B3A0S4 (PRP3_LOTGI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Proline-rich protein 3 Alternative name(s): Uncharacterized shell protein 25 Short name=LUSP-25
Organism	Lottia gigantea (Owl limpet)
Taxonomic identifier	225164 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Lophotrochozoa › Mollusca › Gastropoda › Patellogastropoda › Lottioidea › Lottiidae › Lottia

Protein attributes

Sequence length	195 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Subcellular location	Secreted Ref.2.
Tissue specificity	Component of the acid-insoluble organic matrix of calcified layers of the shell (at protein level). Ref.2

Ontologies

Keywords
Cellular component	Secreted
Domain	Signal
Technical term	Direct protein sequencing
Gene Ontology (GO)
Cellular_component	extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 29	29	Potential
	Chain	30 – 195	166	Proline-rich protein 3		PRO_0000415241
Regions
	Compositional bias	60 – 79	20	Pro-rich

Sequences

	Sequence		Length	Mass (Da)
	B3A0S4 [UniParc]. Last modified January 25, 2012. Version 1. Checksum: 0C7A8361364A35D0	FASTA	195	20,857
	10 20 30 40 50 60 MKMNFFNSFP QYGVYILGLN LLLCGVSEGF IGFGMDGFEE MFPLLMLGGM NGGQSNYVRP 70 80 90 100 110 120 KPIAPTLPPT PPPPMVKPPS ITWRWVPNTR YTWPLFNNMQ WPQYNPYVLP LANNAMAKTG 130 140 150 160 170 180 SAFNTNTISG TKASSGNAMP VLPAPNAQMI SSGGPVPPAA GLMNGMGMGL AGSNMAAANQ 190 MTWNTQTTSK GSTPM

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"DOE Joint Genome Institute Lottia gigantea EST project." Richardson P., Lucas S., Rokhsar D., Wang M., Lindquist E.A. Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], IDENTIFICATION. Tissue: Larva.
[2]	"The shell-forming proteome of Lottia gigantea reveals both deep conservations and lineage-specific novelties." Marie B., Jackson D.J., Ramos-Silva P., Zanella-Cleon I., Guichard N., Marin F. FEBS J. 280:214-232(2013) [PubMed] [Europe PMC] [Abstract] Cited for: PROTEIN SEQUENCE OF 119-132, SUBCELLULAR LOCATION, TISSUE SPECIFICITY. Tissue: Shell.

Cross-references

Sequence databases
EMBL GenBank DDBJ	FC756322 mRNA. No translation available.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

PRP3_LOTGI

Accession

Primary (citable) accession number: B3A0S4

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 25, 2012
Last sequence update:	January 25, 2012
Last modified:	April 3, 2013
This is version 4 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)