B3AEW7 (B3AEW7_ECO57) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Toxin B EMBL EDU72892.1

Gene names

ORF Names:

ECH7EC4401_1991 EMBL EDU72892.1

Organism

Escherichia coli O157:H7 str. EC4401 EMBL EDU72892.1

Taxonomic identifier

478004 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	3169 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Ontologies

Gene Ontology (GO)
Biological process	pathogenesis Inferred from electronic annotation. Source: InterPro
Molecular function	cysteine-type endopeptidase activity Inferred from electronic annotation. Source: InterPro transferase activity, transferring glycosyl groups Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B3AEW7 [UniParc]. Last modified July 22, 2008. Version 1. Checksum: C2CDB48A72BD5FD1	FASTA	3,169	361,977
	10 20 30 40 50 60 MIHPGSSLDK AINNTRVKNV STDVKHGQIQ ERKRNFIYKK NDDISSRFKL YSSLVKQKNA 70 80 90 100 110 120 TEDVVLIGKM ILDEVRSYRT IHNDRNIVSN SGNWKTSFLC NLARLLYSIF NGSNYFCSRE 130 140 150 160 170 180 GENNSSPSST LLTIHQPEKQ ELLQQKSIKH LPTSNNIDGY IKIRKTRGAE DQTTTITQSL 190 200 210 220 230 240 IINELLNGVD RNTIPFQKIS ELNDIIHSYE NMQIKNSRKG IEILVKQGEL LSSLINDNKG 250 260 270 280 290 300 NKQLSDNASK IINLLGIEYQ SHKVDIEPFI HAVWVAGAPP DNTFSYITAF LNTYKDYTYL 310 320 330 340 350 360 LWIDPNAFGA AKFSGILKNI AMNYAIMRLR RTNPHLAEEM NEVILKIQNI QNETIEFKET 370 380 390 400 410 420 RERLKELENR YKSLTSETKE KFNVFFLESM IGMQDNYFTY CISNGISNTD DISRLDFLTN 430 440 450 460 470 480 VLKLSPEVQN DFKSTVEKNK RDIDLLKNTI SQKFGDRFQL RDINTLESFK KPQDYFFYQQ 490 500 510 520 530 540 EMLLRWNYAA ASDQVRINIL KEYGGIYTDT DILPAYSDKV SQIINEKSDD KRFFEDLKLR 550 560 570 580 590 600 RIISESILSL IKGEKYSIKH DGLDETTLNQ LNNILSEIEK LTIDDYFKPV ETKVVRDTFK 610 620 630 640 650 660 IFKRYQKWTE NTWNIRGNNN FMLTHKGSKC IDFILSGQKK QYLELQRIRD NISYNNLFYT 670 680 690 700 710 720 TEDLKSLNNV AIGGIPAKKY LEHGLFSEYR QDGTIPYVVS TLNISGPDMI MRQMKKYYKS 730 740 750 760 770 780 LGRIGEVHIK DNKLSDVNFL GVYASSNKDN KSFNWLNPVS VGINDITPDD ESSWAVRNND 790 800 810 820 830 840 INKILFEKIN CHVPEKLPTS LYYEIDSRSF FQGWDNKSIK HVTEINKDLI KDINLLLTSS 850 860 870 880 890 900 NIDVKLLIKL DRELYAISSK IDNPLALRSI RTLQLQLANY VTSNTFEPEN TINFIYDFYR 910 920 930 940 950 960 KKQDDLLSAI KLFSRNDADT KIIVWYNSVM EKNVFLREVI SCVLRSKKVD SYINENKKNL 970 980 990 1000 1010 1020 SKEDAGALRD YAKLKMKELF SMLDDDGYKK IITTNAYIKE RDKLSGIIYN IENSIISGHE 1030 1040 1050 1060 1070 1080 SFDIIRSNQH EWGDLSTVEQ FKKFEFYVKS ELSSAKSIFD DIKNKYITDP ETKRNVLYHQ 1090 1100 1110 1120 1130 1140 LDSDIKERIA FLDISHYAYP GSLLEKLQLS GYVFSDINII AEYLLASYGV SGHYSHGVVY 1150 1160 1170 1180 1190 1200 PAPSDKLLEL LRRHTKSNSE WIEKITPYVY DILSDNVSNV LRPPLSEEQK KILNDIKLEI 1210 1220 1230 1240 1250 1260 SKSVSEQYFM KLTEQKSSVI GIKYSVDFDR YNENLFLSLP INQNLTLPFM YRYFEMLYDI 1270 1280 1290 1300 1310 1320 HIGIIENKAN REFIYSKFSS LNLDFLINDE RVLNLEGLIK KYKYLSLSEI HRTLTNSTSF 1330 1340 1350 1360 1370 1380 ADISIPLLQT ICPSITTIIK KTEYYGHQLT NAMTVASVVK PYDFSNLGAI NSIDKSVSDV 1390 1400 1410 1420 1430 1440 PALHTIVEQA KYNLLSWNDF YNTHASIWDT IARQHKSTNI EFHPQSLLFD RDSKGKCLGL 1450 1460 1470 1480 1490 1500 SLLYLDTGGY GGGYQKLRHN IDTASTLYQT KYNDNLKLSN RDDFFLRKTQ RIITMSNELG 1510 1520 1530 1540 1550 1560 NNRLKNAQLE VLELKDPILT EGILYQRRIS SLLITTEYHS LALQQISSFW RVTDPNFGHC 1570 1580 1590 1600 1610 1620 DFHSLAQALT FIKNITSNRN FSSLYGSGIV KIYFSESLNN WKYIKLPLVQ TGSLLRDIYL 1630 1640 1650 1660 1670 1680 TTPEKLSTSG GSLNIMGHLV PVSFIYDIGG VINGNRISES TDVKNKIRSL KINGDILQHY 1690 1700 1710 1720 1730 1740 INTHYLSEEQ TQKIKDIVDF LGIQDNTIKV KLESDIKPIS EIQQPLHSIL SRQKEHVKNL 1750 1760 1770 1780 1790 1800 LSGLLDEFSN KLRKQGLSLK TNVLSVNNFK ESKINSDTVE VTVTDLQGRL YRVDIDTRVI 1810 1820 1830 1840 1850 1860 GLTFKEGINS LSEALEHMNI DAIMSVIGLV QYARMIKMND NISAIDHAGA VSDIKNIVDK 1870 1880 1890 1900 1910 1920 FLGGILTLTN NRVYNPGGVS GASLEGFISS GLEVCASRMG GTAGRYLSNV AKVIKLPLLD 1930 1940 1950 1960 1970 1980 IGINIWSLYD SSLNHAKATT QIEYISTAID VSFSSINTAL SIGAIAYPPL AIAIVPITIF 1990 2000 2010 2020 2030 2040 SHEVKNYAVY VNQINERHKL WLEAEKYLDN GSAKVLSINK ATGIIDLSNN QVLGNIYLDM 2050 2060 2070 2080 2090 2100 RENPPILHGE KSYNSGKNIG SHPDMTDREI MESRAYNFAC TKLSDAGEPD IFGWGDKEIC 2110 2120 2130 2140 2150 2160 NSMELSESQL ANGYSNRQWP SQIPVIPEGI YNTVYLGYGE TLRANTEVTL SSTGYFYEIA 2170 2180 2190 2200 2210 2220 RAYTDDELSE PLLTVCNQHS HVIGGKEPLT IIIPAIEHGM LGSNLHMIER FKNYNFSISG 2230 2240 2250 2260 2270 2280 GKGGIKLMVG GIGDYNIECT PGVRNIISFE QLSRDFNLDL DLSDGRKQNF NFHHPSGFYS 2290 2300 2310 2320 2330 2340 GKVMSITQKG INAVVGTKLG YDKIRGNNLD NTFSLGSGGG VIYSGGGSNT YFVPATLQDN 2350 2360 2370 2380 2390 2400 LHIYISEKSN GNHIILGDMH SRLSIECHFS NNEREFIKMG YYNGCDVILE SDTIQKIKSF 2410 2420 2430 2440 2450 2460 AKNITIQTAD GVMANWDDKL NTLSVYSIDM IAWRDKNKTA KEPLPVDVIQ LTNWRMHNTC 2470 2480 2490 2500 2510 2520 SLFYDKYQVD IEANKLTYTV LFPDTELPVQ LNYTSIIYGN HGAKYTFLNS GSKTIDIHIL 2530 2540 2550 2560 2570 2580 DKNSDYDTFD FRNIIFEHYT NEIFISFDNQ GGFVISILNN ATSEAANINV FRKNMTSLDS 2590 2600 2610 2620 2630 2640 SGSLIYLPSG DIYHISDIYK MSRGRKSFKL NVEKKPDIDD IINVAILETS YLQIKKIPNN 2650 2660 2670 2680 2690 2700 DDSDYILCLD NPNLSSYTLN FNDLSGYISS LWDNIRGSFT PFHKNTVNIA PNEKKYISLI 2710 2720 2730 2740 2750 2760 GLDKLSFNID VFRQALEVKN KNSYKISKFT WETYGDIVVS PEDRISHLEL DGFNYFSQPE 2770 2780 2790 2800 2810 2820 LDTPISDSFS YLYDNFQIVD SDVHIKLLHL NRETKQITPH RIILKRYFID SFAKTSITDR 2830 2840 2850 2860 2870 2880 EKNIYPVICD SPDHFTSDIY RHPFRIVLGN KTLYPSEELV KFISTSKEYL SNMDVINNVI 2890 2900 2910 2920 2930 2940 VPQKTTKKNK LSIVSLNSNI KNDIVLSGVM TGTSKIFHLN NSGDLLLTTS KTHGGGVVVI 2950 2960 2970 2980 2990 3000 FKDFINNWWK YNLTLITVPI DNKLSDNRIN ITPMGIKIQE TVSGNDRLFF YPTPLKNGCF 3010 3020 3030 3040 3050 3060 ILHNPLYSNS FPSLYSHELF DLIEAYRNPT YSYLQNNIIN RYIHTVSEYA GKDGIANMSL 3070 3080 3090 3100 3110 3120 SIYAYSTCRF WSKESVAVGD TIKLSNYEHI EFSFNSFSKD YFREQNSDIY KIFFKIASSS 3130 3140 3150 3160 NSVVVDKNTL TQKNFLENNT FFSITGIDES LYEKHIIFIT LKVIVPSKK

References

[1]	"Annotation of Escherichia coli O157:H7 str. EC4401." Eppinger M., Ravel J., Mammel M.K., LeClerc J.E., Cebula T.A., Sebastian Y. Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: EC4401 EMBL EDU72892.1.
[2]	Rosovitz M.J., Ravel J. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: EC4401 EMBL EDU72892.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	ABHR01000054 Genomic DNA. Translation: EDU72892.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
PATRIC	29337237. VBIEscCol43159_5319.
Phylogenomic databases
OMA	ANTEVIR.
Family and domain databases
InterPro	IPR021882. DUF3491. IPR006473. Peptidase_C58_Yopt. IPR024770. TcdA/TcdB_cat. IPR024772. TcdA/TcdB_N. [Graphical view]
Pfam	PF11996. DUF3491. 1 hit. PF12919. TcdA_TcdB. 1 hit. PF12918. TcdB_N. 1 hit. [Graphical view]
TIGRFAMs	TIGR01586. YopT_cys_prot. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B3AEW7_ECO57

Accession

Primary (citable) accession number: B3AEW7

Entry history

Integrated into UniProtKB/TrEMBL:	July 22, 2008
Last sequence update:	July 22, 2008
Last modified:	December 14, 2011
This is version 13 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)