Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

B3CNF3 (SYR_WOLPP) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:WP1227
OrganismWolbachia pipientis subsp. Culex pipiens (strain wPip) [Complete proteome] [HAMAP]
Taxonomic identifier570417 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesAnaplasmataceaeWolbachieaeWolbachia

Protein attributes

Sequence length566 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 566566Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_1000095419

Regions

Motif129 – 13911"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
B3CNF3 [UniParc].

Last modified July 22, 2008. Version 1.
Checksum: CEA1050EEED81C8A

FASTA56664,190
        10         20         30         40         50         60 
MNIFKQISSL ISSKLNELKQ RGVINTSAEN FIVEPPSNRA HGDIYTNVAM VLAKHEKKNP 

        70         80         90        100        110        120 
IEIAGILARE FKPFDEVAEV EIASPGFINM HLKIEVWHGI LKQINELKTE FGTLNIGNNQ 

       130        140        150        160        170        180 
AVNVEFVSAN PTGPLHIGHA RGAVFGDVLA NLLKKVGYNV TKEYYINDAG AQIDTLIRSV 

       190        200        210        220        230        240 
YLRYKEALGE KISIEKGLYP GEYLKPIGEG LAKKYGKELR AEEDNQIIRE YTLSSILELI 

       250        260        270        280        290        300 
KEDMSLLGVN HDVFTSEYEL RGKIEESIKI LSDKGLVYEG YLEKPKGKES ENWTSRKEML 

       310        320        330        340        350        360 
FRSTKFGDDV DRALKKEDGS WTYFASDIAY HFDKISRGFN NMIVELGSDH GGYVKRLKAV 

       370        380        390        400        410        420 
VSALSDDQAK IEVKLHNIVN FFENEKPVKM SKRSGNFLTA RDVVEEVGRD ITRFIMLTRK 

       430        440        450        460        470        480 
NDMVLDFDFA KVKEQSKDNP IFYVQYAHAR AHSLMRNAPK ELPTADPSLL KTDGELFLIK 

       490        500        510        520        530        540 
ILAKWPDVVE IAARLYEPHR ITFYLLEVAE AFHVLWGYGK SDLNMRFILE DNLNLTAARM 

       550        560 
FLVQALAHVI ASGLSIFNIE PLKEMC 

« Hide

References

[1]"Genome evolution of Wolbachia strain wPip from the Culex pipiens group."
Klasson L., Walker T., Sebaihia M., Sanders M.J., Quail M.A., Lord A., Sanders S., Earl J., O'Neill S.L., Thomson N., Sinkins S.P., Parkhill J.
Mol. Biol. Evol. 25:1877-1887(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: wPip.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM999887 Genomic DNA. Translation: CAQ55335.1.
RefSeqYP_001975962.1. NC_010981.1.

3D structure databases

ProteinModelPortalB3CNF3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING570417.WPa_1227.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAQ55335; CAQ55335; WP1227.
GeneID6385041.
KEGGwpi:WPa_1227.
PATRIC24028227. VBIWolEnd95846_1335.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
KOK01887.
OMALCNVLAK.
OrthoDBEOG6JB13C.

Enzyme and pathway databases

BioCycWEND570417:GHSW-1261-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_WOLPP
AccessionPrimary (citable) accession number: B3CNF3
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: July 22, 2008
Last modified: May 14, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries