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B2W791 (BGALB_PYRTR) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable beta-galactosidase B

EC=3.2.1.23
Alternative name(s):
Lactase B
Gene names
Name:lacB
ORF Names:PTRG_05679
OrganismPyrenophora tritici-repentis (strain Pt-1C-BFP) (Wheat tan spot fungus) (Drechslera tritici-repentis) [Complete proteome]
Taxonomic identifier426418 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaDothideomycetesPleosporomycetidaePleosporalesPleosporineaePleosporaceaePyrenophora

Protein attributes

Sequence length1009 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans By similarity.

Catalytic activity

Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.

Subcellular location

Secreted By similarity.

Sequence similarities

Belongs to the glycosyl hydrolase 35 family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Polysaccharide degradation
   Cellular componentSecreted
   DomainSignal
   Molecular functionGlycosidase
Hydrolase
   PTMDisulfide bond
Glycoprotein
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processpolysaccharide catabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionbeta-galactosidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2727 Potential
Chain28 – 1009982Probable beta-galactosidase B
PRO_0000395232

Sites

Active site2021Proton donor Potential
Active site3141Nucleophile Potential
Binding site961Substrate By similarity
Binding site1411Substrate By similarity
Binding site1421Substrate; via amide nitrogen By similarity
Binding site1431Substrate By similarity
Binding site2011Substrate By similarity
Binding site2711Substrate By similarity
Binding site3791Substrate By similarity

Amino acid modifications

Glycosylation1061N-linked (GlcNAc...) Potential
Glycosylation4671N-linked (GlcNAc...) Potential
Glycosylation4951N-linked (GlcNAc...) Potential
Glycosylation5471N-linked (GlcNAc...) Potential
Glycosylation5931N-linked (GlcNAc...) Potential
Glycosylation6321N-linked (GlcNAc...) Potential
Glycosylation6721N-linked (GlcNAc...) Potential
Glycosylation7071N-linked (GlcNAc...) Potential
Glycosylation7751N-linked (GlcNAc...) Potential
Glycosylation7821N-linked (GlcNAc...) Potential
Glycosylation7891N-linked (GlcNAc...) Potential
Glycosylation7951N-linked (GlcNAc...) Potential
Glycosylation9141N-linked (GlcNAc...) Potential
Disulfide bond277 ↔ 330 By similarity

Sequences

Sequence LengthMass (Da)Tools
B2W791 [UniParc].

Last modified July 1, 2008. Version 1.
Checksum: 572EAEC64D06F663

FASTA1,009109,564
        10         20         30         40         50         60 
MKTIAGLSWI SALSSLASLP NGLGVSAQNN TPSTWPLHDN GLSDVVQWDH YSFKVNGKRL 

        70         80         90        100        110        120 
FVFSGEIHYW RIPVYEVWED LLEKIKAAGF TAFAFYGNWA YHSANNKTLD FESGAHDFSK 

       130        140        150        160        170        180 
LFEIAHRVGL YVITRPGPYV NAEANAGGFP LWLTTGAYGK LRDDDPRYLQ ALDPYFSKFS 

       190        200        210        220        230        240 
ELTSKHLVTN GGNALVYQIE NEYGEQWKDR TKKIPNDAAG RYMQALEDSA RANGIEIPLI 

       250        260        270        280        290        300 
HNDPNMNTKS WSKDYAPGAV GNVDVAGLDS YPSCWSCNLA ECTGTNGKYV AYQVVNYYDH 

       310        320        330        340        350        360 
FKEVSPTQPS FFPEFQGGSY NPWGGPEGGC PGDIGADFAN LFYRNLISQR VTAVSLYMMF 

       370        380        390        400        410        420 
GGTNWGAIAA PVTATSYDYS SPISENREIG AKFYETKNLA MFTRVADDLT VTDRLGSSSS 

       430        440        450        460        470        480 
YTTNPAVTAS ELRNPITKAA FYVTIHSVSS SSTTESFKLH ISTSVGNLTI PQHSGSIVLN 

       490        500        510        520        530        540 
GHQSKIISTD FAMGNKTLTY STAEILTYAL IDSSPVVVLS TDVGGSVEFH VKGATKGSLA 

       550        560        570        580        590        600 
SSGFTSNATF RAEAGGVTTN IERVTGMGVY QFNNGVKVVL ADKPTAYLFW APNLSNDPFA 

       610        620        630        640        650        660 
PVDQSVLIQG PYLVRGAALD GDVVALKGDV KNSTTIEVFA HETALTLSWN GKKLETSRTP 

       670        680        690        700        710        720 
YGSLKAQISA FNGTIPLPSL NDWKVNEGLP EKMPEYDDNG AAWVVANHTT TPNPTKPDTL 

       730        740        750        760        770        780 
PVLYVDEYGF HNSFHLFRGY FEGSATGAQL SVQGGLAFGW SAWLNGDLVG SWLGNTTLGV 

       790        800        810        820        830        840 
GNMTLSFANA TVHANGTNVL LIAQDNTGHD LRGGATDPRG ILRATLDGAD FTSWKIAGEA 

       850        860        870        880        890        900 
GGENIQLDPV RGPLAEGGLT AERLGWHLSG FSDCDWASAS PSTGFSGADI KFYRTTFPLD 

       910        920        930        940        950        960 
IPEDVDASFA FILNATGPKT VRVQLFVNGY QYARFNPYVG NEVKFPIPPG ILNYAGDNVI 

       970        980        990       1000 
GLSVWAQGND GAKVDVEFVQ EYAVESSWSS RFDSEYLRPE WTEERLAYA 

« Hide

References

[1]"Comparative genomics of a plant-pathogenic fungus, Pyrenophora tritici-repentis, reveals transduplication and the impact of repeat elements on pathogenicity and population divergence."
Manning V.A., Pandelova I., Dhillon B., Wilhelm L.J., Goodwin S.B., Berlin A.M., Figueroa M., Freitag M., Hane J.K., Henrissat B., Holman W.H., Kodira C.D., Martin J., Oliver R.P., Robbertse B., Schackwitz W., Schwartz D.C., Spatafora J.W. expand/collapse author list , Turgeon B.G., Yandava C., Young S., Zhou S., Zeng Q., Grigoriev I.V., Ma L.-J., Ciuffetti L.M.
G3 (Bethesda) 3:41-63(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Pt-1C-BFP.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
DS231619 Genomic DNA. Translation: EDU48599.1.
RefSeqXP_001936012.1. XM_001935977.1.

3D structure databases

ProteinModelPortalB2W791.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiEDU48599; EDU48599; PTRG_05679.
GeneID6343933.

Phylogenomic databases

OrthoDBEOG7ZGXBD.

Family and domain databases

Gene3D2.102.20.10. 1 hit.
2.60.120.260. 2 hits.
2.60.390.10. 1 hit.
3.20.20.80. 1 hit.
InterProIPR018954. Betagal_dom2.
IPR025972. BetaGal_dom3.
IPR025300. BetaGal_jelly_roll_dom.
IPR008979. Galactose-bd-like.
IPR013781. Glyco_hydro_catalytic_dom.
IPR001944. Glycoside_Hdrlase_35.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERPTHR23421. PTHR23421. 1 hit.
PfamPF10435. BetaGal_dom2. 1 hit.
PF13363. BetaGal_dom3. 1 hit.
PF13364. BetaGal_dom4_5. 2 hits.
PF01301. Glyco_hydro_35. 1 hit.
[Graphical view]
PRINTSPR00742. GLHYDRLASE35.
SUPFAMSSF117100. SSF117100. 1 hit.
SSF49785. SSF49785. 2 hits.
SSF51445. SSF51445. 1 hit.
ProtoNetSearch...

Entry information

Entry nameBGALB_PYRTR
AccessionPrimary (citable) accession number: B2W791
Entry history
Integrated into UniProtKB/Swiss-Prot: July 13, 2010
Last sequence update: July 1, 2008
Last modified: May 14, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries