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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Orientia tsutsugamushi (strain Ikeda) (Rickettsia tsutsugamushi)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciOTSU334380:G1G2K-1087-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:OTT_0975
OrganismiOrientia tsutsugamushi (strain Ikeda) (Rickettsia tsutsugamushi)
Taxonomic identifieri334380 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeOrientia
Proteomesi
  • UP000001033 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000953861 – 590Arginine--tRNA ligaseAdd BLAST590

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliB3CST6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi138 – 148"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000247214
KOiK01887
OMAiNKPLHLG
OrthoDBiPOG091H01RF

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.701 hit
3.40.50.6201 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

B3CST6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNIYKRLKQD IDVVATSIIN KLKSTSDSKK FDSLNDTIPI VLESSKDVNS
60 70 80 90 100
YDISTNIAML IAKKMNQNSI TLANLFKKKL SHYPYIANIT IAGPGFINFV
110 120 130 140 150
ILQEAWTNYL AIILDGSYRK EYSSIGNNKK VNIEYVSANP TGPLHIGHAR
160 170 180 190 200
AAVYGDVLAT LLQCTGYQVT REYYVNDTGV QIDNLSKSVY LRYKQAITGQ
210 220 230 240 250
AADIPKGLYP GEYLISVGTN LAEEYGDKLL TLSEPEYLNI IKDVAVNNLL
260 270 280 290 300
QSIKADLALI GVRHDVFFSE KKLHDSNVIS KVIDLLSVKK LVYTGKLSQP
310 320 330 340 350
KGQSSDNWQP RSQLLFKSTI FGDDQDRPLQ KEDGSWSYFA SDIAYADNKI
360 370 380 390 400
KRGFDYVIFI LGADHIGYVS RIKAIIQALD SNQDVTLDIK ICQLVKLIED
410 420 430 440 450
GVAVKMSKRS GSFTTIRDVY ETVGKDVIRF FMLTRKNNAV LDFDLVKLQE
460 470 480 490 500
QSRDNPVFYV QYAYVRAGSI LRKAKDNANI AYEIFSTNKS DFSLLSTKEE
510 520 530 540 550
LNLIKILAVW SHMLDGAVKN FEPHRIAIYL QKLAAEFHAL WNLKSRDLDY
560 570 580 590
RFIVLNDNNL TAARLALATA VREIIREGLK IIGITCVEVM
Length:590
Mass (Da):66,436
Last modified:July 22, 2008 - v1
Checksum:i45AAA00D797C1ED3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008981 Genomic DNA Translation: BAG40433.1
RefSeqiWP_012461558.1, NC_010793.1

Genome annotation databases

EnsemblBacteriaiBAG40433; BAG40433; OTT_0975
KEGGiott:OTT_0975

Similar proteinsi

Entry informationi

Entry nameiSYR_ORITI
AccessioniPrimary (citable) accession number: B3CST6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: July 22, 2008
Last modified: February 28, 2018
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome