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Protein

Solute carrier family 25 member 38 homolog

Gene

PTRG_00728

Organism
Pyrenophora tritici-repentis (strain Pt-1C-BFP) (Wheat tan spot fungus) (Drechslera tritici-repentis)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Mitochondrial carrier required for the biosynthesis of heme, possibly by facilitating 5-aminolevulinate (ALA) production. May act by importing glycine into mitochondria or by exchanging glycine for ALA across the mitochondrial inner membrane.UniRule annotation

GO - Molecular functioni

Keywordsi

Biological processTransport

Names & Taxonomyi

Protein namesi
Recommended name:
Solute carrier family 25 member 38 homologUniRule annotation
Gene namesi
ORF Names:PTRG_00728
OrganismiPyrenophora tritici-repentis (strain Pt-1C-BFP) (Wheat tan spot fungus) (Drechslera tritici-repentis)
Taxonomic identifieri426418 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaDothideomycetesPleosporomycetidaePleosporalesPleosporineaePleosporaceaePyrenophora
Proteomesi
  • UP000001471 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Mitochondrion inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei14 – 39Helical; Name=1UniRule annotationAdd BLAST26
Transmembranei66 – 92Helical; Name=2UniRule annotationAdd BLAST27
Transmembranei122 – 147Helical; Name=3UniRule annotationAdd BLAST26
Transmembranei175 – 198Helical; Name=4UniRule annotationAdd BLAST24
Transmembranei226 – 252Helical; Name=5UniRule annotationAdd BLAST27
Transmembranei281 – 299Helical; Name=6UniRule annotationAdd BLAST19

GO - Cellular componenti

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003789431 – 318Solute carrier family 25 member 38 homologAdd BLAST318

Interactioni

Protein-protein interaction databases

STRINGi426418.XP_001931061.1.

Structurei

3D structure databases

ProteinModelPortaliB2VSU4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati8 – 91Solcar 1Add BLAST84
Repeati116 – 200Solcar 2Add BLAST85
Repeati222 – 306Solcar 3Add BLAST85

Sequence similaritiesi

Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily. [View classification]UniRule annotation

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0766. Eukaryota.
ENOG410XRMK. LUCA.
InParanoidiB2VSU4.
OrthoDBiEOG092C3NVU.

Family and domain databases

Gene3Di1.50.40.10. 1 hit.
HAMAPiMF_03064. SLC25A38. 1 hit.
InterProiView protein in InterPro
IPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom.
IPR030847. SLC25A38.
PfamiView protein in Pfam
PF00153. Mito_carr. 3 hits.
SUPFAMiSSF103506. SSF103506. 1 hit.
PROSITEiView protein in PROSITE
PS50920. SOLCAR. 3 hits.

Sequencei

Sequence statusi: Complete.

B2VSU4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDGGKSSSS YFHFFAGLNS GILSAVLLQP ADLLKTRVQQ SRSSTLFGTI
60 70 80 90 100
QSIASGPNPV RQFWRGTLPS TLRTGFGSAI YFSSLNALRH RASLGAAGRA
110 120 130 140 150
DAAAKGAEHS SSLPKLSNTA NLATGAFART WAGFIMMPIT VLKVRYESNL
160 170 180 190 200
YAYNSLFTAS RDIFRTEGLK GFFAGFGATA VRDAPYAGLY VLFYEQSKRK
210 220 230 240 250
LSSLATKIEQ TSGASTKLST STSAGINFVS GVAAAGLGTT ITNPFDAIKT
260 270 280 290 300
RIQLMPERYG NMVQATKKMY MEEGLRCFFD GLGIRIARKA VSSALAWTLY
310
EELIRRAETL KEVVEDKI
Length:318
Mass (Da):34,364
Last modified:July 1, 2008 - v1
Checksum:iBFF739B77B742211
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS231615 Genomic DNA. Translation: EDU40166.1.
RefSeqiXP_001931061.1. XM_001931026.1.

Genome annotation databases

EnsemblFungiiEDU40166; EDU40166; PTRG_00728.
GeneIDi6340039.

Similar proteinsi

Entry informationi

Entry nameiS2538_PYRTR
AccessioniPrimary (citable) accession number: B2VSU4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 7, 2009
Last sequence update: July 1, 2008
Last modified: May 10, 2017
This is version 45 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families