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B2ZB02 (B2ZB02_BACME) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names
OrganismBacillus megaterium EMBL ACC86108.1
Taxonomic identifier1404 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus

Protein attributes

Sequence length297 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding131Zinc; via pros nitrogen PDB 3NQ5
Metal binding421Copper 1; via tele nitrogen PDB 4J6T PDB 4J6V
Metal binding601Copper 1; via tele nitrogen PDB 4J6T PDB 4J6V
Metal binding691Copper 1; via tele nitrogen PDB 4J6T PDB 4J6V
Metal binding2041Copper 2; via tele nitrogen PDB 3NM8 PDB 3NPY PDB 3NQ5 PDB 3NQ1 PDB 3NTM PDB 4HD6 PDB 4HD7 PDB 4J6T
Metal binding2081Copper 2; via tele nitrogen PDB 3NM8 PDB 3NPY PDB 3NQ5 PDB 3NQ1 PDB 3NTM PDB 4HD6 PDB 4HD7 PDB 4J6T
Metal binding2311Copper 2; via tele nitrogen PDB 3NM8 PDB 3NPY PDB 3NQ5 PDB 3NQ1 PDB 3NTM PDB 4HD6 PDB 4HD7 PDB 4J6T
Metal binding2871Zinc PDB 3NQ5

Sequences

Sequence LengthMass (Da)Tools
B2ZB02 [UniParc].

Last modified July 1, 2008. Version 1.
Checksum: F4CBDE6501B81312

FASTA29734,410
        10         20         30         40         50         60 
MSNKYRVRKN VLHLTDTEKR DFVRTVLILK EKGIYDRYIA WHGAAGKFHT PPGSDRNAAH 

        70         80         90        100        110        120 
MSSAFLPWHR EYLLRFERDL QSINPEVTLP YWEWETDAQM QDPSQSQIWS ADFMGGNGNP 

       130        140        150        160        170        180 
IKDFIVDTGP FAAGRWTTID EQGNPSGGLK RNFGATKEAP TLPTRDDVLN ALKITQYDTP 

       190        200        210        220        230        240 
PWDMTSQNSF RNQLEGFING PQLHNRVHRW VGGQMGVVPT APNDPVFFLH HANVDRIWAV 

       250        260        270        280        290 
WQIIHRNQNY QPMKNGPFGQ NFRDPMYPWN TTPEDVMNHR KLGYVYDIEL RKSKRSS 

« Hide

References

[1]"Isolation, cloning and characterization of a tyrosinase with improved activity in organic solvents from Bacillus megaterium."
Shuster V., Fishman A.
J. Mol. Microbiol. Biotechnol. 17:188-200(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: VS1 EMBL ACC86108.1.
[2]"First structures of an active bacterial tyrosinase reveal copper plasticity."
Sendovski M., Kanteev M., Ben-Yosef V.S., Adir N., Fishman A.
J. Mol. Biol. 405:227-237(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) IN COMPLEX WITH COPPER AND ZINC.
[3]"Changes in tyrosinase specificity by ionic liquids and sodium dodecyl sulfate."
Goldfeder M., Egozy M., Shuster Ben-Yosef V., Adir N., Fishman A.
Appl. Microbiol. Biotechnol. 97:1953-1961(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (3.50 ANGSTROMS) IN COMPLEX WITH COPPER.
[4]"Influencing the monophenolase/diphenolase activity ratio in tyrosinase."
Goldfeder M., Kanteev M., Adir N., Fishman A.
Biochim. Biophys. Acta 1834:629-633(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (1.80 ANGSTROMS) IN COMPLEX WITH COPPER.
[5]"The mechanism of copper uptake by tyrosinase from Bacillus megaterium."
Kanteev M., Goldfeder M., Chojnacki M., Adir N., Fishman A.
J. Biol. Inorg. Chem. 18:895-903(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (1.90 ANGSTROMS) IN COMPLEX WITH COPPER.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
EU627691 Genomic DNA. Translation: ACC86108.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3NM8X-ray2.00A/B1-297[»]
3NPYX-ray2.19A/B1-297[»]
3NQ0X-ray2.20A/B1-297[»]
3NQ1X-ray2.30A/B1-297[»]
3NQ5X-ray2.30A/B1-297[»]
3NTMX-ray2.30A/B1-297[»]
4D87X-ray3.50A/B1-297[»]
4HD4X-ray1.80A/B1-297[»]
4HD6X-ray2.00A/B1-297[»]
4HD7X-ray2.10A/B1-297[»]
4J6TX-ray2.43A/B1-297[»]
4J6UX-ray2.50A/B1-297[»]
4J6VX-ray1.90A/B1-297[»]
ProteinModelPortalB2ZB02.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D1.10.1280.10. 1 hit.
InterProIPR002227. Tyrosinase.
IPR008922. Unchr_di-copper_centre.
[Graphical view]
PfamPF00264. Tyrosinase. 1 hit.
[Graphical view]
PRINTSPR00092. TYROSINASE.
SUPFAMSSF48056. SSF48056. 1 hit.
PROSITEPS00497. TYROSINASE_1. 1 hit.
PS00498. TYROSINASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceB2ZB02.

Entry information

Entry nameB2ZB02_BACME
AccessionPrimary (citable) accession number: B2ZB02
Entry history
Integrated into UniProtKB/TrEMBL: July 1, 2008
Last sequence update: July 1, 2008
Last modified: April 16, 2014
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)