B3A0P1 (DGLSP_LOTGI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Aspartate, glycine, lysine and serine-rich protein
Organism	Lottia gigantea (Owl limpet)
Taxonomic identifier	225164 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Lophotrochozoa › Mollusca › Gastropoda › Patellogastropoda › Lottioidea › Lottiidae › Lottia

Protein attributes

Sequence length	977 AA.
Sequence status	Fragments.
Protein existence	Evidence at protein level

General annotation (Comments)

Subcellular location	Secreted Ref.2.
Tissue specificity	Component of the acid-insoluble and acid-soluble organic matrix of calcified layers of the shell (at protein level). Ref.2

Ontologies

Keywords
Cellular component	Secreted
PTM	Glycoprotein
Technical term	Direct protein sequencing
Gene Ontology (GO)
Cellular_component	extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 977	977	Aspartate, glycine, lysine and serine-rich protein		PRO_0000415245
Regions
	Compositional bias	141 – 649	509	Gly-rich
	Compositional bias	446 – 531	86	Lys-rich
	Compositional bias	643 – 679	37	Asp-rich
	Compositional bias	681 – 846	166	Ser-rich
Amino acid modifications
	Glycosylation	136	1	N-linked (GlcNAc...) Potential
Experimental info
	Non-adjacent residues	444 – 445	2
	Non-terminal residue	1	1

Sequences

	Sequence		Length	Mass (Da)
	B3A0P1 [UniParc]. Last modified January 25, 2012. Version 1. Checksum: 2D581F55DA06FE17	FASTA	977	96,357
	10 20 30 40 50 60 SFYDYEFEST FEYSSEINSI VDGVLPDVDS GFPTDTEETK SEPKQPDTKP EQPSVSKPDS 70 80 90 100 110 120 SVNGIVPGVS EPKPKQPSGS KPDGSAPGLK PGGGKPEGGI KPEPQVPITN LGSSTSQSSS 130 140 150 160 170 180 YISITNLYDI LSIIFNLSHI GGTGKGYTDR VSGGVGIGAS GGAGGVGGAG GVGGAGGVGG 190 200 210 220 230 240 AGGAGGADGA SVGAGGGADG GAYGGGYGAG YGGADGGADG GADGGGYGGA DGGVGAGGYG 250 260 270 280 290 300 GAGGGAGGGD YYSDSSDSSD SDSSGSDSSE SGSSESGSYY TGYNNDGSLG DNGRGSSGHR 310 320 330 340 350 360 YSDHGSPGNG SPDNGTPGSG SSRYTFSDDG SLAYKSQDNG TPGRKATNYR FSDDGSLAYG 370 380 390 400 410 420 AQDNGKPGSG SPRYRYSDDG SLGNGFPDNG ASVGISPSIE SPGGPVLGSL EDELLGSDSS 430 440 450 460 470 480 DEDDIDDGLG GLGLGAGPGG PGGFVKTPKH KPRTDKKKKP DDKPKRKPKT SRKPKTSRKP 490 500 510 520 530 540 KTSRKPKTSR KSKTSRKTKT SRKSKRKSTR KTTRKSSRKV SRKTSRKPRR KITRRPVQRK 550 560 570 580 590 600 QPREYKQESP EVEREHSAPS TTNVEIYRDI IKILITSLTS SRGDNGKSGD DGSGSGNGGG 610 620 630 640 650 660 DDGNGGGAGN GGGAGNGGGA GNGGGAGNGG GNGGGGNGGG GNDNGNDNGN DDCHYDDDDE 670 680 690 700 710 720 HRNRCEDDDD YREKCCDDDE SGGSGNFDLS SILKLMQGQS GSSSSSSATE SESSSTSTTP 730 740 750 760 770 780 STSSLDLSAI LSTLSGRSQK TRSGSALDIS SLLGVTGSRP SVATSRGSGL DLSAVLSALG 790 800 810 820 830 840 GGKPSTGTTV TSKPSTGTSS APGLDLSGLL GQLGPILSGL LGPKPDSKPS TGSPSTTSKP 850 860 870 880 890 900 STGSSSGPGL DLSGLLGNLA PVLSALTGGK KPTASSKPTA PSTPSKSTGS SPGKGLDLSG 910 920 930 940 950 960 LLGKLSPAPK PKAPKPSIGS GLLPGLDLSS ILGKLSGGKK PISGSGKGSK GSSRFCRCAL 970 SCSCKSIDYG CVNIGCK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"DOE Joint Genome Institute Lottia gigantea EST project." Richardson P., Lucas S., Rokhsar D., Wang M., Lindquist E.A. Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], IDENTIFICATION. Tissue: Foot, Gonad and Mantle.
[2]	"The shell-forming proteome of Lottia gigantea reveals both deep conservations and lineage-specific novelties." Marie B., Jackson D.J., Ramos-Silva P., Zanella-Cleon I., Guichard N., Marin F. FEBS J. 280:214-232(2013) [PubMed] [Europe PMC] [Abstract] Cited for: PROTEIN SEQUENCE OF 301-335; 351-373; 544-568; 573-582; 675-694; 743-766; 871-886; 905-947 AND 958-965, SUBCELLULAR LOCATION, TISSUE SPECIFICITY. Tissue: Shell.

Cross-references

Sequence databases
EMBL GenBank DDBJ	FC572434 mRNA. No translation available. FC572435 mRNA. No translation available. FC624061 mRNA. No translation available. FC625878 mRNA. No translation available. FC639805 mRNA. No translation available.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

DGLSP_LOTGI

Accession

Primary (citable) accession number: B3A0P1

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 25, 2012
Last sequence update:	January 25, 2012
Last modified:	April 3, 2013
This is version 4 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)