterPro
  2. magnesium ion binding Source: InterPro
  3. NAD binding Source: InterPro

GO - Biological processi

  1. glyoxylate cycle Source: InterPro
  2. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Enzyme and pathway databases

BioCyciOTSU334380:GC7O-1670-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Isocitrate dehydrogenaseImported
Gene namesi
Name:icdImported
Ordered Locus Names:OTT_1639Imported
OrganismiOrientia tsutsugamushi (strain Ikeda) (Rickettsia tsutsugamushi)Imported
Taxonomic identifieri334380 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeOrientia
ProteomesiUP000001033: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi334380.OTT_1639.

Family & Domainsi

Sequence similaritiesi

Belongs to the isocitrate and isopropylmalate dehydrogenases family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0473.
HOGENOMiHOG000021113.
KOiK00031.
OMAiGRANEGT.
OrthoDBiEOG65XN31.

Family and domain databases

Gene3Di3.40.718.10. 1 hit.
InterProiIPR001804. Isocitrate/isopropylmalate_DH.
IPR014273. Isocitrate_DH_aproteobac-typ.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERiPTHR11835. PTHR11835. 1 hit.
PfamiPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02924. ICDH_alpha. 1 hit.

Sequencei

Sequence statusi: Complete.

B3CUQ0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKNVIPVTIA YGDGIGPEIM EAVVYVLKEA AVPLRLETIE IGEKLYNKYY
60 70 80 90 100
TYGITEDTWS QIFRTKALLK GPVTTPQGEG YKSLNVTLKK TLGLYANVRP
110 120 130 140 150
SISYFPFVNT SAPEIDVVII RENEEDLYTG IEYHHTADTY ESIKLISRSG
160 170 180 190 200
SEKIIRFAFE YALKNNRKKI SCFSKDNIMK FTDGIFHNTF NEIASQYSNI
210 220 230 240 250
QVDHYLIDIG SARLISSPQK FDVIVTSNLY GDILSDIAAE ISDSIGLAGS
260 270 280 290 300
ANIGKDYAMF EAVHGSAPDI AGQNIANPSG LLNAAIMMLV HLGLTEHAAK
310 320 330 340 350
IENALKKTIE DGIHTADIYN PSISSKKVGT KEFAQAIINN LEYKPKKLKI
360 370 380 390 400
AEYHNLDVES NIINNSQIQT ITETRQQKKL VGVDVFFDSH NIIDYHRITK
410 420 430 440 450
QLTKRIASLS SLHGMHLVTI SAKGLKLWPN STVREMFSDH WCCRFMVQSS
460 470 480 490 500
GKDKTVTAKN LTMKDILSLL NDLVATINNP IHSESKDDNY DNSIKFELIK
510
VENLYLFNDT VGFSLAQGE
Length:519
Mass (Da):58,017
Last modified:July 22, 2008 - v1
Checksum:iDEBA2724BB059684
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008981 Genomic DNA. Translation: BAG41097.1.
RefSeqiWP_012462089.1. NC_010793.1.
YP_001938331.1. NC_010793.1.

Genome annotation databases

EnsemblBacteriaiBAG41097; BAG41097; OTT_1639.
GeneIDi6337851.
KEGGiott:OTT_1639.
PATRICi22829652. VBIOriTsu129072_1835.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008981 Genomic DNA. Translation: BAG41097.1 .
RefSeqi WP_012462089.1. NC_010793.1.
YP_001938331.1. NC_010793.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 334380.OTT_1639.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAG41097 ; BAG41097 ; OTT_1639 .
GeneIDi 6337851.
KEGGi ott:OTT_1639.
PATRICi 22829652. VBIOriTsu129072_1835.

Phylogenomic databases

eggNOGi COG0473.
HOGENOMi HOG000021113.
KOi K00031.
OMAi GRANEGT.
OrthoDBi EOG65XN31.

Enzyme and pathway databases

BioCyci OTSU334380:GC7O-1670-MONOMER.

Family and domain databases

Gene3Di 3.40.718.10. 1 hit.
InterProi IPR001804. Isocitrate/isopropylmalate_DH.
IPR014273. Isocitrate_DH_aproteobac-typ.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
PANTHERi PTHR11835. PTHR11835. 1 hit.
Pfami PF00180. Iso_dh. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR02924. ICDH_alpha. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The whole-genome sequencing of the obligate intracellular bacterium Orientia tsutsugamushi revealed massive gene amplification during reductive genome evolution."
    Nakayama K., Yamashita A., Kurokawa K., Morimoto T., Ogawa M., Fukuhara M., Urakami H., Ohnishi M., Uchiyama I., Ogura Y., Ooka T., Oshima K., Tamura A., Hattori M., Hayashi T.
    DNA Res. 15:185-199(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: IkedaImported.

Entry informationi

Entry nameiB3CUQ0_ORITI
AccessioniPrimary (citable) accession number: B3CUQ0
Entry historyi
Integrated into UniProtKB/TrEMBL: July 22, 2008
Last sequence update: July 22, 2008
Last modified: October 1, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3