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Protein
Submitted name:

Isocitrate dehydrogenase, NAD-dependent

Gene

WP0547

Organism
Wolbachia pipientis subsp. Culex pipiens (strain wPip)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: InterPro
  2. magnesium ion binding Source: InterPro
  3. NAD binding Source: InterPro

GO - Biological processi

  1. glyoxylate cycle Source: InterPro
  2. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Enzyme and pathway databases

BioCyciWEND570417:GHSW-553-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Isocitrate dehydrogenase, NAD-dependentImported
Gene namesi
Ordered Locus Names:WP0547Imported
OrganismiWolbachia pipientis subsp. Culex pipiens (strain wPip)Imported
Taxonomic identifieri570417 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesAnaplasmataceaeWolbachieaeWolbachia
ProteomesiUP000008814: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi570417.WPa_0547.

Family & Domainsi

Sequence similaritiesi

Belongs to the isocitrate and isopropylmalate dehydrogenases family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0473.
KOiK00031.
OMAiRDIKFNE.
OrthoDBiEOG65XN31.

Family and domain databases

Gene3Di3.40.718.10. 1 hit.
InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR014273. Isocitrate_DH_aproteobac-typ.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERiPTHR11835. PTHR11835. 1 hit.
PfamiPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02924. ICDH_alpha. 1 hit.
PROSITEiPS00470. IDH_IMDH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B3CQ02-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSTSVTVAYG DGIGPEIMEA VLSILREAKA EISIDIIEIG ERVYSKEWSH
60 70 80 90 100
GISPSGWESI ERTKILLKSP TTTPQGKGHK SLNVALRKNL GLYANIRPCI
110 120 130 140 150
SYHPVIENKF DKFDVVVIRE NEEDVYTGIE HRLTGDSYQC TKIITRSGSE
160 170 180 190 200
KICRYAFEYA KKHNRKKVTC LTKDNIMKMT DGAFHAAFDR IAKEYPDIKA
210 220 230 240 250
EHYIVDIGMA RVATEPENFD VIVTENLYGD ILSDIVAQTS GSVGLAGSSN
260 270 280 290 300
IGNEYAMFEA VHGSAPDIAG KNIANPSGLL NAAVHMLVYI GQVSTAKLIY
310 320 330 340 350
DAWLKTLEDG VHTADLYKEK KSKQKVGTKE FAKAVIDNLG KKPTTLSELI
360 370 380 390 400
ISSDSDSKIN KVQDNYEQDY KVKKLVGSDI TLAWDKSNNF DQIVRLFESS
410 420 430 440 450
NLKMIAIYSK GLAIWPGGSK SSSDQIICRF IANNEITNSD VNNLLIKFEE
460 470
HNFDVVRMDK LYLYDGKEGF FS
Length:472
Mass (Da):52,574
Last modified:July 22, 2008 - v1
Checksum:i0D2A347C77E009AE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM999887 Genomic DNA. Translation: CAQ54655.1.
RefSeqiYP_001975320.1. NC_010981.1.

Genome annotation databases

EnsemblBacteriaiCAQ54655; CAQ54655; WP0547.
GeneIDi6385485.
KEGGiwpi:WPa_0547.
PATRICi24026712. VBIWolEnd95846_0605.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM999887 Genomic DNA. Translation: CAQ54655.1.
RefSeqiYP_001975320.1. NC_010981.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi570417.WPa_0547.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAQ54655; CAQ54655; WP0547.
GeneIDi6385485.
KEGGiwpi:WPa_0547.
PATRICi24026712. VBIWolEnd95846_0605.

Phylogenomic databases

eggNOGiCOG0473.
KOiK00031.
OMAiRDIKFNE.
OrthoDBiEOG65XN31.

Enzyme and pathway databases

BioCyciWEND570417:GHSW-553-MONOMER.

Family and domain databases

Gene3Di3.40.718.10. 1 hit.
InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR014273. Isocitrate_DH_aproteobac-typ.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERiPTHR11835. PTHR11835. 1 hit.
PfamiPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02924. ICDH_alpha. 1 hit.
PROSITEiPS00470. IDH_IMDH. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: wPipImported.

Entry informationi

Entry nameiB3CQ02_WOLPP
AccessioniPrimary (citable) accession number: B3CQ02
Entry historyi
Integrated into UniProtKB/TrEMBL: July 22, 2008
Last sequence update: July 22, 2008
Last modified: January 7, 2015
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.