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B3CUQ0

- B3CUQ0_ORITI

UniProt

B3CUQ0 - B3CUQ0_ORITI

Protein
Submitted name:

Isocitrate dehydrogenase

Gene

icd

Organism
Orientia tsutsugamushi (strain Ikeda) (Rickettsia tsutsugamushi)
Status
Unreviewed - Annotation score: 1 out of 5- Protein inferred from homologyi
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    • History
      Entry version 38 (01 Oct 2014)
      Sequence version 1 (22 Jul 2008)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. isocitrate dehydrogenase (NADP+) activity Source: InterPro
    2. magnesium ion binding Source: InterPro
    3. NAD binding Source: InterPro

    GO - Biological processi

    1. glyoxylate cycle Source: InterPro
    2. tricarboxylic acid cycle Source: InterPro

    Enzyme and pathway databases

    BioCyciOTSU334380:GC7O-1670-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Isocitrate dehydrogenaseImported
    Gene namesi
    Name:icdImported
    Ordered Locus Names:OTT_1639Imported
    OrganismiOrientia tsutsugamushi (strain Ikeda) (Rickettsia tsutsugamushi)Imported
    Taxonomic identifieri334380 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeOrientia
    ProteomesiUP000001033: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi334380.OTT_1639.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the isocitrate and isopropylmalate dehydrogenases family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0473.
    HOGENOMiHOG000021113.
    KOiK00031.
    OMAiGRANEGT.
    OrthoDBiEOG65XN31.

    Family and domain databases

    Gene3Di3.40.718.10. 1 hit.
    InterProiIPR001804. Isocitrate/isopropylmalate_DH.
    IPR014273. Isocitrate_DH_aproteobac-typ.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view]
    PANTHERiPTHR11835. PTHR11835. 1 hit.
    PfamiPF00180. Iso_dh. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR02924. ICDH_alpha. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    B3CUQ0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKNVIPVTIA YGDGIGPEIM EAVVYVLKEA AVPLRLETIE IGEKLYNKYY    50
    TYGITEDTWS QIFRTKALLK GPVTTPQGEG YKSLNVTLKK TLGLYANVRP 100
    SISYFPFVNT SAPEIDVVII RENEEDLYTG IEYHHTADTY ESIKLISRSG 150
    SEKIIRFAFE YALKNNRKKI SCFSKDNIMK FTDGIFHNTF NEIASQYSNI 200
    QVDHYLIDIG SARLISSPQK FDVIVTSNLY GDILSDIAAE ISDSIGLAGS 250
    ANIGKDYAMF EAVHGSAPDI AGQNIANPSG LLNAAIMMLV HLGLTEHAAK 300
    IENALKKTIE DGIHTADIYN PSISSKKVGT KEFAQAIINN LEYKPKKLKI 350
    AEYHNLDVES NIINNSQIQT ITETRQQKKL VGVDVFFDSH NIIDYHRITK 400
    QLTKRIASLS SLHGMHLVTI SAKGLKLWPN STVREMFSDH WCCRFMVQSS 450
    GKDKTVTAKN LTMKDILSLL NDLVATINNP IHSESKDDNY DNSIKFELIK 500
    VENLYLFNDT VGFSLAQGE 519
    Length:519
    Mass (Da):58,017
    Last modified:July 22, 2008 - v1
    Checksum:iDEBA2724BB059684
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP008981 Genomic DNA. Translation: BAG41097.1.
    RefSeqiWP_012462089.1. NC_010793.1.
    YP_001938331.1. NC_010793.1.

    Genome annotation databases

    EnsemblBacteriaiBAG41097; BAG41097; OTT_1639.
    GeneIDi6337851.
    KEGGiott:OTT_1639.
    PATRICi22829652. VBIOriTsu129072_1835.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP008981 Genomic DNA. Translation: BAG41097.1 .
    RefSeqi WP_012462089.1. NC_010793.1.
    YP_001938331.1. NC_010793.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 334380.OTT_1639.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAG41097 ; BAG41097 ; OTT_1639 .
    GeneIDi 6337851.
    KEGGi ott:OTT_1639.
    PATRICi 22829652. VBIOriTsu129072_1835.

    Phylogenomic databases

    eggNOGi COG0473.
    HOGENOMi HOG000021113.
    KOi K00031.
    OMAi GRANEGT.
    OrthoDBi EOG65XN31.

    Enzyme and pathway databases

    BioCyci OTSU334380:GC7O-1670-MONOMER.

    Family and domain databases

    Gene3Di 3.40.718.10. 1 hit.
    InterProi IPR001804. Isocitrate/isopropylmalate_DH.
    IPR014273. Isocitrate_DH_aproteobac-typ.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view ]
    PANTHERi PTHR11835. PTHR11835. 1 hit.
    Pfami PF00180. Iso_dh. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR02924. ICDH_alpha. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The whole-genome sequencing of the obligate intracellular bacterium Orientia tsutsugamushi revealed massive gene amplification during reductive genome evolution."
      Nakayama K., Yamashita A., Kurokawa K., Morimoto T., Ogawa M., Fukuhara M., Urakami H., Ohnishi M., Uchiyama I., Ogura Y., Ooka T., Oshima K., Tamura A., Hattori M., Hayashi T.
      DNA Res. 15:185-199(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: IkedaImported.

    Entry informationi

    Entry nameiB3CUQ0_ORITI
    AccessioniPrimary (citable) accession number: B3CUQ0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 22, 2008
    Last sequence update: July 22, 2008
    Last modified: October 1, 2014
    This is version 38 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3